SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eup'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 3eup TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Cytophaga
hutchinsonii) 		4 / 7 ARG A   9
PHE A  13
ILE A  14
ASN A  49
 None
 1.15A 2zseA-3eupA:
undetectable		 2zseA-3eupA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 3eup TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Cytophaga
hutchinsonii) 		4 / 6 ALA A  57
ALA A  19
PRO A  20
THR A  18
 None
 1.04A 4dtzB-3eupA:
undetectable		 4dtzB-3eupA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3eup TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Cytophaga
hutchinsonii) 		3 / 3 VAL A  88
GLN A  77
CYH A  79
 None
 0.83A 5icxA-3eupA:
undetectable
5icxE-3eupA:
undetectable		 5icxA-3eupA:
18.64
5icxE-3eupA:
4.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3eup TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Cytophaga
hutchinsonii) 		3 / 3 VAL A  88
GLN A  77
CYH A  79
 None
 0.91A 5icxC-3eupA:
undetectable
5icxF-3eupA:
undetectable		 5icxC-3eupA:
18.64
5icxF-3eupA:
4.41