SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3esi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OIP_A_MTXA605_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3esi	UNCHARACTERIZED PROTEIN (Pectobacterium atrosepticum)	5 / 12	ALA A 56 LEU A 119 PHE A 99 SER A 114 ILE A 69	None	1.07A	2oipA-3esiA: undetectable	2oipA-3esiA: 12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADS_B_IMNB3_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3esi	UNCHARACTERIZED PROTEIN (Pectobacterium atrosepticum)	5 / 12	GLY A 45 SER A 113 LEU A 84 LEU A 24 VAL A 26	None	1.28A	3adsB-3esiA: undetectable	3adsB-3esiA: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_A_MTXA605_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3esi	UNCHARACTERIZED PROTEIN (Pectobacterium atrosepticum)	5 / 12	ALA A 56 LEU A 119 PHE A 99 SER A 114 ILE A 69	None	1.17A	3hj3A-3esiA: undetectable	3hj3A-3esiA: 12.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HJ3_B_MTXB609_1 (CHAIN A, CRYSTAL STRUCTURE OF DHFR)	3esi	UNCHARACTERIZED PROTEIN (Pectobacterium atrosepticum)	5 / 12	ALA A 56 LEU A 119 PHE A 99 SER A 114 ILE A 69	None	1.06A	3hj3B-3esiA: undetectable	3hj3B-3esiA: 12.87

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OIP_A_MTXA605_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","3esi","UNCHARACTERIZED PROTEIN","Pectobacterium atrosepticum",5,"ALA A  56;LEU A 119;PHE A  99;SER A 114;ILE A  69","None","1.07A","2oipA-3esiA:undetectable","2oipA-3esiA:12.52"],["3ADS_B_IMNB3_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","3esi","UNCHARACTERIZED PROTEIN","Pectobacterium atrosepticum",5,"GLY A  45;SER A 113;LEU A  84;LEU A  24;VAL A  26","None","1.28A","3adsB-3esiA:undetectable","3adsB-3esiA:17.86"],["3HJ3_A_MTXA605_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","3esi","UNCHARACTERIZED PROTEIN","Pectobacterium atrosepticum",5,"ALA A  56;LEU A 119;PHE A  99;SER A 114;ILE A  69","None","1.17A","3hj3A-3esiA:undetectable","3hj3A-3esiA:12.87"],["3HJ3_B_MTXB609_1","CHAIN A, CRYSTAL STRUCTURE OF DHFR","3esi","UNCHARACTERIZED PROTEIN","Pectobacterium atrosepticum",5,"ALA A  56;LEU A 119;PHE A  99;SER A 114;ILE A  69","None","1.06A","3hj3B-3esiA:undetectable","3hj3B-3esiA:12.87"]]