SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3etl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3etl DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
maripaludis) 		5 / 12 ILE A 209
ILE A  95
LEU A  91
PHE A 286
LEU A 288
 None
 1.16A 2qo5A-3etlA:
undetectable		 2qo5A-3etlA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3etl DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
maripaludis) 		5 / 12 ILE A 209
ILE A  95
THR A  82
LEU A  91
PHE A 286
 None
 1.01A 2qo5A-3etlA:
undetectable		 2qo5A-3etlA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 3etl DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
maripaludis) 		4 / 6 LEU A  87
LEU A  91
ASP A  88
ILE A 320
 None
 1.03A 2rlfA-3etlA:
undetectable
2rlfB-3etlA:
undetectable		 2rlfA-3etlA:
9.88
2rlfB-3etlA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 3etl DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
maripaludis) 		4 / 6 LEU A  87
LEU A  91
ASP A  88
ILE A 320
 None
 1.01A 2rlfB-3etlA:
undetectable
2rlfC-3etlA:
undetectable		 2rlfB-3etlA:
9.88
2rlfC-3etlA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_D_ADND500_2
(ADENOSYLHOMOCYSTEINA
SE)		 3etl DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
maripaludis) 		4 / 5 LEU A 253
GLN A 117
THR A 118
LEU A 288
 None
 1.12A 3ce6D-3etlA:
undetectable		 3ce6D-3etlA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3etl DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
maripaludis) 		3 / 3 THR A 283
SER A  99
PHE A 103
 None
MG  A 502 ( 4.1A)
None
 0.77A 3d4sA-3etlA:
undetectable		 3d4sA-3etlA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 3etl DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
maripaludis) 		4 / 7 GLY A 165
ALA A 166
GLY A  83
ILE A 320
 None
 0.59A 5kqyB-3etlA:
undetectable		 5kqyB-3etlA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 3etl DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
maripaludis) 		4 / 8 GLY A 165
ALA A 166
GLY A  83
ILE A 320
 None
 0.60A 5kr1B-3etlA:
undetectable		 5kr1B-3etlA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 3etl DNA REPAIR AND
RECOMBINATION
PROTEIN RADA
(Methanococcus
maripaludis) 		5 / 12 ALA A 245
VAL A 208
ILE A 195
VAL A 254
VAL A 252
 None
 0.93A 6dh0A-3etlA:
undetectable		 6dh0A-3etlA:
16.46