SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3erv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_D_DIFD3701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3erv PUTATIVE C39-LIKE
PEPTIDASE
(Bacillus
anthracis) 		5 / 10 VAL A 246
LEU A  56
GLY A 164
ALA A 163
SER A 160
 None
 1.18A 1pxxD-3ervA:
undetectable		 1pxxD-3ervA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 3erv PUTATIVE C39-LIKE
PEPTIDASE
(Bacillus
anthracis) 		5 / 12 VAL A 167
ILE A 169
PHE A 231
ILE A 154
VAL A 161
 None
 0.95A 1qhsA-3ervA:
undetectable		 1qhsA-3ervA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 3erv PUTATIVE C39-LIKE
PEPTIDASE
(Bacillus
anthracis) 		5 / 12 VAL A 167
ILE A 169
PHE A 231
ILE A 154
VAL A 161
 None
 0.95A 1qhyA-3ervA:
undetectable		 1qhyA-3ervA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_C_ADNC302_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 3erv PUTATIVE C39-LIKE
PEPTIDASE
(Bacillus
anthracis) 		5 / 12 HIS A 131
GLY A 109
TYR A 127
GLY A 114
VAL A 193
 None
 1.12A 3f8wC-3ervA:
undetectable		 3f8wC-3ervA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3erv PUTATIVE C39-LIKE
PEPTIDASE
(Bacillus
anthracis) 		5 / 12 LEU A 134
LEU A 137
ALA A 138
MET A  80
LEU A  81
 None
 1.12A 3olsA-3ervA:
undetectable		 3olsA-3ervA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3erv PUTATIVE C39-LIKE
PEPTIDASE
(Bacillus
anthracis) 		4 / 5 TYR A 245
VAL A 167
SER A 244
GLY A 164
 None
 1.48A 3v4tA-3ervA:
undetectable
3v4tD-3ervA:
undetectable		 3v4tA-3ervA:
23.21
3v4tD-3ervA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3erv PUTATIVE C39-LIKE
PEPTIDASE
(Bacillus
anthracis) 		4 / 8 TYR A 207
VAL A 212
ILE A 214
GLU A 155
 None
 1.11A 4a97C-3ervA:
undetectable		 4a97C-3ervA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 3erv PUTATIVE C39-LIKE
PEPTIDASE
(Bacillus
anthracis) 		5 / 12 LEU A 134
LEU A 137
ALA A 138
MET A  80
THR A 150
 None
 1.20A 4fn9B-3ervA:
undetectable		 4fn9B-3ervA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 3erv PUTATIVE C39-LIKE
PEPTIDASE
(Bacillus
anthracis) 		3 / 3 ALA A 138
GLN A 241
GLY A 239
 None
 0.58A 4odoC-3ervA:
undetectable		 4odoC-3ervA:
25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 3erv PUTATIVE C39-LIKE
PEPTIDASE
(Bacillus
anthracis) 		4 / 7 PHE A 175
ILE A 214
ASP A 208
PHE A 231
 None
 0.86A 5h3aA-3ervA:
undetectable		 5h3aA-3ervA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 3erv PUTATIVE C39-LIKE
PEPTIDASE
(Bacillus
anthracis) 		4 / 7 ASN A  95
THR A  75
ILE A 119
GLY A  71
 None
None
EDO  A   1 (-3.9A)
None
 0.95A 5nzyA-3ervA:
undetectable		 5nzyA-3ervA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 3erv PUTATIVE C39-LIKE
PEPTIDASE
(Bacillus
anthracis) 		6 / 12 LEU A 134
LEU A 137
ALA A 138
MET A  80
LEU A  81
ILE A 170
 None
 1.10A 5toaA-3ervA:
undetectable		 5toaA-3ervA:
21.48