SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3erw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3erw SPORULATION
THIOL-DISULFIDE
OXIDOREDUCTASE A
(Bacillus
subtilis) 		4 / 5 PHE A  75
PHE A 115
LEU A 113
PHE A 107
 None
 1.25A 2y69C-3erwA:
undetectable
2y69J-3erwA:
undetectable		 2y69C-3erwA:
16.48
2y69J-3erwA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3erw SPORULATION
THIOL-DISULFIDE
OXIDOREDUCTASE A
(Bacillus
subtilis) 		4 / 5 PHE A  75
PHE A 115
LEU A 113
PHE A 107
 None
 1.18A 2y69P-3erwA:
undetectable
2y69W-3erwA:
undetectable		 2y69P-3erwA:
16.48
2y69W-3erwA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3erw SPORULATION
THIOL-DISULFIDE
OXIDOREDUCTASE A
(Bacillus
subtilis) 		4 / 5 PHE A  75
PHE A 115
LEU A 113
PHE A 107
 None
 1.24A 3abmC-3erwA:
undetectable
3abmJ-3erwA:
undetectable		 3abmC-3erwA:
16.48
3abmJ-3erwA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3erw SPORULATION
THIOL-DISULFIDE
OXIDOREDUCTASE A
(Bacillus
subtilis) 		4 / 5 PHE A  75
PHE A 115
LEU A 113
PHE A 107
 None
 1.22A 3abmP-3erwA:
undetectable
3abmW-3erwA:
undetectable		 3abmP-3erwA:
16.48
3abmW-3erwA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3erw SPORULATION
THIOL-DISULFIDE
OXIDOREDUCTASE A
(Bacillus
subtilis) 		4 / 5 PHE A  75
PHE A 115
LEU A 113
PHE A 107
 None
 1.29A 3ag3C-3erwA:
undetectable
3ag3J-3erwA:
undetectable		 3ag3C-3erwA:
16.48
3ag3J-3erwA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_A_BEZA302_0
(DISULFIDE
INTERCHANGE PROTEIN)		 3erw SPORULATION
THIOL-DISULFIDE
OXIDOREDUCTASE A
(Bacillus
subtilis) 		4 / 6 PRO A 135
HIS A  59
LEU A  72
PRO A 153
 None
 1.32A 3gv1A-3erwA:
6.1
3gv1C-3erwA:
5.9		 3gv1A-3erwA:
21.69
3gv1C-3erwA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_B_EPAB1_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3erw SPORULATION
THIOL-DISULFIDE
OXIDOREDUCTASE A
(Bacillus
subtilis) 		5 / 7 PHE A  60
VAL A  92
VAL A  90
LEU A  89
VAL A  87
 None
 1.34A 3hs6B-3erwA:
undetectable		 3hs6B-3erwA:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 3erw SPORULATION
THIOL-DISULFIDE
OXIDOREDUCTASE A
(Bacillus
subtilis) 		4 / 8 PHE A 107
ILE A  42
LEU A  72
PHE A 115
 None
 1.06A 3rqwI-3erwA:
undetectable
3rqwJ-3erwA:
undetectable		 3rqwI-3erwA:
17.65
3rqwJ-3erwA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3erw SPORULATION
THIOL-DISULFIDE
OXIDOREDUCTASE A
(Bacillus
subtilis) 		4 / 5 PHE A  75
PHE A 115
LEU A 113
PHE A 107
 None
 1.33A 5wauC-3erwA:
undetectable
5wauJ-3erwA:
undetectable		 5wauC-3erwA:
16.48
5wauJ-3erwA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3erw SPORULATION
THIOL-DISULFIDE
OXIDOREDUCTASE A
(Bacillus
subtilis) 		4 / 5 PHE A  75
PHE A 115
LEU A 113
PHE A 107
 None
 1.32A 5wauc-3erwA:
undetectable
5wauj-3erwA:
undetectable		 5wauc-3erwA:
16.48
5wauj-3erwA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3erw SPORULATION
THIOL-DISULFIDE
OXIDOREDUCTASE A
(Bacillus
subtilis) 		4 / 5 PHE A  75
PHE A 115
LEU A 113
PHE A 107
 None
 1.22A 5xdqC-3erwA:
undetectable
5xdqJ-3erwA:
undetectable		 5xdqC-3erwA:
16.48
5xdqJ-3erwA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3erw SPORULATION
THIOL-DISULFIDE
OXIDOREDUCTASE A
(Bacillus
subtilis) 		4 / 5 PHE A  75
PHE A 115
LEU A 113
PHE A 107
 None
 1.25A 5xdqP-3erwA:
undetectable
5xdqW-3erwA:
undetectable		 5xdqP-3erwA:
16.48
5xdqW-3erwA:
17.24