SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ew2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		4 / 7 ASN A  21
SER A  25
TYR A  41
TRP A  85
 BTN  A 400 (-3.6A)
BTN  A 400 (-2.6A)
BTN  A 400 (-4.4A)
BTN  A 400 ( 4.7A)
 0.22A 2uz2A-3ew2A:
14.7		 2uz2A-3ew2A:
28.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 VAL A  99
TRP A  85
TRP A 102
 None
BTN  A 400 ( 4.7A)
BTN  A 400 (-3.3A)
 1.03A 2xdcA-3ew2A:
undetectable
2xdcB-3ew2A:
undetectable		 2xdcA-3ew2A:
13.64
2xdcB-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 VAL A  99
TRP A 102
TRP A  85
 None
BTN  A 400 (-3.3A)
BTN  A 400 ( 4.7A)
 0.96A 2xdcA-3ew2A:
undetectable
2xdcB-3ew2A:
undetectable		 2xdcA-3ew2A:
13.64
2xdcB-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 TRP A  85
VAL A  99
TRP A 102
 BTN  A 400 ( 4.7A)
None
BTN  A 400 (-3.3A)
 0.95A 2xdcA-3ew2A:
undetectable
2xdcB-3ew2A:
undetectable		 2xdcA-3ew2A:
13.64
2xdcB-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 TRP A 102
VAL A  99
TRP A  85
 BTN  A 400 (-3.3A)
None
BTN  A 400 ( 4.7A)
 1.04A 2xdcA-3ew2A:
undetectable
2xdcB-3ew2A:
undetectable		 2xdcA-3ew2A:
13.64
2xdcB-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 VAL A  99
TRP A  85
TRP A 102
 None
BTN  A 400 ( 4.7A)
BTN  A 400 (-3.3A)
 1.16A 2xdcC-3ew2A:
undetectable
2xdcD-3ew2A:
undetectable		 2xdcC-3ew2A:
13.64
2xdcD-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 VAL A  99
TRP A 102
TRP A  85
 None
BTN  A 400 (-3.3A)
BTN  A 400 ( 4.7A)
 0.88A 2xdcC-3ew2A:
undetectable
2xdcD-3ew2A:
undetectable		 2xdcC-3ew2A:
13.64
2xdcD-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 TRP A  85
VAL A  99
TRP A 102
 BTN  A 400 ( 4.7A)
None
BTN  A 400 (-3.3A)
 1.20A 2xdcC-3ew2A:
undetectable
2xdcD-3ew2A:
undetectable		 2xdcC-3ew2A:
13.64
2xdcD-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 TRP A  85
VAL A  99
TRP A 102
 BTN  A 400 ( 4.7A)
None
BTN  A 400 (-3.3A)
 1.17A 2xdcE-3ew2A:
undetectable
2xdcF-3ew2A:
undetectable		 2xdcE-3ew2A:
13.64
2xdcF-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 VAL A  99
TRP A  85
TRP A 102
 None
BTN  A 400 ( 4.7A)
BTN  A 400 (-3.3A)
 1.05A 2y5mA-3ew2A:
undetectable
2y5mB-3ew2A:
undetectable		 2y5mA-3ew2A:
13.64
2y5mB-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 VAL A  99
TRP A 102
TRP A  85
 None
BTN  A 400 (-3.3A)
BTN  A 400 ( 4.7A)
 0.96A 2y5mA-3ew2A:
undetectable
2y5mB-3ew2A:
undetectable		 2y5mA-3ew2A:
13.64
2y5mB-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 TRP A  85
VAL A  99
TRP A 102
 BTN  A 400 ( 4.7A)
None
BTN  A 400 (-3.3A)
 1.18A 2y5mE-3ew2A:
undetectable
2y5mF-3ew2A:
undetectable		 2y5mE-3ew2A:
13.64
2y5mF-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 VAL A  99
TRP A  85
TRP A 102
 None
BTN  A 400 ( 4.7A)
BTN  A 400 (-3.3A)
 1.05A 2y6nA-3ew2A:
undetectable
2y6nB-3ew2A:
undetectable		 2y6nA-3ew2A:
13.64
2y6nB-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 VAL A  99
TRP A 102
TRP A  85
 None
BTN  A 400 (-3.3A)
BTN  A 400 ( 4.7A)
 0.97A 2y6nA-3ew2A:
undetectable
2y6nB-3ew2A:
undetectable		 2y6nA-3ew2A:
13.64
2y6nB-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 TRP A  85
VAL A  99
TRP A 102
 BTN  A 400 ( 4.7A)
None
BTN  A 400 (-3.3A)
 0.98A 2y6nA-3ew2A:
undetectable
2y6nB-3ew2A:
undetectable		 2y6nA-3ew2A:
13.64
2y6nB-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 TRP A 102
VAL A  99
TRP A  85
 BTN  A 400 (-3.3A)
None
BTN  A 400 ( 4.7A)
 1.03A 2y6nA-3ew2A:
undetectable
2y6nB-3ew2A:
undetectable		 2y6nA-3ew2A:
13.64
2y6nB-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 TRP A  85
VAL A  99
TRP A 102
 BTN  A 400 ( 4.7A)
None
BTN  A 400 (-3.3A)
 1.17A 2y6nC-3ew2A:
undetectable
2y6nD-3ew2A:
undetectable		 2y6nC-3ew2A:
13.64
2y6nD-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 TRP A  85
VAL A  99
TRP A 102
 BTN  A 400 ( 4.7A)
None
BTN  A 400 (-3.3A)
 1.18A 2y6nE-3ew2A:
undetectable
2y6nF-3ew2A:
undetectable		 2y6nE-3ew2A:
13.64
2y6nF-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 VAL A  99
TRP A  85
TRP A 102
 None
BTN  A 400 ( 4.7A)
BTN  A 400 (-3.3A)
 1.12A 3zq8A-3ew2A:
undetectable
3zq8B-3ew2A:
undetectable		 3zq8A-3ew2A:
13.64
3zq8B-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		3 / 3 VAL A  99
TRP A 102
TRP A  85
 None
BTN  A 400 (-3.3A)
BTN  A 400 ( 4.7A)
 0.81A 3zq8A-3ew2A:
undetectable
3zq8B-3ew2A:
undetectable		 3zq8A-3ew2A:
13.64
3zq8B-3ew2A:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		4 / 5 THR A 120
THR A 100
THR A  64
ASN A  92
 None
 1.39A 4pgfB-3ew2A:
undetectable		 4pgfB-3ew2A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 3ew2 RHIZAVIDIN
(Rhizobium
etli) 		5 / 11 PHE A  65
GLY A  87
GLN A  90
GLU A  97
THR A  96
 None
 1.36A 5x1bG-3ew2A:
0.0
5x1bN-3ew2A:
undetectable
5x1bO-3ew2A:
0.0		 5x1bG-3ew2A:
18.98
5x1bN-3ew2A:
13.65
5x1bO-3ew2A:
20.72