SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eqa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AGM_A_ACRA495_1
(GLUCOAMYLASE-471)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		12 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
TRP A 144
GLY A 145
GLU A 204
ARG A 329
TYR A 335
TRP A 341
GLU A 424
 TRS  A 701 ( 3.8A)
TRS  A 701 (-4.5A)
TRS  A 701 (-3.8A)
TRS  A 701 (-3.8A)
TRS  A 701 (-2.8A)
None
None
GOL  A 801 (-3.6A)
GOL  A 801 (-3.3A)
GOL  A 801 ( 4.1A)
None
None
 0.19A 1agmA-3eqaA:
70.0		 1agmA-3eqaA:
95.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AGM_A_ACRA495_2
(GLUCOAMYLASE-471)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 TRP A 202
GLU A 203
LEU A 439
TRP A 441
 None
TRS  A 701 ( 3.8A)
None
None
 0.18A 1agmA-3eqaA:
70.0		 1agmA-3eqaA:
95.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AGM_A_ACRA496_1
(GLUCOAMYLASE-471)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		12 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
TRP A 144
GLY A 145
GLU A 204
ARG A 329
TYR A 335
TRP A 341
GLU A 424
 TRS  A 701 ( 3.8A)
TRS  A 701 (-4.5A)
TRS  A 701 (-3.8A)
TRS  A 701 (-3.8A)
TRS  A 701 (-2.8A)
None
None
GOL  A 801 (-3.6A)
GOL  A 801 (-3.3A)
GOL  A 801 ( 4.1A)
None
None
 0.19A 1agmA-3eqaA:
70.0		 1agmA-3eqaA:
95.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AGM_A_ACRA496_2
(GLUCOAMYLASE-471)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 5 SER A 143
TRP A 202
GLU A 203
LEU A 439
TRP A 441
 None
None
TRS  A 701 ( 3.8A)
None
None
 0.57A 1agmA-3eqaA:
70.0		 1agmA-3eqaA:
95.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GAH_A_ACRA497_1
(GLUCOAMYLASE-471)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		12 / 12 TYR A  72
TRP A  76
ARG A  78
ASP A  79
TRP A 144
GLY A 145
TYR A 199
GLU A 203
GLU A 204
TYR A 335
TRP A 341
GLU A 424
 TRS  A 701 (-4.5A)
TRS  A 701 (-3.8A)
TRS  A 701 (-3.8A)
TRS  A 701 (-2.8A)
None
None
None
TRS  A 701 ( 3.8A)
GOL  A 801 (-3.6A)
GOL  A 801 ( 4.1A)
None
None
 0.24A 1gahA-3eqaA:
69.8		 1gahA-3eqaA:
95.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		6 / 6 ALA A  63
SER A 143
TRP A 202
ARG A 329
LEU A 439
TRP A 441
 TRS  A 701 ( 3.8A)
None
None
GOL  A 801 (-3.3A)
None
None
 0.22A 1gahA-3eqaA:
69.8		 1gahA-3eqaA:
95.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_N_ACTN803_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 ARG A 329
GLY A 338
ASP A 333
TYR A 313
 GOL  A 801 (-3.3A)
None
None
None
 1.28A 1kf6M-3eqaA:
undetectable
1kf6N-3eqaA:
1.5		 1kf6M-3eqaA:
21.98
1kf6N-3eqaA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		9 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
GLU A 204
ARG A 329
TYR A 335
TRP A 441
 TRS  A 701 ( 3.8A)
TRS  A 701 (-4.5A)
TRS  A 701 (-3.8A)
TRS  A 701 (-3.8A)
TRS  A 701 (-2.8A)
GOL  A 801 (-3.6A)
GOL  A 801 (-3.3A)
GOL  A 801 ( 4.1A)
None
 0.37A 1lf9A-3eqaA:
30.0		 1lf9A-3eqaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_1
(GLUCOAMYLASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  63
TYR A  72
TRP A 144
GLU A 204
TYR A 335
 TRS  A 701 ( 3.8A)
TRS  A 701 (-4.5A)
None
GOL  A 801 (-3.6A)
GOL  A 801 ( 4.1A)
 0.98A 1lf9A-3eqaA:
30.0		 1lf9A-3eqaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_A_ACRA700_2
(GLUCOAMYLASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 TRP A 202
GLU A 203
TRP A 341
LEU A 439
 None
TRS  A 701 ( 3.8A)
None
None
 0.31A 1lf9A-3eqaA:
30.1		 1lf9A-3eqaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		9 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
GLU A 204
ARG A 329
TYR A 335
TRP A 341
 TRS  A 701 ( 3.8A)
TRS  A 701 (-4.5A)
TRS  A 701 (-3.8A)
TRS  A 701 (-3.8A)
TRS  A 701 (-2.8A)
GOL  A 801 (-3.6A)
GOL  A 801 (-3.3A)
GOL  A 801 ( 4.1A)
None
 0.46A 1lf9B-3eqaA:
30.0		 1lf9B-3eqaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		6 / 12 ALA A  63
TYR A  72
TRP A 144
GLU A 204
TYR A 335
TRP A 341
 TRS  A 701 ( 3.8A)
TRS  A 701 (-4.5A)
None
GOL  A 801 (-3.6A)
GOL  A 801 ( 4.1A)
None
 1.03A 1lf9B-3eqaA:
30.0		 1lf9B-3eqaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 GLN A 148
TRP A 144
GLU A 204
TYR A 335
TRP A 341
 None
None
GOL  A 801 (-3.6A)
GOL  A 801 ( 4.1A)
None
 1.35A 1lf9B-3eqaA:
30.0		 1lf9B-3eqaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_1
(GLUCOAMYLASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		6 / 12 TRP A  76
GLN A 148
GLU A 204
ARG A 329
TYR A 335
TRP A 341
 TRS  A 701 (-3.8A)
None
GOL  A 801 (-3.6A)
GOL  A 801 (-3.3A)
GOL  A 801 ( 4.1A)
None
 1.46A 1lf9B-3eqaA:
30.0		 1lf9B-3eqaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LF9_B_ACRB701_2
(GLUCOAMYLASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 TRP A 202
GLU A 203
LEU A 439
TRP A 441
 None
TRS  A 701 ( 3.8A)
None
None
 0.44A 1lf9B-3eqaA:
30.0		 1lf9B-3eqaA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 GLY A 129
GLU A 130
GLY A 127
GLY A 120
GLY A 198
 None
 0.90A 1n2xB-3eqaA:
undetectable		 1n2xB-3eqaA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  56
THR A 440
ILE A  42
ARG A  39
LEU A  87
 None
 0.97A 1ra8A-3eqaA:
undetectable		 1ra8A-3eqaA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 PHE A 211
ASN A 271
TRP A 202
ALA A 259
 None
 1.17A 1rqpC-3eqaA:
undetectable		 1rqpC-3eqaA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 PHE A 211
ASN A 271
TRP A 202
ALA A 259
 None
 1.16A 1rqpA-3eqaA:
undetectable		 1rqpA-3eqaA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 GLY A 163
ILE A 160
GLN A 164
VAL A  88
 None
 0.85A 1rs7B-3eqaA:
undetectable		 1rs7B-3eqaA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_1
(GLUCODEXTRANASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		9 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
GLU A 204
ARG A 329
TYR A 335
TRP A 341
 TRS  A 701 ( 3.8A)
TRS  A 701 (-4.5A)
TRS  A 701 (-3.8A)
TRS  A 701 (-3.8A)
TRS  A 701 (-2.8A)
GOL  A 801 (-3.6A)
GOL  A 801 (-3.3A)
GOL  A 801 ( 4.1A)
None
 0.54A 1ulvA-3eqaA:
9.4		 1ulvA-3eqaA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 5 GLN A 148
GLU A 203
LEU A 343
TRP A 341
 None
TRS  A 701 ( 3.8A)
None
None
 1.47A 1ulvA-3eqaA:
9.4		 1ulvA-3eqaA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ULV_A_ACRA3000_2
(GLUCODEXTRANASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 5 TRP A 202
GLU A 203
LEU A 439
TRP A 441
 None
TRS  A 701 ( 3.8A)
None
None
 0.35A 1ulvA-3eqaA:
9.4		 1ulvA-3eqaA:
19.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F6D_A_ACRA995_1
(GLUCOAMYLASE GLU1)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		12 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
TRP A 144
GLY A 145
GLU A 204
ARG A 329
TYR A 335
TRP A 341
GLU A 424
 TRS  A 701 ( 3.8A)
TRS  A 701 (-4.5A)
TRS  A 701 (-3.8A)
TRS  A 701 (-3.8A)
TRS  A 701 (-2.8A)
None
None
GOL  A 801 (-3.6A)
GOL  A 801 (-3.3A)
GOL  A 801 ( 4.1A)
None
None
 0.24A 2f6dA-3eqaA:
46.5		 2f6dA-3eqaA:
37.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F6D_A_ACRA995_2
(GLUCOAMYLASE GLU1)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 TRP A 202
GLU A 203
LEU A 439
TRP A 441
 None
TRS  A 701 ( 3.8A)
None
None
 0.15A 2f6dA-3eqaA:
46.5		 2f6dA-3eqaA:
37.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_0
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ILE A 244
ALA A 214
THR A 157
VAL A 183
GLN A 164
 None
 1.32A 2rctA-3eqaA:
undetectable		 2rctA-3eqaA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 PHE A 211
ASN A 271
TRP A 202
ALA A 259
 None
 1.16A 2v7uA-3eqaA:
undetectable		 2v7uA-3eqaA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSC_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 9 PHE A 211
SER A 209
ALA A 270
LEU A 274
GLY A 275
 None
 1.33A 2wscA-3eqaA:
0.0		 2wscA-3eqaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSE_A_PQNA1801_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 9 PHE A 211
SER A 209
ALA A 270
LEU A 274
GLY A 275
 None
 1.34A 2wseA-3eqaA:
0.1		 2wseA-3eqaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WSF_A_PQNA1802_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 9 PHE A 211
SER A 209
ALA A 270
LEU A 274
GLY A 275
 None
 1.33A 2wsfA-3eqaA:
0.0		 2wsfA-3eqaA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 ARG A 146
GLY A 129
GLU A 130
SER A 209
 None
 1.25A 2xctS-3eqaA:
undetectable
2xctU-3eqaA:
undetectable		 2xctS-3eqaA:
20.23
2xctU-3eqaA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 7 LYS A 402
LEU A 356
ALA A 405
VAL A 409
 None
 0.96A 3d2tA-3eqaA:
undetectable		 3d2tA-3eqaA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 11 THR A 176
GLN A 164
GLY A 231
THR A 228
ALA A 227
 None
 1.31A 3mg0H-3eqaA:
undetectable
3mg0I-3eqaA:
undetectable		 3mg0H-3eqaA:
20.00
3mg0I-3eqaA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 GLY A 163
ILE A 160
GLN A 164
VAL A  88
 None
 0.80A 4d39B-3eqaA:
undetectable		 4d39B-3eqaA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DFR_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  56
THR A 440
ILE A  42
ARG A  39
LEU A  87
 None
 0.94A 4dfrA-3eqaA:
undetectable		 4dfrA-3eqaA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 ASP A 333
ASP A 200
GLU A 424
ASP A 269
 None
 0.93A 4feuD-3eqaA:
undetectable		 4feuD-3eqaA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 7 ASP A 333
ASP A 200
GLU A 424
ASP A 269
 None
 0.97A 4fevB-3eqaA:
undetectable		 4fevB-3eqaA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 7 ASP A 333
ASP A 200
GLU A 424
ASP A 269
 None
 0.99A 4fewB-3eqaA:
undetectable		 4fewB-3eqaA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 ASP A 333
ASP A 200
GLU A 424
ASP A 269
 None
 0.98A 4gkhD-3eqaA:
undetectable		 4gkhD-3eqaA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 LYS A 402
LEU A 356
ALA A 405
VAL A 409
 None
 0.96A 4iizB-3eqaA:
undetectable		 4iizB-3eqaA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_A_LURA201_1
(TRANSTHYRETIN)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 LYS A 402
LEU A 356
ALA A 405
VAL A 409
 None
 0.87A 4ik6A-3eqaA:
undetectable		 4ik6A-3eqaA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_ACTA803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 GLY A 163
ILE A 160
GLN A 164
VAL A  88
 None
 0.89A 4kcnA-3eqaA:
undetectable		 4kcnA-3eqaA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 8 VAL A 306
ASP A 307
SER A 322
ALA A 348
 None
 0.92A 4m48A-3eqaA:
2.1		 4m48A-3eqaA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 GLY A  50
VAL A 135
THR A 440
ILE A  42
VAL A  83
 None
 1.19A 4okwA-3eqaA:
undetectable		 4okwA-3eqaA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		3 / 3 SER A  64
ASP A 438
GLN A 433
 None
NAG  A 551 (-3.8A)
None
 0.91A 4oltA-3eqaA:
undetectable
4oltB-3eqaA:
undetectable		 4oltA-3eqaA:
22.46
4oltB-3eqaA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB304_1
(CHITOSANASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		3 / 3 GLN A 433
SER A  64
ASP A 438
 None
None
NAG  A 551 (-3.8A)
 0.93A 4qwpA-3eqaA:
undetectable
4qwpB-3eqaA:
undetectable		 4qwpA-3eqaA:
22.46
4qwpB-3eqaA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A 466
SER A 465
GLY A 462
ALA A 227
GLY A 223
 MAN  A 600 (-4.9A)
None
None
None
None
 1.18A 4r29A-3eqaA:
undetectable		 4r29A-3eqaA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_C_SAMC301_0
(UNCHARACTERIZED
PROTEIN)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A 466
SER A 465
GLY A 462
ALA A 227
GLY A 223
 MAN  A 600 (-4.9A)
None
None
None
None
 1.21A 4r29C-3eqaA:
undetectable		 4r29C-3eqaA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ASP A 307
HIS A 302
VAL A 306
VAL A 327
ALA A 405
 None
 0.94A 4yhaA-3eqaA:
undetectable		 4yhaA-3eqaA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 10 ASP A 307
HIS A 302
VAL A 306
VAL A 327
ALA A 405
 None
 0.95A 4yhaB-3eqaA:
undetectable		 4yhaB-3eqaA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 LYS A 402
LEU A 356
ALA A 405
VAL A 409
 None
 1.06A 5a6iA-3eqaA:
undetectable		 5a6iA-3eqaA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 11 THR A 176
GLN A 164
GLY A 231
THR A 228
ALA A 227
 None
 1.17A 5bxnH-3eqaA:
undetectable
5bxnI-3eqaA:
undetectable		 5bxnH-3eqaA:
19.57
5bxnI-3eqaA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 9 LEU A 201
LEU A 273
LEU A 274
LEU A 343
ALA A 347
 None
 1.00A 5dqfA-3eqaA:
undetectable		 5dqfA-3eqaA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  56
THR A 440
ILE A  42
ARG A  39
LEU A  87
 None
 0.96A 5eajA-3eqaA:
undetectable		 5eajA-3eqaA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 SER A 266
VAL A 306
VAL A 327
LEU A 273
THR A 272
 None
 1.26A 5jnaB-3eqaA:
undetectable		 5jnaB-3eqaA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 11 SER A 266
VAL A 306
VAL A 327
LEU A 273
THR A 272
 None
 1.25A 5jnaC-3eqaA:
undetectable		 5jnaC-3eqaA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 SER A 266
VAL A 306
VAL A 327
LEU A 273
THR A 272
 None
 1.23A 5jnaD-3eqaA:
undetectable		 5jnaD-3eqaA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M50_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 VAL A 183
ASP A 186
THR A 101
GLY A  81
LEU A  84
 None
 1.07A 5m50E-3eqaA:
undetectable		 5m50E-3eqaA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		6 / 10 PHE A 211
SER A 209
ALA A 270
LEU A 274
GLY A 275
ILE A  42
 None
 1.50A 5oy01-3eqaA:
undetectable
5oy07-3eqaA:
undetectable		 5oy01-3eqaA:
11.85
5oy07-3eqaA:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		5 / 12 ALA A  56
THR A 440
ILE A  42
ARG A  39
LEU A  87
 None
 0.97A 5ujxA-3eqaA:
undetectable		 5ujxA-3eqaA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 7 GLY A  81
TRP A 441
ASP A 150
ASP A 186
 None
 1.09A 5vlmE-3eqaA:
1.4		 5vlmE-3eqaA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_H_BEZH201_0
(NS3 PROTEASE)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 5 SER A 124
TYR A 482
GLY A 125
TYR A 193
 None
 1.15A 5yodH-3eqaA:
undetectable		 5yodH-3eqaA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 6 LEU A 446
ASP A 354
GLN A 292
GLU A 350
 None
 1.47A 6djzC-3eqaA:
undetectable		 6djzC-3eqaA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		3 / 3 GLN A 425
TYR A 336
ASN A 339
 None
 1.07A 6dwdC-3eqaA:
undetectable		 6dwdC-3eqaA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_1
(GLUCOAMYLASE P)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		12 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
TRP A 144
GLY A 145
GLU A 204
ARG A 329
TYR A 335
TRP A 341
TRP A 441
 TRS  A 701 ( 3.8A)
TRS  A 701 (-4.5A)
TRS  A 701 (-3.8A)
TRS  A 701 (-3.8A)
TRS  A 701 (-2.8A)
None
None
GOL  A 801 (-3.6A)
GOL  A 801 (-3.3A)
GOL  A 801 ( 4.1A)
None
None
 0.42A 6fhwA-3eqaA:
61.7		 6fhwA-3eqaA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		3 / 3 TRP A 202
GLU A 203
GLU A 424
 None
TRS  A 701 ( 3.8A)
None
 0.19A 6fhwA-3eqaA:
61.7		 6fhwA-3eqaA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_A_ACRA801_2
(GLUCOAMYLASE P)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		3 / 3 TRP A 441
GLU A 424
GLU A 203
 None
None
TRS  A 701 ( 3.8A)
 0.87A 6fhwA-3eqaA:
61.7		 6fhwA-3eqaA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_1
(GLUCOAMYLASE P)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		12 / 12 ALA A  63
TYR A  72
TRP A  76
ARG A  78
ASP A  79
TRP A 144
GLY A 145
GLU A 204
ARG A 329
TYR A 335
TRP A 341
TRP A 441
 TRS  A 701 ( 3.8A)
TRS  A 701 (-4.5A)
TRS  A 701 (-3.8A)
TRS  A 701 (-3.8A)
TRS  A 701 (-2.8A)
None
None
GOL  A 801 (-3.6A)
GOL  A 801 (-3.3A)
GOL  A 801 ( 4.1A)
None
None
 0.42A 6fhwB-3eqaA:
62.0		 6fhwB-3eqaA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FHW_B_ACRB801_2
(GLUCOAMYLASE P)		 3eqa GLUCOAMYLASE
(Aspergillus
niger) 		4 / 4 TRP A 202
GLU A 203
GLU A 424
LEU A 439
 None
TRS  A 701 ( 3.8A)
None
None
 0.22A 6fhwB-3eqaA:
62.0		 6fhwB-3eqaA:
11.99