SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3evr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A29_A_TFPA153_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 8 ILE A 330
LEU A 335
MET A 354
MET A 374
 None
 0.43A 1a29A-3evrA:
18.5		 1a29A-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A29_A_TFPA153_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 8 ILE A 403
LEU A 408
GLU A 430
ALA A 431
VAL A 439
 None
 1.11A 1a29A-3evrA:
18.5		 1a29A-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A29_A_TFPA153_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 8 ILE A 403
LEU A 408
MET A 427
ALA A 431
VAL A 439
 None
 0.39A 1a29A-3evrA:
18.5		 1a29A-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A29_A_TFPA153_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 8 LEU A 408
MET A 427
ALA A 431
VAL A 439
MET A 447
 None
 1.05A 1a29A-3evrA:
18.5		 1a29A-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A29_A_TFPA154_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 10 MET A 412
LEU A 419
GLU A 423
GLU A 426
MET A 427
 None
 0.68A 1a29A-3evrA:
18.5		 1a29A-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 9 ILE A 403
LEU A 408
GLU A 426
ALA A 431
VAL A 439
 None
 1.30A 1ctrA-3evrA:
17.4		 1ctrA-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 9 ILE A 403
LEU A 408
MET A 427
ALA A 431
VAL A 439
 None
 0.54A 1ctrA-3evrA:
17.4		 1ctrA-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 9 LEU A 408
MET A 427
ALA A 431
VAL A 439
MET A 447
 None
 1.18A 1ctrA-3evrA:
17.4		 1ctrA-3evrA:
38.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		8 / 11 PHE A 322
ILE A 330
LEU A 335
MET A 339
LEU A 342
MET A 354
VAL A 358
MET A 374
 None
 0.66A 1dtlA-3evrA:
14.6		 1dtlA-3evrA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		6 / 11 PHE A 395
ILE A 403
LEU A 408
MET A 412
LEU A 415
MET A 427
 None
 0.57A 1dtlA-3evrA:
14.6		 1dtlA-3evrA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3003_1
(SERUM ALBUMIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 6 PHE A 322
ILE A 355
ALA A  53
MET A 375
 None
 1.18A 1hk2A-3evrA:
undetectable		 1hk2A-3evrA:
20.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIN_A_TFPA154_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 MET A 412
GLU A 417
LEU A 419
MET A 427
 None
 0.78A 1linA-3evrA:
18.7		 1linA-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIN_A_TFPA154_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 MET A 412
LEU A 419
GLU A 423
MET A 427
 None
 0.77A 1linA-3evrA:
18.7		 1linA-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIN_A_TFPA155_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 GLN A 311
GLU A 314
MET A 375
ALA A 376
 None
 1.27A 1linA-3evrA:
18.7		 1linA-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIN_A_TFPA155_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 GLN A 311
GLU A 314
MET A 375
PHE A 395
 None
 0.58A 1linA-3evrA:
18.7		 1linA-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIN_A_TFPA155_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 GLN A 311
GLU A 314
MET A 375
PHE A 444
 None
 1.09A 1linA-3evrA:
18.7		 1linA-3evrA:
38.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1LIN_A_TFPA155_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 GLN A 311
MET A 375
PHE A 395
MET A 448
 None
 1.15A 1linA-3evrA:
18.7		 1linA-3evrA:
38.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		7 / 12 ILE A 403
LEU A 408
MET A 412
LEU A 415
MET A 427
ILE A 428
VAL A 439
 None
 1.10A 1lxfC-3evrA:
8.9		 1lxfC-3evrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		6 / 12 PHE A 322
ILE A 330
LEU A 335
MET A 339
ILE A 355
MET A 374
 None
 1.20A 1lxfC-3evrA:
8.9		 1lxfC-3evrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		7 / 12 PHE A 395
ILE A 403
LEU A 408
ILE A 428
GLU A 430
VAL A 439
MET A 447
 None
 0.98A 1lxfC-3evrA:
8.9		 1lxfC-3evrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		8 / 12 PHE A 395
ILE A 403
LEU A 408
MET A 412
ILE A 428
VAL A 439
MET A 447
MET A 448
 None
 1.04A 1lxfC-3evrA:
8.9		 1lxfC-3evrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LXF_C_BEPC92_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		8 / 12 PHE A 395
ILE A 403
LEU A 408
MET A 412
MET A 427
ILE A 428
VAL A 439
MET A 448
 None
 1.13A 1lxfC-3evrA:
8.9		 1lxfC-3evrA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 7 ARG A 409
ALA A 406
ILE A 428
ILE A 403
GLU A 407
 None
None
None
None
CA  A   4 (-2.3A)
 1.48A 1oniD-3evrA:
undetectable
1oniF-3evrA:
undetectable		 1oniD-3evrA:
17.91
1oniF-3evrA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 10 HIS A  94
LEU A 211
LEU A 222
THR A 220
THR A 221
 None
None
CRO  A 224 ( 4.2A)
CRO  A 224 ( 4.6A)
None
 1.41A 1rj6A-3evrA:
undetectable		 1rj6A-3evrA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 10 HIS A  94
LEU A 211
LEU A 222
THR A 220
THR A 221
 None
None
CRO  A 224 ( 4.2A)
CRO  A 224 ( 4.6A)
None
 1.39A 1rj6B-3evrA:
undetectable		 1rj6B-3evrA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 8 ILE A 256
ASP A 287
GLY A 262
PHE A 258
 None
 0.83A 1rtsA-3evrA:
undetectable		 1rtsA-3evrA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 ILE A 256
ASP A 287
GLY A 262
PHE A 258
 None
 0.83A 1rtsB-3evrA:
undetectable		 1rtsB-3evrA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 5 PHE A 395
LEU A 415
PHE A 444
MET A 448
 None
 1.26A 1wrlC-3evrA:
9.9		 1wrlC-3evrA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 8 LEU A 307
PHE A 315
PHE A 371
MET A 375
 None
 0.80A 1wrlC-3evrA:
9.9
1wrlD-3evrA:
9.7		 1wrlC-3evrA:
18.81
1wrlD-3evrA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 GLY A 362
THR A 143
ASP A 361
ASN A 363
 None
None
CA  A   1 (-3.0A)
CA  A   1 (-3.0A)
 1.03A 2g70A-3evrA:
undetectable		 2g70A-3evrA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 GLY A 362
THR A 143
ASP A 361
ASN A 363
 None
None
CA  A   1 (-3.0A)
CA  A   1 (-3.0A)
 1.04A 2g70B-3evrA:
undetectable		 2g70B-3evrA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 12 SER A 230
THR A 116
THR A 303
VAL A 219
VAL A 174
 None
CRO  A 224 ( 3.1A)
None
CRO  A 224 ( 4.6A)
None
 1.28A 2nniA-3evrA:
undetectable		 2nniA-3evrA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		3 / 3 ASN A  83
LEU A 299
HIS A  82
 None
 0.81A 2q6fB-3evrA:
undetectable		 2q6fB-3evrA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 12 LEU A 202
LEU A 200
ILE A 172
ALA A 195
PHE A 229
 CRO  A 224 ( 4.7A)
None
None
None
None
 1.16A 2qb4A-3evrA:
undetectable		 2qb4A-3evrA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 12 MET A 354
ASN A 345
LEU A  57
ILE A  54
ALA A  53
 None
 0.95A 3a50A-3evrA:
undetectable		 3a50A-3evrA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 4 ARG A 377
ASP A 367
GLY A 362
THR A 138
 CRO  A 224 ( 4.9A)
CA  A   1 (-3.5A)
None
None
 1.30A 3k4vB-3evrA:
undetectable		 3k4vB-3evrA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 6 ILE A 101
PHE A 241
ALA A 245
ASN A  98
 None
 1.14A 3pgyA-3evrA:
undetectable
3pgyB-3evrA:
undetectable		 3pgyA-3evrA:
23.55
3pgyB-3evrA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 9 PHE A 229
VAL A 270
ASN A 279
ILE A 172
PHE A 166
 None
CRO  A 224 ( 4.8A)
CRO  A 224 ( 3.6A)
None
None
 1.20A 3t3rB-3evrA:
undetectable		 3t3rB-3evrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 9 PHE A 229
VAL A 270
ASN A 279
ILE A 172
PHE A 166
 None
CRO  A 224 ( 4.8A)
CRO  A 224 ( 3.6A)
None
None
 1.23A 3t3rC-3evrA:
undetectable		 3t3rC-3evrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 10 PHE A 229
VAL A 270
ASN A 279
ILE A 172
PHE A 166
 None
CRO  A 224 ( 4.8A)
CRO  A 224 ( 3.6A)
None
None
 1.19A 3t3rD-3evrA:
undetectable		 3t3rD-3evrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 ILE A 256
ASP A 287
GLY A 262
PHE A 258
 None
 0.91A 4iqqA-3evrA:
undetectable		 4iqqA-3evrA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA506_0
(RNA POLYMERASE
3D-POL)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		3 / 3 VAL A 180
GLY A 182
LYS A 184
 None
 0.76A 4k50A-3evrA:
undetectable		 4k50A-3evrA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		3 / 3 VAL A 180
GLY A 182
LYS A 184
 None
 0.76A 4k50I-3evrA:
undetectable		 4k50I-3evrA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 6 VAL A 213
LEU A 211
LEU A 283
PHE A  78
 None
None
None
CRO  A 224 ( 4.5A)
 0.93A 4o1zA-3evrA:
undetectable		 4o1zA-3evrA:
21.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 8 ILE A 403
LEU A 408
MET A 412
ALA A 431
VAL A 439
 None
 0.47A 4rjdA-3evrA:
13.1		 4rjdA-3evrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 8 PHE A 322
ILE A 330
LEU A 335
MET A 354
 None
 0.42A 4rjdA-3evrA:
13.1		 4rjdA-3evrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 8 PHE A 322
ILE A 330
LEU A 335
MET A 374
 None
 0.52A 4rjdA-3evrA:
13.1		 4rjdA-3evrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		6 / 8 PHE A 395
ILE A 403
LEU A 408
MET A 427
ALA A 431
VAL A 439
 None
 0.48A 4rjdA-3evrA:
13.1		 4rjdA-3evrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_A_TFPA203_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 8 PHE A 395
MET A 427
ALA A 431
VAL A 439
MET A 447
 None
 0.96A 4rjdA-3evrA:
13.1		 4rjdA-3evrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 7 PHE A 322
LEU A 335
MET A 354
MET A 374
MET A 375
 None
 0.72A 4rjdB-3evrA:
11.1		 4rjdB-3evrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 7 PHE A 395
LEU A 408
MET A 412
ALA A 431
MET A 447
 None
 1.08A 4rjdB-3evrA:
11.1		 4rjdB-3evrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 7 PHE A 395
LEU A 408
MET A 412
ALA A 431
MET A 448
 None
 0.85A 4rjdB-3evrA:
11.1		 4rjdB-3evrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 7 PHE A 395
LEU A 408
MET A 427
ALA A 431
MET A 447
 None
 1.00A 4rjdB-3evrA:
11.1		 4rjdB-3evrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 7 PHE A 395
LEU A 408
MET A 427
ALA A 431
MET A 448
 None
 0.66A 4rjdB-3evrA:
11.1		 4rjdB-3evrA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 ILE A 256
ASP A 287
GLY A 262
PHE A 258
 None
 0.86A 5h3aA-3evrA:
undetectable		 5h3aA-3evrA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MM4_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 10 LEU A 307
HIS A  49
ALA A 318
PHE A 371
THR A 373
 None
 1.43A 5mm4B-3evrA:
undetectable		 5mm4B-3evrA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		6 / 10 LEU A 335
MET A 354
GLU A 357
VAL A 358
ILE A 366
MET A 375
 None
 0.87A 5v02B-3evrA:
undetectable
5v02R-3evrA:
12.4		 5v02B-3evrA:
12.59
5v02R-3evrA:
38.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_A_SAMA601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 5 PHE A 371
THR A 329
ASP A 361
ASN A  62
 None
None
CA  A   1 (-3.0A)
None
 1.08A 5ybbA-3evrA:
undetectable		 5ybbA-3evrA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 PHE A  78
SER A 115
VAL A 137
ARG A 254
 CRO  A 224 ( 4.5A)
None
None
CRO  A 224 ( 3.0A)
 1.38A 6av6C-3evrA:
undetectable
6av6D-3evrA:
undetectable		 6av6C-3evrA:
11.75
6av6D-3evrA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 8 ILE A 294
GLN A  90
THR A 255
TYR A  95
 None
 0.87A 6cduD-3evrA:
undetectable
6cduE-3evrA:
undetectable		 6cduD-3evrA:
21.68
6cduE-3evrA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 10 SER A 244
LEU A 114
SER A 230
ILE A  65
PRO A 109
 None
 1.50A 6dlzB-3evrA:
undetectable
6dlzC-3evrA:
undetectable		 6dlzB-3evrA:
12.35
6dlzC-3evrA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 10 SER A 244
LEU A 114
SER A 230
ILE A  65
PRO A 109
 None
 1.49A 6dm1B-3evrA:
undetectable
6dm1C-3evrA:
undetectable		 6dm1B-3evrA:
12.35
6dm1C-3evrA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 10 SER A 244
LEU A 114
SER A 230
ILE A  65
PRO A 109
 None
 1.49A 6dm2B-3evrA:
undetectable
6dm2C-3evrA:
undetectable		 6dm2B-3evrA:
12.35
6dm2C-3evrA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 10 ILE A  65
PRO A 109
SER A 244
LEU A 114
SER A 230
 None
 1.50A 6dm2A-3evrA:
undetectable
6dm2D-3evrA:
undetectable		 6dm2A-3evrA:
12.35
6dm2D-3evrA:
12.35