SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3evt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3evt PHOSPHOGLYCERATE
DEHYDROGENASE
(Lactobacillus
plantarum) 		4 / 7 VAL A 163
GLY A 165
THR A 145
ILE A 142
 None
 0.80A 1gtnC-3evtA:
undetectable
1gtnD-3evtA:
undetectable		 1gtnC-3evtA:
13.23
1gtnD-3evtA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_A_SALA1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3evt PHOSPHOGLYCERATE
DEHYDROGENASE
(Lactobacillus
plantarum) 		5 / 9 ILE A 142
GLY A 144
TYR A 143
GLY A 227
PHE A 209
 None
 1.06A 2y7wA-3evtA:
1.2		 2y7wA-3evtA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3evt PHOSPHOGLYCERATE
DEHYDROGENASE
(Lactobacillus
plantarum) 		4 / 5 PRO A 200
THR A 179
VAL A 180
GLY A 170
 None
 1.14A 3elzA-3evtA:
undetectable		 3elzA-3evtA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 3evt PHOSPHOGLYCERATE
DEHYDROGENASE
(Lactobacillus
plantarum) 		4 / 6 LEU A 128
MET A 130
THR A 132
ARG A 111
 None
 1.22A 3thrB-3evtA:
6.6		 3thrB-3evtA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 3evt PHOSPHOGLYCERATE
DEHYDROGENASE
(Lactobacillus
plantarum) 		3 / 3 PRO A 260
LEU A 259
GLN A 267
 None
 0.56A 4pevB-3evtA:
2.1		 4pevB-3evtA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3evt PHOSPHOGLYCERATE
DEHYDROGENASE
(Lactobacillus
plantarum) 		4 / 7 ASN A  60
LEU A  55
LEU A  51
LEU A  80
 None
 0.82A 4wg0L-3evtA:
undetectable
4wg0M-3evtA:
undetectable		 4wg0L-3evtA:
3.96
4wg0M-3evtA:
3.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3evt PHOSPHOGLYCERATE
DEHYDROGENASE
(Lactobacillus
plantarum) 		5 / 9 PHE A 209
LEU A 141
VAL A 166
GLY A 165
THR A 145
 None
 1.41A 5cp4A-3evtA:
undetectable		 5cp4A-3evtA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_C_REAC602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 3evt PHOSPHOGLYCERATE
DEHYDROGENASE
(Lactobacillus
plantarum) 		5 / 10 THR A 217
LEU A 213
ASN A 225
LEU A 223
LEU A 246
 None
 1.04A 5fhzC-3evtA:
undetectable		 5fhzC-3evtA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3evt PHOSPHOGLYCERATE
DEHYDROGENASE
(Lactobacillus
plantarum) 		4 / 8 HIS A 162
GLN A 150
GLY A 149
LEU A 152
 None
 0.77A 5w3jB-3evtA:
undetectable		 5w3jB-3evtA:
20.09