SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3evi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XZ5_B_ACHB1210_0 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3evi	PHOSDUCIN-LIKE PROTEIN 2 (Homo sapiens)	4 / 7	TYR A 167 VAL A 101 CYH A 152 ILE A 95	None	1.30A	2xz5B-3eviA: undetectable 2xz5E-3eviA: undetectable	2xz5B-3eviA: 18.43 2xz5E-3eviA: 18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XZ5_E_ACHE1210_0 (SOLUBLE ACETYLCHOLINE RECEPTOR)	3evi	PHOSDUCIN-LIKE PROTEIN 2 (Homo sapiens)	4 / 7	ILE A 95 TYR A 167 VAL A 101 CYH A 152	None	1.32A	2xz5D-3eviA: undetectable 2xz5E-3eviA: undetectable	2xz5D-3eviA: 18.43 2xz5E-3eviA: 18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTG_E_LFXE101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCAC GTAA)	3evi	PHOSDUCIN-LIKE PROTEIN 2 (Homo sapiens)	4 / 6	ALA A 201 ARG A 137 GLY A 90 GLU A 91	None	0.95A	5btgA-3eviA: undetectable 5btgB-3eviA: undetectable 5btgC-3eviA: undetectable	5btgA-3eviA: 14.25 5btgB-3eviA: 16.94 5btgC-3eviA: 14.25

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2XZ5_B_ACHB1210_0","SOLUBLE ACETYLCHOLINE RECEPTOR","3evi","PHOSDUCIN-LIKE PROTEIN 2","Homo sapiens",4,"TYR A 167;VAL A 101;CYH A 152;ILE A  95","None","1.30A","2xz5B-3eviA:undetectable;2xz5E-3eviA:undetectable","2xz5B-3eviA:18.43;2xz5E-3eviA:18.43"],["2XZ5_E_ACHE1210_0","SOLUBLE ACETYLCHOLINE RECEPTOR","3evi","PHOSDUCIN-LIKE PROTEIN 2","Homo sapiens",4,"ILE A  95;TYR A 167;VAL A 101;CYH A 152","None","1.32A","2xz5D-3eviA:undetectable;2xz5E-3eviA:undetectable","2xz5D-3eviA:18.43;2xz5E-3eviA:18.43"],["5BTG_E_LFXE101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA GYRASE SUBUNIT A;DNA SUBSTRATE 24-MER GGTCATGAATGACTATGCACGTAA","3evi","PHOSDUCIN-LIKE PROTEIN 2","Homo sapiens",4,"ALA A 201;ARG A 137;GLY A  90;GLU A  91","None","0.95A","5btgA-3eviA:undetectable;5btgB-3eviA:undetectable;5btgC-3eviA:undetectable","5btgA-3eviA:14.25;5btgB-3eviA:16.94;5btgC-3eviA:14.25"]]