SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3evp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 10 HIS A  94
LEU A 211
LEU A 222
THR A 220
THR A 221
 None
None
CRO  A 224 ( 4.2A)
CRO  A 224 ( 4.5A)
None
 1.39A 1rj6A-3evpA:
undetectable		 1rj6A-3evpA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 10 HIS A  94
LEU A 211
LEU A 222
THR A 220
THR A 221
 None
None
CRO  A 224 ( 4.2A)
CRO  A 224 ( 4.5A)
None
 1.38A 1rj6B-3evpA:
undetectable		 1rj6B-3evpA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		4 / 7 ALA A 268
TYR A 250
ILE A 251
ILE A 101
 None
 0.90A 1upfB-3evpA:
undetectable		 1upfB-3evpA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		3 / 3 ASN A  83
LEU A 299
HIS A  82
 None
 0.83A 2q6fB-3evpA:
undetectable		 2q6fB-3evpA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		4 / 6 ILE A 101
PHE A 241
ALA A 245
ASN A  98
 None
 1.15A 3pgyA-3evpA:
undetectable
3pgyB-3evpA:
undetectable		 3pgyA-3evpA:
20.85
3pgyB-3evpA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A 229
VAL A 270
ASN A 279
ILE A 172
PHE A 166
 None
CRO  A 224 ( 4.9A)
CRO  A 224 ( 3.6A)
None
None
 1.21A 3t3rB-3evpA:
undetectable		 3t3rB-3evpA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A 229
VAL A 270
ASN A 279
ILE A 172
PHE A 166
 None
CRO  A 224 ( 4.9A)
CRO  A 224 ( 3.6A)
None
None
 1.25A 3t3rC-3evpA:
undetectable		 3t3rC-3evpA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 10 PHE A 229
VAL A 270
ASN A 279
ILE A 172
PHE A 166
 None
CRO  A 224 ( 4.9A)
CRO  A 224 ( 3.6A)
None
None
 1.19A 3t3rD-3evpA:
undetectable		 3t3rD-3evpA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		4 / 7 ASP A 177
THR A 266
SER A 186
PHE A 185
 None
 1.03A 4ac9C-3evpA:
undetectable		 4ac9C-3evpA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		4 / 6 VAL A 213
LEU A 211
LEU A 283
PHE A  78
 None
None
None
CRO  A 224 ( 4.4A)
 0.95A 4o1zA-3evpA:
undetectable		 4o1zA-3evpA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		6 / 12 ALA A 268
LEU A 222
ILE A 172
LEU A 200
TYR A 250
THR A 266
 None
CRO  A 224 ( 4.2A)
None
CRO  A 224 ( 4.9A)
None
None
 1.49A 4qi9A-3evpA:
undetectable		 4qi9A-3evpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		6 / 12 ALA A 268
LEU A 222
ILE A 172
LEU A 200
TYR A 250
THR A 266
 None
CRO  A 224 ( 4.2A)
None
CRO  A 224 ( 4.9A)
None
None
 1.43A 4x5iA-3evpA:
undetectable		 4x5iA-3evpA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NKN_A_LOCA201_2
(NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		3 / 3 VAL A 174
LYS A 271
MET A 246
 None
 1.08A 5nknA-3evpA:
undetectable		 5nknA-3evpA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		4 / 8 ILE A 294
GLN A  90
THR A 255
TYR A  95
 None
 0.85A 6cduD-3evpA:
undetectable
6cduE-3evpA:
undetectable		 6cduD-3evpA:
21.36
6cduE-3evpA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		4 / 8 ILE A 294
GLN A  90
THR A 255
TYR A  95
 None
 0.93A 6cduG-3evpA:
undetectable
6cduH-3evpA:
undetectable		 6cduG-3evpA:
21.36
6cduH-3evpA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 10 SER A 244
LEU A 114
SER A 230
ILE A  65
PRO A 109
 None
 1.50A 6dm1B-3evpA:
undetectable
6dm1C-3evpA:
undetectable		 6dm1B-3evpA:
15.52
6dm1C-3evpA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 10 SER A 244
LEU A 114
SER A 230
ILE A  65
PRO A 109
 None
 1.50A 6dm2B-3evpA:
undetectable
6dm2C-3evpA:
undetectable		 6dm2B-3evpA:
15.52
6dm2C-3evpA:
15.52