SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3etn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DDS_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.11A 1ddsA-3etnA:
undetectable		 1ddsA-3etnA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.10A 1dyiA-3etnA:
undetectable		 1dyiA-3etnA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYI_B_FOLB161_0
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.10A 1dyiB-3etnA:
2.0		 1dyiB-3etnA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FAP_A_RAPA108_1
(FK506-BINDING
PROTEIN)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 GLN A  14
VAL A  16
ILE A  19
ILE A  94
ILE A 122
 None
 0.92A 1fapA-3etnA:
undetectable		 1fapA-3etnA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		4 / 8 ALA A  28
ASP A 165
ILE A 166
ILE A  19
 None
 0.92A 1rg9A-3etnA:
undetectable		 1rg9A-3etnA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_A_SALA1341_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		4 / 8 LEU A  43
THR A 171
VAL A 168
ALA A  28
 None
 0.96A 3ax9A-3etnA:
undetectable		 3ax9A-3etnA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_B_SAMB220_0
(16S RRNA METHYLASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 GLY A 124
PRO A 143
ALA A  15
LEU A 138
THR A 158
 None
 1.06A 3mteB-3etnA:
undetectable		 3mteB-3etnA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_A_SAMA405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		4 / 8 ALA A  28
ASP A 165
ILE A 166
ILE A  19
 None
 0.88A 4kttB-3etnA:
undetectable		 4kttB-3etnA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTT_C_SAMC404_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		4 / 8 ALA A  28
ASP A 165
ILE A 166
ILE A  19
 None
 0.88A 4kttD-3etnA:
undetectable		 4kttD-3etnA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		4 / 8 ALA A  28
ASP A 165
ILE A 166
ILE A  19
 None
 0.92A 4ndnB-3etnA:
undetectable		 4ndnB-3etnA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		4 / 8 ALA A  28
ASP A 165
ILE A 166
ILE A  19
 None
 0.91A 4ndnD-3etnA:
undetectable		 4ndnD-3etnA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.12A 4ptjA-3etnA:
undetectable		 4ptjA-3etnA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.12A 4qleA-3etnA:
undetectable		 4qleA-3etnA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.08A 4qlgB-3etnA:
undetectable		 4qlgB-3etnA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 9 LEU A 130
GLY A  98
LEU A 106
VAL A 104
THR A 107
 None
 1.26A 4x3mB-3etnA:
undetectable		 4x3mB-3etnA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.12A 4x5fA-3etnA:
undetectable		 4x5fA-3etnA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5F_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.14A 4x5fB-3etnA:
undetectable		 4x5fB-3etnA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5H_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.13A 4x5hA-3etnA:
undetectable		 4x5hA-3etnA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.04A 5e8qA-3etnA:
undetectable		 5e8qA-3etnA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.11A 5e8qB-3etnA:
undetectable		 5e8qB-3etnA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.11A 5eajB-3etnA:
2.0		 5eajB-3etnA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		5 / 12 ILE A  54
LEU A 167
THR A 140
ILE A  19
THR A  45
 None
 1.12A 5ujxB-3etnA:
2.0		 5ujxB-3etnA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		4 / 7 THR A  45
LEU A  92
ILE A  32
PHE A  62
 None
 0.96A 5zsfA-3etnA:
undetectable
5zsfB-3etnA:
undetectable		 5zsfA-3etnA:
14.03
5zsfB-3etnA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 3etn PUTATIVE
PHOSPHOSUGAR
ISOMERASE INVOLVED
IN CAPSULE FORMATION
(Bacteroides
fragilis) 		4 / 7 ALA A  28
ASP A 165
ILE A 166
ILE A  19
 None
 0.89A 6fbnA-3etnA:
undetectable		 6fbnA-3etnA:
20.11