SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eqn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_C_DVAC6_0
(GRAMICIDIN A)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		3 / 3 ALA A 444
VAL A 475
TRP A 505
 None
 0.87A 1av2C-3eqnA:
undetectable
1av2D-3eqnA:
undetectable		 1av2C-3eqnA:
2.74
1av2D-3eqnA:
2.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E3V_A_DXCA801_0
(STEROID
DELTA-ISOMERASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 476
PHE A 491
VAL A 503
LEU A 556
ALA A 519
 None
 1.27A 1e3vA-3eqnA:
undetectable		 1e3vA-3eqnA:
9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 4 GLY A 518
ASP A 509
GLY A 600
THR A 559
 None
None
ZN  A 756 (-4.5A)
None
 0.89A 1hxbB-3eqnA:
undetectable		 1hxbB-3eqnA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JR1_A_MOAA1332_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE 2)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 11 SER A 204
ASN A 224
GLY A 206
GLY A 680
GLN A 631
 GOL  A 764 (-3.5A)
None
None
None
GOL  A 764 ( 4.1A)
 1.41A 1jr1A-3eqnA:
undetectable		 1jr1A-3eqnA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 10 GLY A 432
PHE A  33
VAL A 455
MET A 457
HIS A 407
 None
 1.27A 1pwyE-3eqnA:
undetectable		 1pwyE-3eqnA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 ALA A 413
TYR A 434
ILE A 414
ASP A 430
 None
 1.11A 1upfC-3eqnA:
undetectable		 1upfC-3eqnA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 ILE A 170
GLY A 169
SER A 166
ILE A 127
ALA A 120
 None
 1.00A 1vq1B-3eqnA:
undetectable		 1vq1B-3eqnA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_C_DVAC6_0
(GRAMICIDIN D)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		3 / 3 ALA A 444
VAL A 475
TRP A 505
 None
 0.80A 1w5uC-3eqnA:
undetectable
1w5uD-3eqnA:
undetectable		 1w5uC-3eqnA:
2.74
1w5uD-3eqnA:
2.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_A_SAMA1300_0
(UPF0088 PROTEIN
AQ_165)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 VAL A 310
LEU A 629
THR A 717
LEU A 716
THR A 747
 None
 0.74A 2egvA-3eqnA:
undetectable		 2egvA-3eqnA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EGV_B_SAMB1400_0
(UPF0088 PROTEIN
AQ_165)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 VAL A 310
LEU A 629
THR A 717
LEU A 716
THR A 747
 None
 0.68A 2egvB-3eqnA:
undetectable		 2egvB-3eqnA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_B_DVAB6_0
(GRAMICIDIN D)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		3 / 3 TRP A 505
ALA A 444
VAL A 475
 None
 0.85A 2izqA-3eqnA:
undetectable
2izqB-3eqnA:
undetectable		 2izqA-3eqnA:
2.74
2izqB-3eqnA:
2.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 PHE A 149
PHE A 150
TRP A 570
GLY A 527
 None
 1.33A 2qmzA-3eqnA:
undetectable
2qmzB-3eqnA:
undetectable		 2qmzA-3eqnA:
16.69
2qmzB-3eqnA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 PHE A 149
PHE A 150
TRP A 570
GLY A 528
 None
 1.15A 2qmzA-3eqnA:
undetectable
2qmzB-3eqnA:
undetectable		 2qmzA-3eqnA:
16.69
2qmzB-3eqnA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		3 / 3 GLN A 535
THR A 492
TRP A 453
 None
 1.16A 2rctA-3eqnA:
undetectable		 2rctA-3eqnA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 7 VAL A 484
ILE A 442
VAL A 507
GLY A 445
THR A 446
 None
 0.94A 2xrzB-3eqnA:
undetectable		 2xrzB-3eqnA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 7 GLY A 680
ASP A 744
TYR A 682
ARG A 735
 None
 1.33A 3arrA-3eqnA:
undetectable		 3arrA-3eqnA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 8 VAL A 295
PHE A 213
GLY A 219
ALA A 240
GLU A 281
 None
 1.21A 3aruA-3eqnA:
undetectable		 3aruA-3eqnA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		3 / 3 SER A 301
GLY A 307
GLY A 345
 None
 0.56A 3bogA-3eqnA:
undetectable
3bogC-3eqnA:
undetectable		 3bogA-3eqnA:
undetectable
3bogC-3eqnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_1
(CYTOCHROME P450 2R1)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 LEU A 558
ALA A 519
GLY A 600
MET A 569
THR A 607
 None
None
ZN  A 756 (-4.5A)
None
None
 1.05A 3c6gA-3eqnA:
undetectable		 3c6gA-3eqnA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 ASN A 624
ILE A 605
GLY A 606
LEU A 371
PRO A 368
 None
 1.13A 3eeyD-3eqnA:
undetectable		 3eeyD-3eqnA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 4 GLY A 518
ASP A 509
GLY A 600
THR A 559
 None
None
ZN  A 756 (-4.5A)
None
 0.93A 3k4vC-3eqnA:
undetectable		 3k4vC-3eqnA:
8.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_A_DVAA6_0
(GRAMICIDIN D)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		3 / 3 ALA A 444
VAL A 475
TRP A 505
 None
 0.81A 3l8lA-3eqnA:
undetectable
3l8lB-3eqnA:
undetectable		 3l8lA-3eqnA:
2.74
3l8lB-3eqnA:
2.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_C_DVAC6_0
(GRAMICIDIN D)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		3 / 3 ALA A 444
VAL A 475
TRP A 505
 None
 0.73A 3l8lC-3eqnA:
undetectable
3l8lD-3eqnA:
undetectable		 3l8lC-3eqnA:
2.74
3l8lD-3eqnA:
2.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 9 LEU A 619
VAL A 676
ALA A 630
THR A 632
ALA A 665
 None
 1.24A 3mdtA-3eqnA:
undetectable		 3mdtA-3eqnA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 11 TYR A 626
GLY A 673
ALA A 623
ILE A 711
ALA A 712
 None
 0.87A 3nmuB-3eqnA:
undetectable
3nmuJ-3eqnA:
undetectable		 3nmuB-3eqnA:
17.10
3nmuJ-3eqnA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 169
ILE A 183
ASP A 159
LEU A 160
ARG A 161
 None
 1.11A 3o7wA-3eqnA:
undetectable		 3o7wA-3eqnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 197
ILE A 183
ASP A 159
LEU A 160
ARG A 161
 None
 1.11A 3o7wA-3eqnA:
undetectable		 3o7wA-3eqnA:
15.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 PHE A 653
ILE A 613
ASN A 621
PHE A 647
 None
 1.37A 3octA-3eqnA:
undetectable		 3octA-3eqnA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 10 ASP A 552
ALA A 551
ILE A 613
SER A 609
VAL A 571
 None
 0.93A 3ogpA-3eqnA:
undetectable		 3ogpA-3eqnA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 ALA A 551
GLY A 495
GLY A 527
LEU A 573
ALA A 498
 None
 0.91A 3ou6B-3eqnA:
undetectable		 3ou6B-3eqnA:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 LEU A 566
VAL A 507
GLY A 561
SER A 598
LEU A 558
 None
 0.97A 3pghC-3eqnA:
undetectable		 3pghC-3eqnA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_D_FLPD701_1
(CYCLOOXYGENASE-2)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 LEU A 566
VAL A 507
GLY A 561
SER A 598
LEU A 558
 None
 0.97A 3pghD-3eqnA:
undetectable		 3pghD-3eqnA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PS9_A_SAMA670_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 GLY A 169
ASP A 159
GLY A 197
PHE A 213
MET A 187
 None
 1.12A 3ps9A-3eqnA:
undetectable		 3ps9A-3eqnA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T01_A_PPFA503_1
(PHOSPHONOACETATE
HYDROLASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 7 ASN A 155
ASP A 488
ILE A 181
HIS A 383
 None
ZN  A 757 (-4.6A)
None
ZN  A 757 ( 3.4A)
 0.98A 3t01A-3eqnA:
undetectable		 3t01A-3eqnA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		3 / 3 ASN A 148
ALA A 132
ARG A 151
 None
 0.88A 3tj7C-3eqnA:
undetectable
3tj7D-3eqnA:
undetectable		 3tj7C-3eqnA:
12.15
3tj7D-3eqnA:
12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TVX_B_PNXB902_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4A)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 7 ASN A  24
ILE A  25
PHE A 428
PHE A  43
 None
 1.21A 3tvxB-3eqnA:
undetectable		 3tvxB-3eqnA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 6 MET A 595
LEU A 554
GLN A 470
PRO A 469
 None
 1.38A 3vkxA-3eqnA:
undetectable		 3vkxA-3eqnA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 6 MET A 595
LEU A 554
PRO A 471
GLN A 470
 None
 1.41A 3vkxA-3eqnA:
undetectable		 3vkxA-3eqnA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 9 ALA A 343
GLY A 345
LEU A 305
ASN A 738
ILE A 746
 None
 1.46A 3wdmA-3eqnA:
undetectable		 3wdmA-3eqnA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 11 TYR A 714
LEU A 316
ILE A 283
ILE A 339
TYR A 626
 None
 1.28A 4a7aA-3eqnA:
undetectable		 4a7aA-3eqnA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 8 TYR A 386
VAL A 484
VAL A 475
ILE A 448
 None
 1.08A 4aftD-3eqnA:
undetectable
4aftE-3eqnA:
undetectable		 4aftD-3eqnA:
13.72
4aftE-3eqnA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 VAL A 503
PHE A 491
GLY A 555
VAL A 571
HIS A 523
 None
 1.37A 4bvaA-3eqnA:
undetectable		 4bvaA-3eqnA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_B_T3B1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 VAL A 503
PHE A 491
GLY A 555
VAL A 571
HIS A 523
 None
 1.39A 4bvaB-3eqnA:
undetectable		 4bvaB-3eqnA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 SER A 152
VAL A 153
GLN A 196
THR A 168
HIS A 171
 None
 1.44A 4c49C-3eqnA:
undetectable		 4c49C-3eqnA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FAK_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 10 LEU A 556
ILE A 501
ILE A 594
GLY A 593
GLY A 592
 None
 1.02A 4fakA-3eqnA:
undetectable		 4fakA-3eqnA:
11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 7 ASN A 246
GLY A 279
VAL A 278
PHE A 357
 None
 0.88A 4fglC-3eqnA:
undetectable		 4fglC-3eqnA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_1
(MEMBRANE LIPOPROTEIN
TPN38(B))		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 SER A  79
TYR A 104
GLN A 176
ASP A 133
GLN A 141
 None
None
GOL  A 764 (-3.1A)
None
None
 1.33A 4iilA-3eqnA:
undetectable		 4iilA-3eqnA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 8 HIS A 576
ASN A 147
ASP A 579
LEU A 578
ILE A 525
 ZN  A 758 (-3.2A)
GOL  A 766 ( 3.7A)
None
None
None
 1.37A 4k0bA-3eqnA:
undetectable		 4k0bA-3eqnA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 TYR A  94
PHE A 156
GLN A  23
VAL A  46
LEU A 108
 None
 1.39A 4k39A-3eqnA:
undetectable		 4k39A-3eqnA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 11 PHE A 463
GLY A 495
ARG A 494
GLY A 460
ALA A 419
 None
 0.98A 4l6v1-3eqnA:
undetectable
4l6v6-3eqnA:
undetectable		 4l6v1-3eqnA:
21.65
4l6v6-3eqnA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 8 HIS A 576
ASN A 147
ASP A 579
LEU A 578
ILE A 525
 ZN  A 758 (-3.2A)
GOL  A 766 ( 3.7A)
None
None
None
 1.44A 4l7iA-3eqnA:
undetectable		 4l7iA-3eqnA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 10 THR A 408
ILE A 440
ALA A 402
ALA A 413
ILE A 414
 None
 1.07A 4lbgA-3eqnA:
undetectable		 4lbgA-3eqnA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_A_ADNA501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 GLN A 292
THR A 291
THR A 337
LEU A 332
 None
 0.86A 4lvcA-3eqnA:
undetectable		 4lvcA-3eqnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 GLN A 292
THR A 291
THR A 337
LEU A 332
 None
 0.85A 4lvcB-3eqnA:
undetectable		 4lvcB-3eqnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_C_ADNC501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 GLN A 292
THR A 291
THR A 337
LEU A 332
 None
 0.85A 4lvcC-3eqnA:
undetectable		 4lvcC-3eqnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_1
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 VAL A 449
GLN A 107
ILE A 181
ASN A 155
HIS A 383
 None
None
None
None
ZN  A 757 ( 3.4A)
 1.42A 4s0vA-3eqnA:
undetectable		 4s0vA-3eqnA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_2
(MINERALOCORTICOID
RECEPTOR)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 6 LEU A 554
LEU A 573
THR A 493
VAL A 472
 None
 1.04A 4udaA-3eqnA:
undetectable		 4udaA-3eqnA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 LEU A 118
VAL A  96
THR A  60
VAL A  87
PHE A  89
 None
 1.22A 4wnwA-3eqnA:
undetectable		 4wnwA-3eqnA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 VAL A 475
GLY A 518
ALA A 519
ILE A 473
THR A 522
 None
 0.84A 4xdrA-3eqnA:
undetectable		 4xdrA-3eqnA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 6 LEU A 554
ASP A 654
ILE A 526
PRO A 643
 None
 1.01A 4xi3C-3eqnA:
undetectable		 4xi3C-3eqnA:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 10 PHE A 207
TYR A 565
GLY A 209
GLY A 568
MET A 569
 None
 1.31A 4xpbA-3eqnA:
undetectable		 4xpbA-3eqnA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 LEU A 232
PHE A 213
GLY A 197
LEU A 180
PHE A 207
 None
 1.18A 4ze1A-3eqnA:
undetectable		 4ze1A-3eqnA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 8 ALA A 444
GLY A 476
ALA A 477
GLY A 479
 None
 0.64A 4zjzA-3eqnA:
undetectable		 4zjzA-3eqnA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 4 LEU A 554
ILE A 502
GLY A 592
ILE A 526
 None
 0.77A 5dzk3-3eqnA:
undetectable
5dzkm-3eqnA:
undetectable		 5dzk3-3eqnA:
1.60
5dzkm-3eqnA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 ILE A 502
GLY A 592
ILE A 526
LEU A 554
 None
 0.74A 5dzkB-3eqnA:
undetectable
5dzkI-3eqnA:
undetectable
5dzkW-3eqnA:
undetectable		 5dzkB-3eqnA:
13.53
5dzkI-3eqnA:
13.33
5dzkW-3eqnA:
1.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 ILE A 502
GLY A 592
ILE A 526
LEU A 554
 None
 0.77A 5dzki-3eqnA:
undetectable
5dzkj-3eqnA:
undetectable
5dzkx-3eqnA:
undetectable		 5dzki-3eqnA:
13.33
5dzkj-3eqnA:
13.33
5dzkx-3eqnA:
1.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 ILE A 502
GLY A 592
ILE A 526
LEU A 554
 None
 0.71A 5dzkd-3eqnA:
undetectable
5dzkk-3eqnA:
undetectable
5dzky-3eqnA:
undetectable		 5dzkd-3eqnA:
13.53
5dzkk-3eqnA:
13.33
5dzky-3eqnA:
1.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 4 ILE A 502
GLY A 592
ILE A 526
LEU A 554
 None
 0.71A 5dzkl-3eqnA:
undetectable
5dzkz-3eqnA:
undetectable		 5dzkl-3eqnA:
13.33
5dzkz-3eqnA:
1.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 ALA A 630
THR A 721
GLN A 696
PHE A 681
GLU A 633
 None
None
None
None
GOL  A 765 ( 3.0A)
 1.37A 5hfjG-3eqnA:
undetectable		 5hfjG-3eqnA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 7 VAL A 229
ILE A 283
CYH A 259
PHE A 222
 None
 0.92A 5hieC-3eqnA:
undetectable		 5hieC-3eqnA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 GLU A 610
GLY A 206
SER A 204
GLY A 203
 GOL  A 764 (-2.8A)
None
GOL  A 764 (-3.5A)
None
 1.05A 5kprA-3eqnA:
undetectable		 5kprA-3eqnA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 4 GLN A 292
THR A 291
THR A 337
LEU A 332
 None
 0.85A 5m5kA-3eqnA:
undetectable		 5m5kA-3eqnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 4 GLN A 292
THR A 291
THR A 337
LEU A 332
 None
 0.84A 5m5kC-3eqnA:
undetectable		 5m5kC-3eqnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 4 GLN A 292
THR A 291
THR A 337
LEU A 332
 None
 0.85A 5m66B-3eqnA:
undetectable		 5m66B-3eqnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		3 / 3 THR A 291
THR A 337
LEU A 332
 None
 0.66A 5m66D-3eqnA:
undetectable		 5m66D-3eqnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 8 ASN A 224
GLU A 281
TRP A 245
TRP A 247
 None
 1.31A 5oh1C-3eqnA:
undetectable		 5oh1C-3eqnA:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 6 PHE A 418
VAL A 417
ALA A 422
THR A   4
 None
 1.05A 5t7bA-3eqnA:
undetectable		 5t7bA-3eqnA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		3 / 3 GLY A 678
VAL A 703
MET A 666
 None
 0.60A 5ycpA-3eqnA:
undetectable		 5ycpA-3eqnA:
7.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		3 / 3 GLU A 485
ASP A 509
PRO A 510
 None
 0.75A 6berA-3eqnA:
undetectable		 6berA-3eqnA:
1.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 SER A 609
VAL A 668
VAL A 676
GLY A 628
PHE A 681
 None
 1.20A 6bqgA-3eqnA:
undetectable		 6bqgA-3eqnA:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 8 ILE A 674
VAL A 676
ALA A 630
THR A 607
 None
 0.90A 6cduD-3eqnA:
undetectable
6cduE-3eqnA:
undetectable		 6cduD-3eqnA:
17.63
6cduE-3eqnA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 11 VAL A 153
VAL A 101
PHE A  89
GLN A  64
VAL A  87
 None
 1.14A 6dryA-3eqnA:
undetectable		 6dryA-3eqnA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 9 LEU A 208
GLY A 219
ILE A 241
PHE A 234
PHE A 227
 None
 1.20A 6ebpA-3eqnA:
undetectable		 6ebpA-3eqnA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EUQ_A_DXCA502_0
(MULTIDRUG
TRANSPORTER MDFA)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 11 ASN A 148
ASP A 133
GLY A 581
PRO A 134
GLN A  83
 None
 1.23A 6euqA-3eqnA:
undetectable		 6euqA-3eqnA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_A_ADNA501_2
(-)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 GLN A 292
THR A 291
THR A 337
LEU A 332
 None
 0.86A 6gbnA-3eqnA:
undetectable		 6gbnA-3eqnA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBN_D_ADND501_2
(-)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		4 / 5 GLN A 292
THR A 291
THR A 337
LEU A 332
 None
 0.87A 6gbnD-3eqnA:
undetectable		 6gbnD-3eqnA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_1
(-)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 12 THR A 433
GLY A 432
VAL A 397
THR A 529
GLY A 527
 None
 1.18A 6gngA-3eqnA:
undetectable		 6gngA-3eqnA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 3eqn GLUCAN
1,3-BETA-GLUCOSIDASE
(Phanerochaete
chrysosporium) 		5 / 11 ILE A 526
LEU A 573
THR A 632
MET A 595
LEU A 554
 None
 1.47A 6hupA-3eqnA:
undetectable
6hupB-3eqnA:
undetectable		 6hupA-3eqnA:
6.78
6hupB-3eqnA:
6.53