SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3euf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 ARG A 138
THR A 141
GLU A 248
MET A 249
GLU A 250
 PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.33A 1jdvA-3eufA:
24.5
1jdvD-3eufA:
24.4		 1jdvA-3eufA:
23.37
1jdvD-3eufA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 ARG A 138
THR A 141
GLU A 248
MET A 249
GLU A 250
 PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.32A 1jdvB-3eufA:
24.6
1jdvC-3eufA:
25.1		 1jdvB-3eufA:
23.37
1jdvC-3eufA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 ARG A 138
THR A 141
GLU A 248
MET A 249
GLU A 250
 PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.33A 1jdvA-3eufA:
24.5
1jdvD-3eufA:
24.4		 1jdvA-3eufA:
23.37
1jdvD-3eufA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 12 ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.32A 1jdvE-3eufA:
24.5
1jdvF-3eufA:
2.1		 1jdvE-3eufA:
23.37
1jdvF-3eufA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.38A 1odiA-3eufA:
16.2		 1odiA-3eufA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.37A 1odiB-3eufA:
24.8		 1odiB-3eufA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.40A 1odiC-3eufA:
24.8		 1odiC-3eufA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.35A 1odiD-3eufA:
24.7		 1odiD-3eufA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.38A 1odiE-3eufA:
24.7		 1odiE-3eufA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.37A 1odiF-3eufA:
24.6		 1odiF-3eufA:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 9 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.30A 1pk7A-3eufA:
24.9		 1pk7A-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_B_ADNB1246_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.32A 1pk7B-3eufA:
25.3		 1pk7B-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 10 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.31A 1pk7C-3eufA:
25.4		 1pk7C-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 10 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.30A 1pk9A-3eufA:
25.0		 1pk9A-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 9 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.30A 1pk9B-3eufA:
25.2		 1pk9B-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.21A 1pk9C-3eufA:
24.3		 1pk9C-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 10 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.32A 1pw7A-3eufA:
25.1		 1pw7A-3eufA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 9 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.33A 1pw7B-3eufA:
25.2		 1pw7B-3eufA:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 ARG A 138
TYR A 214
ASP A 221
GLU A 248
 PO4  A 401 (-3.0A)
None
None
None
 1.11A 1rjdA-3eufA:
undetectable		 1rjdA-3eufA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 ARG A 138
TYR A 214
ASP A 221
GLU A 248
 PO4  A 401 (-3.0A)
None
None
None
 1.12A 1rjdB-3eufA:
undetectable		 1rjdB-3eufA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.27A 1rxcB-3eufA:
26.8		 1rxcB-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 7 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.40A 1rxcC-3eufA:
25.9		 1rxcC-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 7 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.28A 1rxcD-3eufA:
26.7		 1rxcD-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.31A 1rxcE-3eufA:
26.9		 1rxcE-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 7 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.26A 1rxcF-3eufA:
27.0		 1rxcF-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.27A 1rxcI-3eufA:
27.0		 1rxcI-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.32A 1rxcK-3eufA:
25.5		 1rxcK-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 7 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.22A 1rxcL-3eufA:
27.0		 1rxcL-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 11 LEU A 307
GLY A 101
PRO A 102
ILE A 303
VAL A  72
 None
 1.12A 1tmxA-3eufA:
undetectable		 1tmxA-3eufA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.39A 1vhwA-3eufA:
25.0
1vhwD-3eufA:
25.1		 1vhwA-3eufA:
26.27
1vhwD-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_B_ADNB252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 9 MET A 110
ARG A 138
GLY A 143
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.42A 1vhwB-3eufA:
24.9
1vhwF-3eufA:
24.6		 1vhwB-3eufA:
26.27
1vhwF-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.40A 1vhwC-3eufA:
25.1
1vhwE-3eufA:
24.9		 1vhwC-3eufA:
26.27
1vhwE-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.40A 1vhwA-3eufA:
25.0
1vhwD-3eufA:
25.1		 1vhwA-3eufA:
26.27
1vhwD-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.39A 1vhwC-3eufA:
25.1
1vhwE-3eufA:
24.9		 1vhwC-3eufA:
26.27
1vhwE-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 10 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.41A 1vhwB-3eufA:
24.9
1vhwF-3eufA:
24.6		 1vhwB-3eufA:
26.27
1vhwF-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		8 / 10 MET A 110
ARG A 138
THR A 141
GLY A 143
THR A 210
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.58A 1z35A-3eufA:
23.8		 1z35A-3eufA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 9 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.45A 1z37A-3eufA:
23.7		 1z37A-3eufA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.38A 2ac7A-3eufA:
23.4
2ac7B-3eufA:
23.4		 2ac7A-3eufA:
24.33
2ac7B-3eufA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.38A 2ac7A-3eufA:
23.4
2ac7B-3eufA:
23.4		 2ac7A-3eufA:
24.33
2ac7B-3eufA:
24.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.74A 3kvrA-3eufA:
46.5		 3kvrA-3eufA:
75.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVR_A_URFA2001_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		9 / 10 THR A 141
GLY A 143
PHE A 213
GLN A 217
ARG A 219
GLU A 248
MET A 249
LEU A 272
LEU A 273
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-4.4A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
None
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
 0.26A 3kvrA-3eufA:
46.5		 3kvrA-3eufA:
75.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.73A 3kvrB-3eufA:
46.7		 3kvrB-3eufA:
75.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KVR_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		9 / 10 THR A 141
GLY A 143
PHE A 213
GLN A 217
ARG A 219
GLU A 248
MET A 249
LEU A 272
LEU A 273
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-4.4A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
None
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
 0.28A 3kvrB-3eufA:
46.7		 3kvrB-3eufA:
75.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.23A 3kvvA-3eufA:
25.8		 3kvvA-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.24A 3kvvB-3eufA:
25.6		 3kvvB-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.24A 3kvvC-3eufA:
25.3		 3kvvC-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.31A 3kvvD-3eufA:
25.1		 3kvvD-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.27A 3kvvE-3eufA:
26.1		 3kvvE-3eufA:
27.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.28A 3kvvF-3eufA:
25.0		 3kvvF-3eufA:
27.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		8 / 9 THR A 141
GLY A 143
GLN A 217
ARG A 219
GLU A 248
MET A 249
LEU A 272
LEU A 273
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
None
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
 0.25A 3nbqA-3eufA:
48.9		 3nbqA-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_A_URFA400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 9 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.73A 3nbqA-3eufA:
48.9		 3nbqA-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
LEU A 272
LEU A 273
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
 0.23A 3nbqB-3eufA:
48.7		 3nbqB-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.76A 3nbqB-3eufA:
48.7		 3nbqB-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
LEU A 272
LEU A 273
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
 0.26A 3nbqC-3eufA:
48.5		 3nbqC-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.75A 3nbqC-3eufA:
48.5		 3nbqC-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		8 / 9 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
LEU A 272
LEU A 273
ARG A 275
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
None
 0.28A 3nbqD-3eufA:
48.5		 3nbqD-3eufA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NBQ_D_URFD400_1
(URIDINE
PHOSPHORYLASE 1)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 9 THR A 141
GLY A 143
LEU A 272
LEU A 273
ILE A 281
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 ( 4.2A)
BAU  A 400 ( 4.3A)
BAU  A 400 (-4.7A)
 0.84A 3nbqD-3eufA:
48.5		 3nbqD-3eufA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 9 ASP A 279
GLY A 278
ILE A 281
GLY A 144
ILE A 145
 None
None
BAU  A 400 (-4.7A)
None
None
 0.93A 3ogpA-3eufA:
undetectable		 3ogpA-3eufA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKA_A_SAMA400_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE H)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 12 GLY A 140
GLY A  60
ARG A 294
SER A 142
GLU A 290
 PO4  A 401 (-3.3A)
PO4  A 401 (-3.4A)
None
None
None
 0.94A 3tkaA-3eufA:
undetectable		 3tkaA-3eufA:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_A_ADNA251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 9 MET A 110
ARG A 138
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.43A 3u40A-3eufA:
23.9
3u40F-3eufA:
22.9		 3u40A-3eufA:
27.00
3u40F-3eufA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_B_ADNB251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 MET A 110
ARG A 138
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.41A 3u40B-3eufA:
23.9
3u40C-3eufA:
23.5		 3u40B-3eufA:
27.00
3u40C-3eufA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 12 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.30A 3u40B-3eufA:
23.9
3u40C-3eufA:
23.5		 3u40B-3eufA:
27.00
3u40C-3eufA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.30A 3u40D-3eufA:
24.0
3u40E-3eufA:
23.3		 3u40D-3eufA:
27.00
3u40E-3eufA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 12 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.34A 3u40D-3eufA:
24.1
3u40E-3eufA:
23.3		 3u40D-3eufA:
27.00
3u40E-3eufA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 MET A 110
ARG A 138
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.36A 3u40A-3eufA:
23.8
3u40F-3eufA:
22.9		 3u40A-3eufA:
27.00
3u40F-3eufA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 11 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.40A 3uawA-3eufA:
24.1		 3uawA-3eufA:
24.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		7 / 10 MET A 110
ARG A 138
THR A 141
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.38A 3uayA-3eufA:
24.6		 3uayA-3eufA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.34A 4d9hA-3eufA:
25.0		 4d9hA-3eufA:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 10 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.38A 4da7A-3eufA:
24.9		 4da7A-3eufA:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		6 / 11 MET A 110
ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.32A 4danA-3eufA:
24.5		 4danA-3eufA:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 12 ARG A 138
GLY A 143
GLU A 248
MET A 249
GLU A 250
 PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.42A 4danA-3eufA:
24.5
4danB-3eufA:
24.4		 4danA-3eufA:
27.05
4danB-3eufA:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.28A 4e1vA-3eufA:
25.8		 4e1vA-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 7 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.33A 4e1vB-3eufA:
25.5		 4e1vB-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.31A 4e1vC-3eufA:
25.3		 4e1vC-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.32A 4e1vD-3eufA:
25.5		 4e1vD-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.32A 4e1vE-3eufA:
26.0		 4e1vE-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 6 GLY A 143
GLN A 217
ARG A 219
MET A 249
 BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.30A 4e1vF-3eufA:
25.5		 4e1vF-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.50A 4e1vG-3eufA:
25.1		 4e1vG-3eufA:
26.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 8 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.31A 4e1vH-3eufA:
25.7		 4e1vH-3eufA:
26.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 7 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.25A 4txnA-3eufA:
41.4		 4txnA-3eufA:
40.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 7 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.26A 4txnB-3eufA:
41.6		 4txnB-3eufA:
40.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 7 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.25A 4txnC-3eufA:
41.6		 4txnC-3eufA:
40.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 7 THR A 141
GLY A 143
GLN A 217
ARG A 219
MET A 249
 PO4  A 401 ( 3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.1A)
BAU  A 400 (-3.0A)
BAU  A 400 (-3.8A)
 0.25A 4txnD-3eufA:
41.6		 4txnD-3eufA:
40.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 9 MET A 110
ARG A 138
GLY A 143
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
PO4  A 401 (-3.0A)
BAU  A 400 (-3.3A)
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.40A 5i3cA-3eufA:
24.8		 5i3cA-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 10 MET A 110
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.32A 5i3cB-3eufA:
25.1		 5i3cB-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		5 / 11 MET A 110
GLY A 143
GLU A 248
MET A 249
GLU A 250
 BAU  A 400 (-3.5A)
BAU  A 400 (-3.3A)
None
BAU  A 400 (-3.8A)
PO4  A 401 ( 4.2A)
 0.31A 5i3cC-3eufA:
24.9		 5i3cC-3eufA:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		3 / 3 VAL A 270
TYR A 291
GLN A 293
 None
 0.75A 5qgkA-3eufA:
undetectable		 5qgkA-3eufA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		3 / 3 VAL A 270
TYR A 291
GLN A 293
 None
 0.73A 5qgrA-3eufA:
undetectable		 5qgrA-3eufA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		3 / 3 VAL A 270
TYR A 291
GLN A 293
 None
 0.67A 5qgtA-3eufA:
undetectable		 5qgtA-3eufA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 5 THR A 141
THR A 210
GLN A 217
ASP A 160
 PO4  A 401 ( 3.0A)
None
BAU  A 400 (-3.1A)
None
 1.32A 6ectA-3eufA:
undetectable		 6ectA-3eufA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 5 THR A 271
THR A 210
GLN A 217
ASP A 160
 None
None
BAU  A 400 (-3.1A)
None
 1.45A 6ectA-3eufA:
undetectable		 6ectA-3eufA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 3euf URIDINE
PHOSPHORYLASE 1
(Homo
sapiens) 		4 / 5 THR A 271
THR A 210
GLN A 217
ASP A 160
 None
None
BAU  A 400 (-3.1A)
None
 1.43A 6ecxA-3eufA:
undetectable		 6ecxA-3eufA:
22.16