SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ewe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 3ewe NUCLEOPORIN NUP85
(Saccharomyces
cerevisiae) 		4 / 6 HIS B 403
ILE B 402
LYS B 427
ALA B 426
 None
 0.93A 1hk1A-3eweB:
3.1		 1hk1A-3eweB:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 3ewe NUCLEOPORIN NUP85
(Saccharomyces
cerevisiae) 		3 / 3 ASP B  99
PHE B 158
ARG B 171
 None
 0.78A 2a3aA-3eweB:
undetectable		 2a3aA-3eweB:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 3ewe NUCLEOPORIN NUP85
(Saccharomyces
cerevisiae) 		4 / 8 SER B 207
ARG B 186
PHE B 204
ASN B 210
 None
 1.18A 3n62A-3eweB:
undetectable		 3n62A-3eweB:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9H_A_NCAA1163_0
(TANKYRASE-2)		 3ewe NUCLEOPORIN NUP85
(Saccharomyces
cerevisiae) 		4 / 8 GLY B 460
TYR B 457
SER B 463
TYR B 464
 None
 0.90A 3u9hA-3eweB:
undetectable		 3u9hA-3eweB:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_C_MIYC392_1
(TETX2 PROTEIN)		 3ewe NUCLEOPORIN NUP85
(Saccharomyces
cerevisiae) 		5 / 12 PRO B 407
GLU B 410
VAL B 181
ILE B 405
GLU B 174
 None
 1.35A 4a99A-3eweB:
undetectable
4a99C-3eweB:
undetectable		 4a99A-3eweB:
21.65
4a99C-3eweB:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 3ewe NUCLEOPORIN NUP85
(Saccharomyces
cerevisiae) 		4 / 7 ASN B 250
LEU B 254
GLY B 340
TYR B 363
 None
 0.99A 4cp3A-3eweB:
undetectable
4cp3B-3eweB:
undetectable		 4cp3A-3eweB:
14.90
4cp3B-3eweB:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 3ewe NUCLEOPORIN NUP85
(Saccharomyces
cerevisiae) 		3 / 3 ASP B 330
ASP B 334
ASN B 342
 None
 0.79A 4q5mA-3eweB:
undetectable		 4q5mA-3eweB:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ewe NUCLEOPORIN NUP85
(Saccharomyces
cerevisiae) 		4 / 5 LEU B 362
PHE B 360
LEU B 208
PHE B 204
 None
 1.21A 5iy5P-3eweB:
2.8
5iy5W-3eweB:
undetectable		 5iy5P-3eweB:
18.58
5iy5W-3eweB:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ewe NUCLEOPORIN NUP85
(Saccharomyces
cerevisiae) 		4 / 6 LEU B 362
PHE B 360
LEU B 208
PHE B 204
 None
 1.13A 5w97C-3eweB:
undetectable
5w97J-3eweB:
undetectable		 5w97C-3eweB:
18.94
5w97J-3eweB:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ewe NUCLEOPORIN NUP85
(Saccharomyces
cerevisiae) 		4 / 5 LEU B 362
PHE B 360
LEU B 208
PHE B 204
 None
 1.18A 5x1fC-3eweB:
2.4
5x1fJ-3eweB:
undetectable		 5x1fC-3eweB:
18.94
5x1fJ-3eweB:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3ewe NUCLEOPORIN NUP85
(Saccharomyces
cerevisiae) 		4 / 5 LEU B 362
PHE B 360
LEU B 208
PHE B 204
 None
 1.22A 5xdxC-3eweB:
2.9
5xdxJ-3eweB:
undetectable		 5xdxC-3eweB:
19.52
5xdxJ-3eweB:
7.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3ewe NUCLEOPORIN NUP85
(Saccharomyces
cerevisiae) 		4 / 5 LEU B 362
PHE B 360
LEU B 208
PHE B 204
 None
 1.25A 5xdxP-3eweB:
2.8
5xdxW-3eweB:
undetectable		 5xdxP-3eweB:
19.52
5xdxW-3eweB:
7.80