SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3esr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 3esr D,D-HEPTOSE
1,7-BISPHOSPHATE
PHOSPHATASE
(Escherichia
coli) 		5 / 12 ASP A  33
ASP A  39
GLY A 155
VAL A 154
ILE A  52
 PO4  A 214 ( 3.9A)
None
None
None
None
 1.03A 2f8gA-3esrA:
undetectable		 2f8gA-3esrA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 3esr D,D-HEPTOSE
1,7-BISPHOSPHATE
PHOSPHATASE
(Escherichia
coli) 		3 / 3 CYH A 112
CYH A 127
HIS A 114
 ZN  A 212 (-2.2A)
ZN  A 212 (-2.4A)
ZN  A 212 (-3.4A)
 0.86A 2iwkA-3esrA:
undetectable		 2iwkA-3esrA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 3esr D,D-HEPTOSE
1,7-BISPHOSPHATE
PHOSPHATASE
(Escherichia
coli) 		3 / 3 CYH A 112
CYH A 127
HIS A 114
 ZN  A 212 (-2.2A)
ZN  A 212 (-2.4A)
ZN  A 212 (-3.4A)
 0.86A 2iwkB-3esrA:
undetectable		 2iwkB-3esrA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_B_CUB1022_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3esr D,D-HEPTOSE
1,7-BISPHOSPHATE
PHOSPHATASE
(Escherichia
coli) 		3 / 3 CYH A 112
CYH A 127
HIS A 114
 ZN  A 212 (-2.2A)
ZN  A 212 (-2.4A)
ZN  A 212 (-3.4A)
 0.72A 3dtuB-3esrA:
undetectable		 3dtuB-3esrA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_D_CUD3_0
(CYTOCHROME C OXIDASE
SUBUNIT 2)		 3esr D,D-HEPTOSE
1,7-BISPHOSPHATE
PHOSPHATASE
(Escherichia
coli) 		3 / 3 CYH A 112
CYH A 127
HIS A 114
 ZN  A 212 (-2.2A)
ZN  A 212 (-2.4A)
ZN  A 212 (-3.4A)
 0.70A 3dtuD-3esrA:
undetectable		 3dtuD-3esrA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_D_NCAD302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 3esr D,D-HEPTOSE
1,7-BISPHOSPHATE
PHOSPHATASE
(Escherichia
coli) 		4 / 7 LEU A 144
ALA A  27
ASP A 107
TYR A 110
 None
 1.10A 3rodD-3esrA:
undetectable		 3rodD-3esrA:
27.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3esr D,D-HEPTOSE
1,7-BISPHOSPHATE
PHOSPHATASE
(Escherichia
coli) 		5 / 10 LEU A 199
TYR A 152
GLY A 155
TRP A 191
LEU A 193
 None
 1.45A 6bsgA-3esrA:
undetectable		 6bsgA-3esrA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 3esr D,D-HEPTOSE
1,7-BISPHOSPHATE
PHOSPHATASE
(Escherichia
coli) 		5 / 12 ASP A  33
ASP A  39
GLY A 155
VAL A 154
ILE A  52
 PO4  A 214 ( 3.9A)
None
None
None
None
 0.96A 6dh6A-3esrA:
undetectable		 6dh6A-3esrA:
16.67