SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3evn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 7 PHE A 111
LEU A  88
ALA A  87
VAL A  73
 None
 0.90A 1epbA-3evnA:
undetectable		 1epbA-3evnA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 6 THR A 164
PHE A 178
GLU A 168
GLY A 173
 None
 0.95A 1icuA-3evnA:
undetectable
1icuB-3evnA:
undetectable		 1icuA-3evnA:
21.02
1icuB-3evnA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 6 PHE A 178
GLU A 168
GLY A 173
THR A 164
 None
 0.92A 1icuA-3evnA:
undetectable
1icuB-3evnA:
undetectable		 1icuA-3evnA:
21.02
1icuB-3evnA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 6 THR A 164
PHE A 178
GLU A 168
GLY A 173
 None
 0.93A 1icuC-3evnA:
undetectable
1icuD-3evnA:
undetectable		 1icuC-3evnA:
21.02
1icuD-3evnA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 7 SER A 185
GLU A 123
GLU A 282
GLU A  97
 None
 1.20A 1knyA-3evnA:
undetectable
1knyB-3evnA:
undetectable		 1knyA-3evnA:
20.53
1knyB-3evnA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 8 GLU A  97
SER A 185
GLU A 123
GLU A 282
 None
 1.14A 1knyA-3evnA:
undetectable
1knyB-3evnA:
undetectable		 1knyA-3evnA:
20.53
1knyB-3evnA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 6 THR A 164
PHE A 178
GLU A 168
GLY A 173
 None
 0.94A 1kqbA-3evnA:
undetectable
1kqbB-3evnA:
undetectable		 1kqbA-3evnA:
19.27
1kqbB-3evnA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 6 THR A 164
PHE A 178
GLU A 168
GLY A 173
 None
 0.93A 1kqbC-3evnA:
undetectable
1kqbD-3evnA:
undetectable		 1kqbC-3evnA:
19.27
1kqbD-3evnA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 6 PHE A 178
GLU A 168
GLY A 173
THR A 164
 None
 0.96A 1kqbC-3evnA:
undetectable
1kqbD-3evnA:
undetectable		 1kqbC-3evnA:
19.27
1kqbD-3evnA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 6 TYR A 316
SER A 213
ALA A 202
THR A 175
 None
 1.18A 1yvpB-3evnA:
undetectable		 1yvpB-3evnA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		5 / 9 LEU A 248
ILE A 151
LEU A 190
ILE A 136
TYR A 186
 None
 1.28A 2f7aA-3evnA:
1.1		 2f7aA-3evnA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		5 / 12 LEU A 140
VAL A 223
GLY A 222
ILE A 195
LEU A 190
 None
 1.06A 3ijdA-3evnA:
undetectable		 3ijdA-3evnA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 6 PHE A 100
PHE A 111
THR A 101
VAL A 309
 None
 1.23A 3lb3A-3evnA:
undetectable		 3lb3A-3evnA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 6 PHE A 100
PHE A 111
THR A 101
VAL A 309
 None
 1.21A 3lb3B-3evnA:
undetectable		 3lb3B-3evnA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		3 / 3 TYR A 182
TYR A 157
GLU A  97
 None
 0.74A 3pfgA-3evnA:
4.6		 3pfgA-3evnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 6 ASP A  69
LYS A  92
HIS A  93
ILE A 290
 None
 0.82A 5a06A-3evnA:
33.4		 5a06A-3evnA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 5 ASP A  69
LYS A  92
HIS A  93
ILE A 290
 None
 0.83A 5a06B-3evnA:
33.4		 5a06B-3evnA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 5 ASP A  69
LYS A  92
HIS A  93
ILE A 290
 None
 0.82A 5a06D-3evnA:
33.3		 5a06D-3evnA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 5 ASP A  69
LYS A  92
HIS A  93
ILE A 290
 None
 0.82A 5a06F-3evnA:
33.5		 5a06F-3evnA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		4 / 5 SER A 213
ARG A 317
GLY A 320
GLU A 322
 None
 1.15A 5btiA-3evnA:
undetectable
5btiB-3evnA:
2.9		 5btiA-3evnA:
22.47
5btiB-3evnA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECE_C_DVAC3010_0
(VLM2
DODECADEPSIPEPTIDE)		 3evn OXIDOREDUCTASE,
GFO/IDH/MOCA FAMILY
(Streptococcus
agalactiae) 		3 / 3 ALA A 156
PHE A 228
GLN A 212
 None
 0.75A 6eceA-3evnA:
undetectable		 6eceA-3evnA:
22.48