SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3etv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 5 PHE A 191
TYR A 179
LEU A 135
VAL A  80
 None
 1.31A 1dz6A-3etvA:
undetectable		 1dz6A-3etvA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 296
ILE A 322
VAL A 300
ILE A 307
ILE A 306
 None
 0.93A 1epbB-3etvA:
undetectable		 1epbB-3etvA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 7 TYR A 168
MET A 172
ASP A 173
ASP A 169
 None
 0.96A 1t03A-3etvA:
undetectable		 1t03A-3etvA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DG9_A_RAPA501_1
(FK506-BINDING
PROTEIN 1A)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		5 / 11 TYR A 179
PHE A 191
VAL A 204
LEU A 208
ILE A 138
 None
 1.10A 2dg9A-3etvA:
undetectable		 2dg9A-3etvA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		5 / 11 THR A 263
ALA A 267
SER A 232
GLY A 233
SER A 259
 None
 1.15A 2f162-3etvA:
undetectable		 2f162-3etvA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		5 / 11 THR A 263
ALA A 267
SER A 232
GLY A 233
SER A 259
 None
 1.15A 2f16N-3etvA:
undetectable		 2f16N-3etvA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 110
TYR A 109
GLN A 112
 None
 0.63A 2wekA-3etvA:
undetectable		 2wekA-3etvA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF3_A_PAUA314_0
(PANTOTHENATE KINASE)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 6 TYR A 179
PHE A 174
MET A 172
PHE A 171
 None
 1.30A 3af3A-3etvA:
undetectable		 3af3A-3etvA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		5 / 12 THR A 263
ALA A 267
SER A 232
GLY A 233
SER A 259
 None
 1.07A 3mg02-3etvA:
undetectable
3mg0V-3etvA:
undetectable		 3mg02-3etvA:
19.72
3mg0V-3etvA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		5 / 11 THR A 263
ALA A 267
SER A 232
GLY A 233
SER A 259
 None
 1.10A 3mg0N-3etvA:
undetectable		 3mg0N-3etvA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 7 ILE A  10
LEU A  96
VAL A 132
SER A 133
 None
 0.91A 3r9vA-3etvA:
undetectable
3r9vB-3etvA:
3.1		 3r9vA-3etvA:
25.48
3r9vB-3etvA:
25.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 5 THR A 147
ILE A 146
LYS A 145
PHE A 271
 None
 1.48A 4ac9C-3etvA:
undetectable		 4ac9C-3etvA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 5 THR A 147
ILE A 146
LYS A 145
PHE A 271
 None
 1.47A 4acaC-3etvA:
undetectable		 4acaC-3etvA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTP_A_ASCA802_0
(RRNA N-GLYCOSIDASE)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		4 / 5 ILE A  77
ASN A 106
TYR A 109
ILE A 120
 None
 1.08A 4jtpA-3etvA:
undetectable		 4jtpA-3etvA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 206
LEU A 185
VAL A 132
TYR A  93
PHE A 191
 None
 1.33A 5vlmE-3etvA:
2.4		 5vlmE-3etvA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 129
GLN A 203
LYS A 137
 None
 0.86A 6exiB-3etvA:
undetectable		 6exiB-3etvA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 3etv PROTEIN TRANSPORT
PROTEIN TIP20,
PROTEIN TRANSPORT
PROTEIN DSL1 CHIMERA
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 129
GLN A 203
LYS A 137
 None
 0.90A 6exiA-3etvA:
undetectable		 6exiA-3etvA:
10.73