SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3et6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 3et6 SOLUBLE GUANYLYL
CYCLASE BETA
(Chlamydomonas
reinhardtii) 		4 / 8 LEU A 547
VAL A 572
GLY A 573
LEU A 551
 None
 0.84A 1jlbA-3et6A:
4.9		 1jlbA-3et6A:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_2
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 3et6 SOLUBLE GUANYLYL
CYCLASE BETA
(Chlamydomonas
reinhardtii) 		4 / 4 VAL A 531
ARG A 552
ILE A 570
THR A 477
 None
 1.24A 3cl9A-3et6A:
undetectable		 3cl9A-3et6A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA605_0
(ALPHA-AMYLASE)		 3et6 SOLUBLE GUANYLYL
CYCLASE BETA
(Chlamydomonas
reinhardtii) 		4 / 8 GLY A 485
ILE A 489
ASP A 482
ASP A 527
 PO4  A   2 (-3.4A)
None
None
None
 0.92A 6ag0A-3et6A:
undetectable		 6ag0A-3et6A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC605_0
(ALPHA-AMYLASE)		 3et6 SOLUBLE GUANYLYL
CYCLASE BETA
(Chlamydomonas
reinhardtii) 		4 / 8 GLY A 485
ILE A 489
ASP A 482
ASP A 527
 PO4  A   2 (-3.4A)
None
None
None
 0.94A 6ag0C-3et6A:
undetectable		 6ag0C-3et6A:
16.13