SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ew7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3ew7 LMO0794 PROTEIN
(Listeria
monocytogenes) 		6 / 11 GLY A   7
ALA A  68
ASP A  67
VAL A 194
GLY A   4
ILE A  16
 None
 1.34A 1sdvB-3ew7A:
undetectable		 1sdvB-3ew7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 3ew7 LMO0794 PROTEIN
(Listeria
monocytogenes) 		6 / 12 GLY A   7
ALA A  68
ASP A  67
VAL A 194
GLY A   4
ILE A  16
 None
 1.38A 2avoB-3ew7A:
undetectable		 2avoB-3ew7A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1103_0
(FERROCHELATASE)		 3ew7 LMO0794 PROTEIN
(Listeria
monocytogenes) 		4 / 8 ARG A  11
SER A  82
VAL A 101
GLY A 102
 None
 1.11A 2qd5B-3ew7A:
3.3		 2qd5B-3ew7A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 3ew7 LMO0794 PROTEIN
(Listeria
monocytogenes) 		6 / 12 GLY A   7
ALA A  68
ASP A  67
VAL A 194
GLY A   4
ILE A  16
 None
 1.34A 2r5pB-3ew7A:
undetectable		 2r5pB-3ew7A:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 3ew7 LMO0794 PROTEIN
(Listeria
monocytogenes) 		4 / 4 LEU A  90
SER A  88
LEU A  83
LEU A  59
 None
 1.12A 4n09A-3ew7A:
7.2		 4n09A-3ew7A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_2
(ANDROGEN RECEPTOR)		 3ew7 LMO0794 PROTEIN
(Listeria
monocytogenes) 		4 / 8 LEU A 204
ASN A 205
LEU A  99
ILE A  87
 None
 0.96A 4ok1A-3ew7A:
undetectable		 4ok1A-3ew7A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3ew7 LMO0794 PROTEIN
(Listeria
monocytogenes) 		4 / 7 VAL A 194
ILE A 198
LEU A  86
LEU A  98
 None
 1.00A 4xo7A-3ew7A:
undetectable		 4xo7A-3ew7A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 3ew7 LMO0794 PROTEIN
(Listeria
monocytogenes) 		4 / 8 TYR A 190
SER A 154
THR A 209
PRO A 129
 None
 1.00A 5jhdE-3ew7A:
undetectable
5jhdG-3ew7A:
undetectable		 5jhdE-3ew7A:
21.37
5jhdG-3ew7A:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3ew7 LMO0794 PROTEIN
(Listeria
monocytogenes) 		4 / 5 TRP A 150
LEU A  98
VAL A 100
LEU A  83
 None
 0.89A 5xooB-3ew7A:
undetectable		 5xooB-3ew7A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_E_LLLE301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3ew7 LMO0794 PROTEIN
(Listeria
monocytogenes) 		4 / 7 ASP A  74
ARG A  32
TYR A  69
ASP A  50
 None
 1.27A 6mn5E-3ew7A:
undetectable		 6mn5E-3ew7A:
20.00