SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eq5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 3eq5 SKI-LIKE PROTEIN
(Homo
sapiens) 		4 / 7 LEU A 202
SER A 199
ASP A 200
PHE A 213
 None
 1.15A 1ismB-3eq5A:
undetectable		 1ismB-3eq5A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_E_THAE5_1
(LIVER
CARBOXYLESTERASE I)		 3eq5 SKI-LIKE PROTEIN
(Homo
sapiens) 		5 / 12 VAL A 186
VAL A 170
LEU A 233
LEU A 175
LEU A 149
 None
 1.21A 1mx1E-3eq5A:
undetectable		 1mx1E-3eq5A:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3eq5 SKI-LIKE PROTEIN
(Homo
sapiens) 		3 / 3 VAL A 170
GLN A 227
CYH A 230
 None
 0.78A 5icxC-3eq5A:
undetectable
5icxF-3eq5A:
undetectable		 5icxC-3eq5A:
21.23
5icxF-3eq5A:
16.00