SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3evc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
ARG A 163
LYS A 182
 SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
None
None
 1.22A 1eizA-3evcA:
15.1		 1eizA-3evcA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
LEU A 105
LYS A 182
 SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.0A)
None
 0.66A 1eizA-3evcA:
15.1		 1eizA-3evcA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
LEU A 105
 SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.0A)
 0.31A 1ej0A-3evcA:
15.0		 1ej0A-3evcA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		4 / 5 THR A 161
LEU A 165
VAL A 168
LEU A 172
 None
 0.67A 1fbmE-3evcA:
undetectable		 1fbmE-3evcA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X1A_A_SAMA4264_0
(CRTF-RELATED PROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  83
LEU A 105
ASP A 131
ILE A 132
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.98A 1x1aA-3evcA:
8.9		 1x1aA-3evcA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  85
TRP A  87
LEU A 105
LYS A 182
 SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.0A)
None
 0.71A 2nyuA-3evcA:
14.4		 2nyuA-3evcA:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  85
TRP A  87
LEU A 105
LYS A 182
 SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.0A)
None
 0.65A 2nyuB-3evcA:
14.4		 2nyuB-3evcA:
20.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
ILE A 132
HIS A 133
ASP A 146
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.8A)
SAH  A 901 (-4.2A)
SAH  A 901 (-3.8A)
 0.35A 2oxtA-3evcA:
39.8		 2oxtA-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  58
GLY A  83
GLY A  86
TRP A  87
GLU A 111
ASP A 146
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.8A)
 0.81A 2oxtA-3evcA:
39.8		 2oxtA-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.33A 2oxtA-3evcA:
39.8		 2oxtA-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		3 / 3 SER A  56
HIS A 110
ASP A 131
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
 0.52A 2oxtA-3evcA:
39.8		 2oxtA-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  85
TRP A  87
THR A 104
LEU A 105
ILE A 132
HIS A 133
LYS A 182
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.8A)
SAH  A 901 (-4.2A)
None
 0.64A 2oxtB-3evcA:
39.8		 2oxtB-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		7 / 12 GLY A  58
GLY A  83
GLY A  85
TRP A  87
THR A 104
GLU A 111
LYS A 182
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.3A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
None
 0.93A 2oxtB-3evcA:
39.8		 2oxtB-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  83
GLY A  85
THR A 104
LEU A 105
ILE A 147
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 ( 4.2A)
 1.39A 2oxtB-3evcA:
39.8		 2oxtB-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 5 SER A  56
GLY A  86
HIS A 110
ASP A 131
ASP A 146
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.37A 2oxtB-3evcA:
39.8		 2oxtB-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_C_SAMC300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
ILE A 132
HIS A 133
ASP A 146
LYS A 182
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.8A)
SAH  A 901 (-4.2A)
SAH  A 901 (-3.8A)
None
 0.47A 2oxtC-3evcA:
39.6		 2oxtC-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		4 / 4 SER A  56
GLY A  58
HIS A 110
ASP A 131
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
 0.45A 2oxtC-3evcA:
39.6		 2oxtC-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 ASP A  79
GLY A  81
GLY A  85
HIS A 110
HIS A 133
ASP A 146
 SAH  A 901 ( 4.9A)
SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.8A)
SAH  A 901 (-4.2A)
SAH  A 901 (-3.8A)
 1.06A 2oxtD-3evcA:
39.8		 2oxtD-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
ASP A  79
GLY A  81
GLY A  83
GLY A  86
THR A 104
LEU A 105
HIS A 110
HIS A 133
ASP A 146
 SAH  A 901 (-3.2A)
SAH  A 901 ( 4.9A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.8A)
SAH  A 901 (-4.2A)
SAH  A 901 (-3.8A)
 0.34A 2oxtD-3evcA:
39.8		 2oxtD-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_D_SAMD300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.40A 2oxtD-3evcA:
39.8		 2oxtD-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OXT_D_SAMD300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		4 / 4 SER A  56
TRP A  87
ASP A 131
ILE A 132
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.39A 2oxtD-3evcA:
39.8		 2oxtD-3evcA:
48.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.29A 2pxcA-3evcA:
41.9		 2pxcA-3evcA:
54.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PXC_A_SAMA500_0
(GENOME POLYPROTEIN
[CONTAINS: CAPSID
PROTEIN C (CORE
PROTEIN)
ENVELOPE PROTEIN M
(MATRIX PROTEIN)
MAJOR ENVELOPE
PROTEIN E
NON-STRUCTURAL
PROTEIN 1 (NS1)
NON-STRUCTURAL
PROTEIN 2A (NS2A)
FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT
FLAVIVIRIN PROTEASE
NS3 CATALYTIC
SUBUNIT
NON-STRUCTURAL
PROTEIN 4A (NS4A)
NON-STRUCTURAL
PROTEIN 4B (NS4B)
RNA-DIRECTED RNA
POLYMERASE (EC
2.7.7.48) (NS5)])		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.24A 2pxcA-3evcA:
41.9		 2pxcA-3evcA:
54.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_A_SAMA1248_0
(NON-STRUCTURAL
PROTEIN 5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
LEU A 105
ASP A 131
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.7A)
SAH  A 901 ( 4.2A)
 0.24A 2wa2A-3evcA:
33.8		 2wa2A-3evcA:
52.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
LEU A 105
ASP A 146
ILE A 147
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.20A 2wa2B-3evcA:
41.1		 2wa2B-3evcA:
52.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WA2_B_SAMB1267_0
(NON-STRUCTURAL
PROTEIN 5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 SER A  56
GLY A  58
TRP A  87
THR A 167
ASP A 146
ILE A 147
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.6A)
None
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 1.30A 2wa2B-3evcA:
41.1		 2wa2B-3evcA:
52.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  85
GLY A  86
TRP A  87
LEU A 105
 SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.0A)
 0.35A 3douA-3evcA:
14.5		 3douA-3evcA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.28A 3eluA-3evcA:
40.9		 3eluA-3evcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.25A 3eluA-3evcA:
40.9		 3eluA-3evcA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.24A 3elwA-3evcA:
42.8		 3elwA-3evcA:
61.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.27A 3elwA-3evcA:
42.8		 3elwA-3evcA:
61.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.34A 3embA-3evcA:
41.4		 3embA-3evcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
LEU A 105
GLU A 111
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.45A 3embA-3evcA:
41.4		 3embA-3evcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
 1.03A 3embA-3evcA:
41.4		 3embA-3evcA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.26A 3gczA-3evcA:
41.8		 3gczA-3evcA:
54.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GCZ_A_SAMA4633_0
(POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		11 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
LEU A 105
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.21A 3gczA-3evcA:
41.8		 3gczA-3evcA:
54.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  83
GLY A  85
ASP A 131
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.63A 3ihtA-3evcA:
7.1		 3ihtA-3evcA:
22.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.34A 3p97A-3evcA:
40.7		 3p97A-3evcA:
54.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 3p97A-3evcA:
40.7		 3p97A-3evcA:
54.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_A_SAMA263_0
(NON-STRUCTURAL
PROTEIN 5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  86
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 1.42A 3p97A-3evcA:
40.7		 3p97A-3evcA:
54.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.22A 3p97C-3evcA:
40.7		 3p97C-3evcA:
54.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.32A 3p97C-3evcA:
40.7		 3p97C-3evcA:
54.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B17_A_SAMA1358_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE M)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		7 / 12 SER A  56
GLY A  81
GLY A  85
GLY A  86
TRP A  87
ASP A 131
ASP A 146
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.67A 4b17A-3evcA:
13.4		 4b17A-3evcA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_B_SAMB1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 ASP A  79
GLY A  83
GLY A  86
HIS A 110
ASP A 146
 SAH  A 901 ( 4.9A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.8A)
 1.17A 4blvB-3evcA:
6.8		 4blvB-3evcA:
22.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.28A 4ctjA-3evcA:
40.8		 4ctjA-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 4ctjA-3evcA:
40.8		 4ctjA-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.31A 4ctjC-3evcA:
40.6		 4ctjC-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 4ctjC-3evcA:
40.6		 4ctjC-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.30A 4ctkA-3evcA:
40.7		 4ctkA-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_A_SAMA1263_0
(POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 4ctkA-3evcA:
40.7		 4ctkA-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 4ctkC-3evcA:
40.7		 4ctkC-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 146
ILE A 147
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.17A 4ctkC-3evcA:
40.7		 4ctkC-3evcA:
51.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  83
GLY A  85
THR A 104
LEU A 105
ILE A 132
 SAH  A 901 (-3.3A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.8A)
 0.63A 4n48A-3evcA:
16.4		 4n48A-3evcA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  83
GLY A  85
THR A 104
LEU A 105
ILE A 132
 SAH  A 901 (-3.3A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.8A)
 0.60A 4n48B-3evcA:
16.8		 4n48B-3evcA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  83
GLY A  85
THR A 104
LEU A 105
ILE A 132
 SAH  A 901 (-3.3A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-4.5A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.8A)
 0.63A 4n49A-3evcA:
15.3		 4n49A-3evcA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGH_B_SAMB401_0
(CAFFEIC ACID
O-METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 SER A  56
ASP A  79
GLY A  81
LEU A 105
ASP A 131
 SAH  A 901 (-2.6A)
SAH  A 901 ( 4.9A)
SAH  A 901 (-3.4A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.7A)
 1.17A 4pghB-3evcA:
8.0		 4pghB-3evcA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  83
GLY A  85
LEU A 105
LYS A 182
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-4.0A)
None
 0.87A 4uciA-3evcA:
9.0		 4uciA-3evcA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  83
GLY A  85
LEU A 105
LYS A 182
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-4.0A)
None
 0.86A 4uciB-3evcA:
7.9		 4uciB-3evcA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		3 / 3 SER A  56
ASP A 131
ASP A 146
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.78A 4uckA-3evcA:
9.3		 4uckA-3evcA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_1
(RNA-DIRECTED RNA
POLYMERASE L)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		4 / 6 SER A  56
GLY A  81
ASP A 131
ASP A 146
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.74A 4uckB-3evcA:
9.7		 4uckB-3evcA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		4 / 7 PHE A 126
GLY A  86
THR A  59
LEU A 259
 None
SAH  A 901 (-3.1A)
None
None
 0.92A 4zdzA-3evcA:
undetectable		 4zdzA-3evcA:
20.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.32A 5e9qA-3evcA:
40.4		 5e9qA-3evcA:
53.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 5e9qA-3evcA:
40.4		 5e9qA-3evcA:
53.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.32A 5e9qC-3evcA:
40.6		 5e9qC-3evcA:
53.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.32A 5e9qC-3evcA:
40.6		 5e9qC-3evcA:
53.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 5ec8A-3evcA:
40.5		 5ec8A-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  85
GLU A 111
ASP A 146
ILE A 147
 SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.88A 5ec8A-3evcA:
40.5		 5ec8A-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_A_SAMA301_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 146
ILE A 147
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.31A 5ec8A-3evcA:
40.5		 5ec8A-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.22A 5ec8C-3evcA:
40.2		 5ec8C-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 5ec8C-3evcA:
40.2		 5ec8C-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.44A 5ehgA-3evcA:
40.5		 5ehgA-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 5ehgA-3evcA:
40.5		 5ehgA-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.33A 5ehgC-3evcA:
40.5		 5ehgC-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.32A 5ehgC-3evcA:
40.5		 5ehgC-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  85
GLU A 111
ASP A 146
ILE A 147
 SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.94A 5ehgC-3evcA:
40.5		 5ehgC-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.28A 5ehiA-3evcA:
40.8		 5ehiA-3evcA:
51.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.19A 5ehiC-3evcA:
40.8		 5ehiC-3evcA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.32A 5eifA-3evcA:
40.8		 5eifA-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 5eifA-3evcA:
40.8		 5eifA-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.26A 5eifC-3evcA:
40.6		 5eifC-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 5eifC-3evcA:
40.6		 5eifC-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.30A 5eiwA-3evcA:
40.6		 5eiwA-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.31A 5eiwC-3evcA:
40.6		 5eiwC-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.32A 5eiwC-3evcA:
40.6		 5eiwC-3evcA:
51.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 SER A  56
GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-2.6A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.30A 5ekxA-3evcA:
40.9		 5ekxA-3evcA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.24A 5ekxB-3evcA:
40.9		 5ekxB-3evcA:
51.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 5ekxB-3evcA:
40.9		 5ekxB-3evcA:
51.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		4 / 8 PHE A 126
GLY A  86
THR A  59
LEU A 259
 None
SAH  A 901 (-3.1A)
None
None
 0.93A 5esfA-3evcA:
undetectable		 5esfA-3evcA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESJ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		4 / 8 PHE A 126
GLY A  86
THR A  59
LEU A 259
 None
SAH  A 901 (-3.1A)
None
None
 0.92A 5esjA-3evcA:
undetectable		 5esjA-3evcA:
21.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.28A 5ikmA-3evcA:
40.7		 5ikmA-3evcA:
54.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.28A 5ikmA-3evcA:
40.7		 5ikmA-3evcA:
54.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 ( 4.2A)
 0.29A 5kqrA-3evcA:
42.2		 5kqrA-3evcA:
54.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.34A 5kqsA-3evcA:
41.9		 5kqsA-3evcA:
54.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.29A 5kqsA-3evcA:
41.9		 5kqsA-3evcA:
54.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 ( 4.2A)
 0.39A 5m5bA-3evcA:
42.3		 5m5bA-3evcA:
54.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_A_SAMA301_0
(NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.22A 5njvA-3evcA:
41.4		 5njvA-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_A_SAMA301_0
(NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.30A 5njvA-3evcA:
41.4		 5njvA-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.23A 5njvB-3evcA:
41.5		 5njvB-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.31A 5njvB-3evcA:
41.5		 5njvB-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_B_SAMB301_0
(NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  86
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 1.35A 5njvB-3evcA:
41.5		 5njvB-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.41A 5njvC-3evcA:
40.4		 5njvC-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.33A 5njvC-3evcA:
40.4		 5njvC-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_C_SAMC301_0
(NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  85
GLU A 111
ASP A 146
ILE A 147
 SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.93A 5njvC-3evcA:
40.4		 5njvC-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NJV_D_SAMD301_0
(NS5)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.28A 5njvD-3evcA:
40.5		 5njvD-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
HIS A 110
GLU A 111
ILE A 147
LYS A 182
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 ( 4.2A)
None
 0.40A 5vimA-3evcA:
41.5		 5vimA-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_A_SAMA301_1
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		4 / 4 SER A  56
THR A 104
ASP A 131
ASP A 146
 SAH  A 901 (-2.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.24A 5vimA-3evcA:
41.5		 5vimA-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
HIS A 110
GLU A 111
ILE A 147
LYS A 182
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 ( 4.2A)
None
 0.32A 5vimB-3evcA:
41.7		 5vimB-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  85
HIS A 110
GLU A 111
ILE A 147
LYS A 182
 SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 ( 4.2A)
None
 0.96A 5vimB-3evcA:
41.7		 5vimB-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5VIM_B_SAMB301_1
(METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		4 / 4 SER A  56
THR A 104
ASP A 131
ASP A 146
 SAH  A 901 (-2.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.22A 5vimB-3evcA:
41.7		 5vimB-3evcA:
53.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
ASP A 146
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.68A 5wz1A-3evcA:
41.5		 5wz1A-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.33A 5wz1A-3evcA:
41.5		 5wz1A-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  86
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 1.44A 5wz1A-3evcA:
41.5		 5wz1A-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		8 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
GLU A 111
ASP A 131
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
 0.69A 5wz1B-3evcA:
41.4		 5wz1B-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 ( 4.2A)
 0.31A 5wz1B-3evcA:
41.4		 5wz1B-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.33A 5wz1C-3evcA:
41.3		 5wz1C-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
ASP A 146
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.73A 5wz1C-3evcA:
41.3		 5wz1C-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  86
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 1.44A 5wz1C-3evcA:
41.3		 5wz1C-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.35A 5wz1D-3evcA:
41.4		 5wz1D-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
ASP A 146
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.73A 5wz1D-3evcA:
41.4		 5wz1D-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  86
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 1.42A 5wz1D-3evcA:
41.4		 5wz1D-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.32A 5wz1E-3evcA:
41.3		 5wz1E-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		7 / 12 GLY A  58
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
 0.83A 5wz1E-3evcA:
41.3		 5wz1E-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  86
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 1.46A 5wz1E-3evcA:
41.3		 5wz1E-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.33A 5wz1F-3evcA:
41.5		 5wz1F-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
ASP A 146
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.72A 5wz1F-3evcA:
41.5		 5wz1F-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  86
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 1.43A 5wz1F-3evcA:
41.5		 5wz1F-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.34A 5wz1G-3evcA:
41.3		 5wz1G-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
ASP A 146
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.74A 5wz1G-3evcA:
41.3		 5wz1G-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  86
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 1.40A 5wz1G-3evcA:
41.3		 5wz1G-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.34A 5wz1H-3evcA:
41.3		 5wz1H-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		7 / 12 GLY A  58
GLY A  86
TRP A  87
THR A 104
HIS A 110
GLU A 111
ASP A 131
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.7A)
 0.82A 5wz1H-3evcA:
41.3		 5wz1H-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  85
TRP A  87
ASP A 146
ILE A 147
 SAH  A 901 (-3.4A)
SAH  A 901 ( 4.4A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.98A 5wz1H-3evcA:
41.3		 5wz1H-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  86
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 1.39A 5wz1H-3evcA:
41.3		 5wz1H-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.27A 5wz2A-3evcA:
41.4		 5wz2A-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.26A 5wz2A-3evcA:
41.4		 5wz2A-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		10 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.28A 5wz2B-3evcA:
41.5		 5wz2B-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.26A 5wz2B-3evcA:
41.5		 5wz2B-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_B_SAMB601_0
(NS5 MTASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  86
TRP A  87
HIS A 110
ASP A 131
ASP A 146
ILE A 147
 SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 1.43A 5wz2B-3evcA:
41.5		 5wz2B-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		9 / 12 GLY A  58
GLY A  81
GLY A  83
GLY A  86
TRP A  87
THR A 104
HIS A 110
ASP A 146
ILE A 147
 SAH  A 901 (-3.2A)
SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.8A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.30A 5wz2C-3evcA:
41.4		 5wz2C-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		6 / 12 GLY A  81
GLY A  58
GLY A  86
GLY A  83
THR A  59
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.2A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.3A)
None
SAH  A 901 (-3.8A)
 1.27A 5wz2C-3evcA:
41.4		 5wz2C-3evcA:
52.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		7 / 12 GLY A  81
GLY A  83
TRP A  87
THR A 104
GLU A 111
ASP A 146
ILE A 147
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.3A)
SAH  A 901 (-3.6A)
SAH  A 901 (-4.5A)
SAH  A 901 (-3.1A)
SAH  A 901 (-3.8A)
SAH  A 901 ( 4.2A)
 0.70A 5wz2C-3evcA:
41.4		 5wz2C-3evcA:
52.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  86
LEU A 105
ASP A 131
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.91A 5yn6A-3evcA:
10.6		 5yn6A-3evcA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  86
LEU A 105
ASP A 131
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.91A 5yniA-3evcA:
10.1		 5yniA-3evcA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		5 / 12 GLY A  81
GLY A  86
LEU A 105
ASP A 131
ASP A 146
 SAH  A 901 (-3.4A)
SAH  A 901 (-3.1A)
SAH  A 901 (-4.0A)
SAH  A 901 (-3.7A)
SAH  A 901 (-3.8A)
 0.86A 5ynmA-3evcA:
10.9		 5ynmA-3evcA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		4 / 8 THR A 236
SER A 212
PHE A  65
TYR A  70
 None
 1.16A 6eqpA-3evcA:
undetectable		 6eqpA-3evcA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J20_A_GBQA1201_1
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 3evc RNA-DIRECTED RNA
POLYMERASE NS5
(Yellow
fever
virus) 		4 / 7 TRP A  64
GLU A  67
HIS A  66
VAL A  71
 None
 1.06A 6j20A-3evcA:
undetectable		 6j20A-3evcA:
17.63