SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3evk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C1F_A_X8ZA300_1
(BETA-LACTAMASE IMP-1)		 3evk SUPEROXIDE DISMUTASE
[FE]
(Pyrobaculum
aerophilum) 		5 / 11 VAL A 136
HIS A  90
HIS A 161
ASP A 176
GLU A 179
 None
MN  A 301 (-3.5A)
None
MN  A 301 (-2.6A)
None
 1.34A 4c1fA-3evkA:
undetectable
4c1fB-3evkA:
undetectable		 4c1fA-3evkA:
22.18
4c1fB-3evkA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3evk SUPEROXIDE DISMUTASE
[FE]
(Pyrobaculum
aerophilum) 		4 / 8 ILE A  92
PRO A 107
VAL A 201
TRP A 203
 None
 1.28A 4f4dB-3evkA:
undetectable		 4f4dB-3evkA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 3evk SUPEROXIDE DISMUTASE
[FE]
(Pyrobaculum
aerophilum) 		3 / 3 ASP A 195
GLY A 191
ASP A 189
 None
 0.64A 4xdtA-3evkA:
undetectable		 4xdtA-3evkA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 3evk SUPEROXIDE DISMUTASE
[FE]
(Pyrobaculum
aerophilum) 		5 / 12 ASP A  79
HIS A  83
HIS A  42
HIS A 180
ASP A 176
 None
None
MN  A 301 (-3.4A)
MN  A 301 (-3.5A)
MN  A 301 (-2.6A)
 1.44A 5ef8A-3evkA:
undetectable		 5ef8A-3evkA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3evk SUPEROXIDE DISMUTASE
[FE]
(Pyrobaculum
aerophilum) 		3 / 3 SER A  91
LEU A  30
MET A  97
 None
 0.76A 5ikrB-3evkA:
undetectable		 5ikrB-3evkA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 3evk SUPEROXIDE DISMUTASE
[FE]
(Pyrobaculum
aerophilum) 		5 / 12 LEU A 156
ASP A 176
ILE A  88
VAL A 145
ILE A 143
 None
MN  A 301 (-2.6A)
None
None
None
 0.91A 6dgxA-3evkA:
undetectable		 6dgxA-3evkA:
16.51