SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3euk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 3euk CHROMOSOME PARTITION
PROTEIN MUKF
([Haemophilus]
ducreyi) 		4 / 8 ASP E 404
LYS E 408
GLY E 410
ASP E 415
 None
 0.93A 2aouA-3eukE:
undetectable		 2aouA-3eukE:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 3euk CHROMOSOME PARTITION
PROTEIN MUKE
([Haemophilus]
ducreyi) 		3 / 3 PRO L 197
LEU L 103
ARG L 107
 None
 0.91A 3aqiA-3eukL:
undetectable		 3aqiA-3eukL:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 3euk CHROMOSOME PARTITION
PROTEIN MUKE
([Haemophilus]
ducreyi) 		5 / 12 LEU L 158
GLY L 155
TYR L 120
PHE L 114
LEU L  98
 None
 1.14A 5czyA-3eukL:
undetectable		 5czyA-3eukL:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 3euk CHROMOSOME PARTITION
PROTEIN MUKE
([Haemophilus]
ducreyi) 		5 / 12 VAL L  97
VAL L 154
GLY L 156
PHE L 178
GLU L 122
 None
 1.20A 6bqgA-3eukL:
undetectable		 6bqgA-3eukL:
15.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ESM_A_PZEA307_1
(MATRIX
METALLOPROTEINASE-9,
MATRIX
METALLOPROTEINASE-9)		 3euk CHROMOSOME PARTITION
PROTEIN MUKE
([Haemophilus]
ducreyi) 		3 / 3 TYR L  73
HIS L  34
PHE L  71
 None
 1.00A 6esmA-3eukL:
undetectable		 6esmA-3eukL:
16.03