SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3esu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
4 / 7 GLN F1006
SER F1007
TYR F1090
GLN F  38
None
1.49A 1eiiA-3esuF:
undetectable
1eiiA-3esuF:
18.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
8 / 12 TYR F  36
GLN F  89
PHE F  98
TRP F1033
ASN F1035
VAL F1037
ALA F1093
TRP F1103
None
0.67A 1h8sA-3esuF:
32.1
1h8sA-3esuF:
70.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
5 / 7 GLY F1053
PRO F1052
THR F1057
ILE F1051
GLY F1055
None
1.09A 1usqA-3esuF:
undetectable
1usqA-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_B_CLMB1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
4 / 6 GLY F1053
PRO F1052
ILE F1051
GLY F1055
None
0.81A 1usqB-3esuF:
undetectable
1usqB-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
4 / 6 GLY F1053
PRO F1052
ILE F1051
GLY F1055
None
0.80A 1usqC-3esuF:
undetectable
1usqC-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
4 / 6 GLY F1053
PRO F1052
ILE F1051
GLY F1055
None
0.81A 1usqD-3esuF:
undetectable
1usqD-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
4 / 6 GLY F1053
PRO F1052
ILE F1051
GLY F1055
None
0.81A 1usqE-3esuF:
undetectable
1usqE-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
5 / 7 GLY F1053
PRO F1052
THR F1057
ILE F1051
GLY F1055
None
1.08A 1usqF-3esuF:
undetectable
1usqF-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
5 / 7 GLY F1053
PRO F1052
THR F1057
ILE F1051
GLY F1055
None
1.11A 2jkjE-3esuF:
undetectable
2jkjE-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
5 / 7 GLY F1053
PRO F1052
THR F1057
ILE F1051
GLY F1055
None
1.11A 2jklA-3esuF:
undetectable
2jklA-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
5 / 7 GLY F1053
PRO F1052
THR F1057
ILE F1051
GLY F1055
None
1.12A 2jklC-3esuF:
undetectable
2jklC-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
5 / 7 GLY F1053
PRO F1052
THR F1057
ILE F1051
GLY F1055
None
1.11A 2jklD-3esuF:
undetectable
2jklD-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
5 / 7 GLY F1053
PRO F1052
THR F1057
ILE F1051
GLY F1055
None
1.12A 2jklE-3esuF:
undetectable
2jklE-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
5 / 7 GLY F1053
PRO F1052
THR F1057
ILE F1051
GLY F1055
None
1.11A 2jklF-3esuF:
undetectable
2jklF-3esuF:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
3 / 3 GLU F 105
GLY F  84
THR F  85
None
0.56A 3iazA-3esuF:
undetectable
3iazA-3esuF:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)
3esu ANTIBODY 14B7* LIGHT
CHAIN AND ANTIBODY
14B7* HEAVY CHAIN
LINKED WITH A
SYNTHETIC (GGGGS)4
LINKER

(Mus
musculus)
5 / 12 TRP F1033
GLN F  89
GLN F  90
GLY F  91
LEU F  94
None
0.68A 4uilH-3esuF:
14.8
4uilL-3esuF:
20.9
4uilH-3esuF:
26.52
4uilL-3esuF:
52.40