SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eto'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 3eto NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 1
(Homo
sapiens) 		5 / 11 ILE A1719
ASN A1485
LEU A1713
VAL A1605
LEU A1575
 None
 1.05A 3a51A-3etoA:
undetectable		 3a51A-3etoA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3eto NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 1
(Homo
sapiens) 		5 / 12 GLN A1493
GLY A1705
ALA A1706
SER A1709
LEU A1710
 None
 1.08A 3ln1B-3etoA:
undetectable		 3ln1B-3etoA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3eto NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 1
(Homo
sapiens) 		4 / 8 VAL A1605
LEU A1601
ILE A1719
VAL A1722
 None
 0.81A 5nujA-3etoA:
undetectable		 5nujA-3etoA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3eto NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 1
(Homo
sapiens) 		5 / 10 ILE A1715
VAL A1700
ALA A1697
LEU A1704
LEU A1601
 None
 1.04A 6f6nA-3etoA:
undetectable
6f6nB-3etoA:
undetectable		 6f6nA-3etoA:
14.23
6f6nB-3etoA:
14.77