SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_G_BEZG3385_0 (CES1 PROTEIN)	3eul	POSSIBLE NITRATE/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL (DNA-BINDING RESPONSE REGULATOR, LUXR FAMILY) (Mycobacterium tuberculosis)	3 / 3	SER A 31 VAL A 122 LEU A 123	None	0.72A	1yajG-3eulA: undetectable	1yajG-3eulA: 15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QO4_A_CHDA130_0 (LIVER-BASIC FATTY ACID BINDING PROTEIN)	3eul	POSSIBLE NITRATE/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL (DNA-BINDING RESPONSE REGULATOR, LUXR FAMILY) (Mycobacterium tuberculosis)	5 / 12	ILE A 96 ALA A 73 VAL A 85 MET A 64 ASP A 68	None	1.24A	2qo4A-3eulA: undetectable	2qo4A-3eulA: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KVR_A_URFA2001_1 (URIDINE PHOSPHORYLASE)	3eul	POSSIBLE NITRATE/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL (DNA-BINDING RESPONSE REGULATOR, LUXR FAMILY) (Mycobacterium tuberculosis)	5 / 10	GLY A 14 PHE A 20 GLU A 39 LEU A 59 ILE A 88	None	1.24A	3kvrA-3eulA: 2.9	3kvrA-3eulA: 20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KVR_B_URFB2011_1 (URIDINE PHOSPHORYLASE)	3eul	POSSIBLE NITRATE/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL (DNA-BINDING RESPONSE REGULATOR, LUXR FAMILY) (Mycobacterium tuberculosis)	5 / 10	GLY A 14 PHE A 20 GLU A 39 LEU A 59 ILE A 88	None	1.24A	3kvrB-3eulA: 3.0	3kvrB-3eulA: 20.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YAJ_G_BEZG3385_0","CES1 PROTEIN","3eul","POSSIBLE NITRATE\/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL (DNA-BINDING RESPONSE REGULATOR, LUXR FAMILY)","Mycobacterium tuberculosis",3,"SER A  31;VAL A 122;LEU A 123","None","0.72A","1yajG-3eulA:undetectable","1yajG-3eulA:15.53"],["2QO4_A_CHDA130_0","LIVER-BASIC FATTY ACID BINDING PROTEIN","3eul","POSSIBLE NITRATE\/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL (DNA-BINDING RESPONSE REGULATOR, LUXR FAMILY)","Mycobacterium tuberculosis",5,"ILE A  96;ALA A  73;VAL A  85;MET A  64;ASP A  68","None","1.24A","2qo4A-3eulA:undetectable","2qo4A-3eulA:21.05"],["3KVR_A_URFA2001_1","URIDINE PHOSPHORYLASE","3eul","POSSIBLE NITRATE\/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL (DNA-BINDING RESPONSE REGULATOR, LUXR FAMILY)","Mycobacterium tuberculosis",5,"GLY A  14;PHE A  20;GLU A  39;LEU A  59;ILE A  88","None","1.24A","3kvrA-3eulA:2.9","3kvrA-3eulA:20.33"],["3KVR_B_URFB2011_1","URIDINE PHOSPHORYLASE","3eul","POSSIBLE NITRATE\/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL (DNA-BINDING RESPONSE REGULATOR, LUXR FAMILY)","Mycobacterium tuberculosis",5,"GLY A  14;PHE A  20;GLU A  39;LEU A  59;ILE A  88","None","1.24A","3kvrB-3eulA:3.0","3kvrB-3eulA:20.33"]]