SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3er6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 ALA A 113
ILE A  80
LEU A  90
PHE A 142
MET A 134
 None
 1.05A 1dtlA-3er6A:
undetectable		 1dtlA-3er6A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 LEU A  14
VAL A 120
GLY A 117
LEU A  97
 None
 0.75A 1jlbA-3er6A:
undetectable		 1jlbA-3er6A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_H_BO2H1400_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 11 SER A  23
ALA A  22
ALA A 113
GLY A 117
THR A 116
 None
 1.04A 2f16H-3er6A:
undetectable
2f16I-3er6A:
undetectable		 2f16H-3er6A:
22.13
2f16I-3er6A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 11 SER A  23
ALA A  22
ALA A 113
GLY A 117
THR A 116
 None
 1.04A 2f16V-3er6A:
undetectable
2f16W-3er6A:
undetectable		 2f16V-3er6A:
22.13
2f16W-3er6A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 SER A 174
SER A 166
VAL A 175
SER A 171
 None
 1.45A 2j9cA-3er6A:
undetectable
2j9cB-3er6A:
undetectable
2j9cC-3er6A:
undetectable		 2j9cA-3er6A:
22.27
2j9cB-3er6A:
22.27
2j9cC-3er6A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OBV_A_SAMA501_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.06A 2obvA-3er6A:
undetectable		 2obvA-3er6A:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P02_A_SAMA2_0
(S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-2)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.09A 2p02A-3er6A:
undetectable		 2p02A-3er6A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 125
ALA A 124
ILE A  93
ILE A 118
ILE A 101
 None
 0.82A 3k4vA-3er6A:
undetectable		 3k4vA-3er6A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 125
ALA A 124
ILE A  93
ILE A 118
ILE A 101
 None
 0.83A 3k4vB-3er6A:
undetectable		 3k4vB-3er6A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 ASN A  76
ASN A 162
GLU A 182
 None
 0.78A 3kpdC-3er6A:
undetectable		 3kpdC-3er6A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 ASN A  76
ASN A 162
GLU A 182
 None
 0.93A 3kpdB-3er6A:
undetectable		 3kpdB-3er6A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_V_BO2V1401_1
(PROTEASOME COMPONENT
PUP1
PROTEASOME COMPONENT
PUP3)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 11 SER A  23
ALA A  22
ALA A 113
GLY A 117
THR A 116
 None
 1.05A 3mg0V-3er6A:
undetectable
3mg0W-3er6A:
undetectable		 3mg0V-3er6A:
22.13
3mg0W-3er6A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 11 GLY A 125
ALA A 124
ILE A  93
ILE A 118
ILE A 101
 None
 0.87A 3ndxB-3er6A:
undetectable		 3ndxB-3er6A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 GLY A 125
ALA A 124
ILE A  93
ILE A 118
ILE A 101
 None
 0.87A 3tl9A-3er6A:
undetectable		 3tl9A-3er6A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 11 LEU A 127
LEU A 145
PHE A 119
PRO A 147
ALA A 132
 None
 1.41A 4hwkB-3er6A:
undetectable		 4hwkB-3er6A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 LEU A 127
LEU A 145
PHE A 119
PRO A 147
ALA A 132
 None
 1.42A 4hwkC-3er6A:
undetectable		 4hwkC-3er6A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 11 LEU A 127
LEU A 145
PHE A 119
PRO A 147
ALA A 132
 None
 1.44A 4hwkD-3er6A:
5.0		 4hwkD-3er6A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.12A 4kttA-3er6A:
undetectable		 4kttA-3er6A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.07A 4kttC-3er6A:
undetectable		 4kttC-3er6A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.10A 4ndnA-3er6A:
undetectable		 4ndnA-3er6A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.09A 4ndnC-3er6A:
undetectable		 4ndnC-3er6A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_1
(PROTEASE)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		5 / 11 GLY A 168
ILE A  83
GLY A  81
ILE A  79
ILE A 118
 None
 1.01A 4njvC-3er6A:
undetectable		 4njvC-3er6A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.05A 4odjA-3er6A:
undetectable		 4odjA-3er6A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_ADNA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.10A 5a1iA-3er6A:
undetectable		 5a1iA-3er6A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1I_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.10A 5a1iA-3er6A:
undetectable		 5a1iA-3er6A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 TYR A  20
THR A 116
THR A  17
 None
 0.82A 5aoxE-3er6A:
undetectable		 5aoxE-3er6A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_A_ACTA404_0
(L-LYSINE
3-HYDROXYLASE)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 6 ILE A  79
LEU A  31
VAL A 112
SER A  27
 None
 1.27A 6f6jA-3er6A:
undetectable		 6f6jA-3er6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.13A 6fbnB-3er6A:
undetectable		 6fbnB-3er6A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBO_A_ADNA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.09A 6fboA-3er6A:
undetectable		 6fboA-3er6A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCB_A_SAMA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.10A 6fcbA-3er6A:
undetectable		 6fcbA-3er6A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FCD_A_ADNA405_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 8 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.08A 6fcdA-3er6A:
undetectable		 6fcdA-3er6A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G6R_A_SAMA406_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3er6 PUTATIVE
TRANSCRIPTIONAL
REGULATOR PROTEIN
(Vibrio
parahaemolyticus) 		4 / 7 HIS A 135
PRO A 169
ASP A 115
SER A  89
 None
 1.10A 6g6rA-3er6A:
undetectable		 6g6rA-3er6A:
19.40