SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3esm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1G5Y_C_9CRC502_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3esm	UNCHARACTERIZED PROTEIN (Nocardia farcinica)	5 / 10	ALA A 81 SER A 70 LEU A 65 ALA A 91 PHE A 113	None SO4 A 1 (-2.6A) None None None	1.13A	1g5yC-3esmA: undetectable	1g5yC-3esmA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BDM_A_TMIA503_1 (CYTOCHROME P450 2B4)	3esm	UNCHARACTERIZED PROTEIN (Nocardia farcinica)	4 / 8	ARG A 69 LEU A 162 VAL A 126 VAL A 68	None	1.00A	2bdmA-3esmA: undetectable	2bdmA-3esmA: 14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RR3_A_FLRA700_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3esm	UNCHARACTERIZED PROTEIN (Nocardia farcinica)	5 / 12	VAL A 126 VAL A 45 GLY A 36 ALA A 37 LEU A 120	None	1.03A	3rr3A-3esmA: undetectable	3rr3A-3esmA: 13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RR3_B_FLRB700_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3esm	UNCHARACTERIZED PROTEIN (Nocardia farcinica)	5 / 12	VAL A 126 VAL A 45 GLY A 36 ALA A 37 LEU A 120	None	1.04A	3rr3B-3esmA: undetectable	3rr3B-3esmA: 13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PH9_A_IBPA601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3esm	UNCHARACTERIZED PROTEIN (Nocardia farcinica)	5 / 10	VAL A 126 VAL A 45 GLY A 36 ALA A 37 LEU A 120	None	1.10A	4ph9A-3esmA: undetectable	4ph9A-3esmA: 13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PH9_B_IBPB601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	3esm	UNCHARACTERIZED PROTEIN (Nocardia farcinica)	5 / 10	VAL A 126 VAL A 45 GLY A 36 ALA A 37 LEU A 120	None	1.10A	4ph9B-3esmA: undetectable	4ph9B-3esmA: 13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IKT_A_TLFA601_0 (PROSTAGLANDIN G/H SYNTHASE 2)	3esm	UNCHARACTERIZED PROTEIN (Nocardia farcinica)	5 / 12	VAL A 126 VAL A 45 GLY A 36 ALA A 37 LEU A 120	None	1.08A	5iktA-3esmA: undetectable	5iktA-3esmA: 12.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1G5Y_C_9CRC502_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3esm","UNCHARACTERIZED PROTEIN","Nocardia farcinica",5,"ALA A  81;SER A  70;LEU A  65;ALA A  91;PHE A 113","None;SO4 A   1 (-2.6A);None;None;None","1.13A","1g5yC-3esmA:undetectable","1g5yC-3esmA:20.60"],["2BDM_A_TMIA503_1","CYTOCHROME P450 2B4","3esm","UNCHARACTERIZED PROTEIN","Nocardia farcinica",4,"ARG A  69;LEU A 162;VAL A 126;VAL A  68","None","1.00A","2bdmA-3esmA:undetectable","2bdmA-3esmA:14.44"],["3RR3_A_FLRA700_1","PROSTAGLANDIN G\/H SYNTHASE 2","3esm","UNCHARACTERIZED PROTEIN","Nocardia farcinica",5,"VAL A 126;VAL A  45;GLY A  36;ALA A  37;LEU A 120","None","1.03A","3rr3A-3esmA:undetectable","3rr3A-3esmA:13.00"],["3RR3_B_FLRB700_1","PROSTAGLANDIN G\/H SYNTHASE 2","3esm","UNCHARACTERIZED PROTEIN","Nocardia farcinica",5,"VAL A 126;VAL A  45;GLY A  36;ALA A  37;LEU A 120","None","1.04A","3rr3B-3esmA:undetectable","3rr3B-3esmA:13.00"],["4PH9_A_IBPA601_1","PROSTAGLANDIN G\/H SYNTHASE 2","3esm","UNCHARACTERIZED PROTEIN","Nocardia farcinica",5,"VAL A 126;VAL A  45;GLY A  36;ALA A  37;LEU A 120","None","1.10A","4ph9A-3esmA:undetectable","4ph9A-3esmA:13.00"],["4PH9_B_IBPB601_1","PROSTAGLANDIN G\/H SYNTHASE 2","3esm","UNCHARACTERIZED PROTEIN","Nocardia farcinica",5,"VAL A 126;VAL A  45;GLY A  36;ALA A  37;LEU A 120","None","1.10A","4ph9B-3esmA:undetectable","4ph9B-3esmA:13.00"],["5IKT_A_TLFA601_0","PROSTAGLANDIN G\/H SYNTHASE 2","3esm","UNCHARACTERIZED PROTEIN","Nocardia farcinica",5,"VAL A 126;VAL A  45;GLY A  36;ALA A  37;LEU A 120","None","1.08A","5iktA-3esmA:undetectable","5iktA-3esmA:12.95"]]