SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3es2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 3es2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 6 GLY A 271
TYR A 196
ALA A 205
TYR A 207
 None
 0.93A 1dmaB-3es2A:
undetectable		 1dmaB-3es2A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3es2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 ASP A 210
VAL A 211
GLY A 191
ASP A 382
 None
 1.21A 3w9tA-3es2A:
undetectable		 3w9tA-3es2A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 3es2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 ASP A 210
VAL A 211
GLY A 191
ASP A 382
 None
 1.21A 3w9tB-3es2A:
undetectable		 3w9tB-3es2A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3es2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 ASP A 210
VAL A 211
GLY A 191
ASP A 382
 None
 1.21A 3w9tC-3es2A:
undetectable		 3w9tC-3es2A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 3es2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 ASP A 210
VAL A 211
GLY A 191
ASP A 382
 None
 1.22A 3w9tD-3es2A:
undetectable		 3w9tD-3es2A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 3es2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 ASP A 210
VAL A 211
GLY A 191
ASP A 382
 None
 1.22A 3w9tE-3es2A:
undetectable		 3w9tE-3es2A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 3es2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 ASP A 210
VAL A 211
GLY A 191
ASP A 382
 None
 1.22A 3w9tF-3es2A:
undetectable		 3w9tF-3es2A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 3es2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 5 ASP A 210
VAL A 211
GLY A 191
ASP A 382
 None
 1.22A 3w9tG-3es2A:
undetectable		 3w9tG-3es2A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BJC_A_RPBA2162_1
(TANKYRASE-2)		 3es2 PROBABLE
TWO-COMPONENT
RESPONSE REGULATOR
(Pseudomonas
aeruginosa) 		4 / 8 GLY A 271
TYR A 196
ALA A 205
TYR A 207
 None
 0.89A 4bjcA-3es2A:
undetectable		 4bjcA-3es2A:
24.31