SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3euc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		5 / 10 LEU A  89
VAL A 256
GLU A 269
LEU A 268
VAL A 224
 None
 1.16A 1cqpA-3eucA:
undetectable
1cqpB-3eucA:
undetectable		 1cqpA-3eucA:
15.76
1cqpB-3eucA:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		3 / 3 LEU A  43
PRO A  44
LEU A  47
 None
 0.48A 1hrkA-3eucA:
undetectable		 1hrkA-3eucA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		5 / 9 GLY A 239
ILE A  96
VAL A 195
ILE A 159
VAL A 111
 None
 0.92A 2nnhB-3eucA:
undetectable		 2nnhB-3eucA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GCS_A_BAXA401_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		4 / 6 VAL A 111
LEU A 149
ILE A  97
ILE A 159
 None
 0.87A 3gcsA-3eucA:
undetectable		 3gcsA-3eucA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		5 / 12 ALA A 185
SER A 192
LEU A 244
LEU A 218
GLY A 216
 None
 1.11A 3k2hA-3eucA:
2.0		 3k2hA-3eucA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB513_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		5 / 12 ALA A 185
SER A 192
LEU A 244
LEU A 218
GLY A 216
 None
 1.12A 3k2hB-3eucA:
undetectable		 3k2hB-3eucA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		3 / 3 PRO A 165
SER A 303
ASN A 167
 None
None
SO4  A 368 (-3.4A)
 0.73A 3lslG-3eucA:
0.5		 3lslG-3eucA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		3 / 3 GLU A 269
LEU A 265
LEU A 229
 None
 0.76A 3ohtA-3eucA:
undetectable		 3ohtA-3eucA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		3 / 3 GLU A 269
LEU A 265
LEU A 229
 None
 0.78A 3ohtB-3eucA:
undetectable		 3ohtB-3eucA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		4 / 5 THR A 169
GLY A 117
PRO A 114
ASN A 166
 None
 1.17A 3u8qA-3eucA:
undetectable		 3u8qA-3eucA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		4 / 6 PHE A 173
GLY A 117
LEU A 137
VAL A 115
 None
 1.02A 4dubA-3eucA:
undetectable		 4dubA-3eucA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		4 / 5 MET A 148
LEU A 143
PRO A 157
SER A 192
 None
 1.47A 4kmmB-3eucA:
2.1		 4kmmB-3eucA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_2
(NUPC FAMILY PROTEIN)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		3 / 3 THR A 346
ASN A 171
PHE A 141
 None
 0.82A 4pd9A-3eucA:
undetectable		 4pd9A-3eucA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		4 / 7 LEU A 137
PRO A 114
ILE A 181
LEU A 149
 None
 1.06A 5fxtA-3eucA:
undetectable		 5fxtA-3eucA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA410_0
(UNCHARACTERIZED
PROTEIN KDOO)		 3euc HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE 2
(Cupriavidus
pinatubonensis) 		4 / 4 GLY A  90
LEU A  89
VAL A 256
GLU A 261
 None
 1.17A 5yw0A-3eucA:
undetectable		 5yw0A-3eucA:
25.13