SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ewm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.36A 1bx4A-3ewmA:
29.1		 1bx4A-3ewmA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
ASP A 247
 None
 0.89A 1bx4A-3ewmA:
29.1		 1bx4A-3ewmA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 THR A 215
GLY A 217
ALA A 245
GLY A 246
ALA A 276
 None
 0.43A 1bx4A-3ewmA:
29.1		 1bx4A-3ewmA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		4 / 7 LEU A 263
LEU A 258
GLY A 256
LEU A 253
 None
 0.93A 1gtiB-3ewmA:
undetectable		 1gtiB-3ewmA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 ASP A  13
LEU A 167
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.75A 1liiA-3ewmA:
29.2		 1liiA-3ewmA:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 ASP A  13
LEU A 167
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.78A 1likA-3ewmA:
29.0		 1likA-3ewmA:
26.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.32A 2c49A-3ewmA:
30.0		 2c49A-3ewmA:
29.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		4 / 7 ASP A  13
GLY A  33
GLY A  34
ASN A  38
 None
 0.38A 2c49B-3ewmA:
30.1		 2c49B-3ewmA:
29.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.31A 2pkkA-3ewmA:
29.2		 2pkkA-3ewmA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.33A 2pkmA-3ewmA:
29.2		 2pkmA-3ewmA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
GLY A 244
ASP A 247
 None
 0.75A 2pkmA-3ewmA:
29.2		 2pkmA-3ewmA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_B_P1BB1475_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		4 / 6 LEU A 199
ILE A 183
ILE A 257
LEU A 223
 None
 0.93A 2xkwB-3ewmA:
undetectable		 2xkwB-3ewmA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		4 / 5 ILE A  15
HIS A  31
ARG A 283
GLY A 284
 None
 1.07A 3b9mA-3ewmA:
undetectable		 3b9mA-3ewmA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		4 / 8 PHE A  61
GLY A  62
VAL A  56
LEU A  10
 None
 0.93A 3bgdB-3ewmA:
3.7		 3bgdB-3ewmA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		4 / 8 ILE A 117
PRO A 139
ASN A 138
GLY A   8
 None
 0.93A 3em0B-3ewmA:
undetectable		 3em0B-3ewmA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		4 / 4 GLY A  34
GLU A   9
ASP A 160
ASP A  13
 None
 1.30A 3mb5A-3ewmA:
3.5		 3mb5A-3ewmA:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		3 / 3 VAL A 161
SER A 132
LEU A 163
 None
 0.66A 3n8xA-3ewmA:
0.9		 3n8xA-3ewmA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPS_A_CHDA211_0
(CMER)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 10 LEU A 211
PHE A 249
ALA A 272
GLY A 256
ILE A 257
 None
 1.50A 3qpsA-3ewmA:
undetectable		 3qpsA-3ewmA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 9 ALA A 108
VAL A  80
GLY A   8
ILE A 134
THR A 113
 None
 1.34A 3spkA-3ewmA:
undetectable		 3spkA-3ewmA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.38A 3uboA-3ewmA:
32.4		 3uboA-3ewmA:
28.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ASN A  38
GLY A 244
ASP A 247
 None
 0.82A 3uboA-3ewmA:
32.4		 3uboA-3ewmA:
28.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.08A 3uboB-3ewmA:
33.1		 3uboB-3ewmA:
28.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 167
THR A 243
ASP A 247
 None
 1.19A 3uboB-3ewmA:
33.1		 3uboB-3ewmA:
28.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.40A 3uq6A-3ewmA:
31.2		 3uq6A-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
VAL A  90
 None
 0.49A 3uq6A-3ewmA:
31.2		 3uq6A-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
GLY A 244
ASP A 247
 None
 0.90A 3uq6A-3ewmA:
31.2		 3uq6A-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ALA A  35
ASN A  38
LEU A 103
GLY A 244
ASP A 247
 None
 0.94A 3uq6B-3ewmA:
30.3		 3uq6B-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ALA A  35
ASN A  38
ASP A 247
 None
 0.36A 3uq6B-3ewmA:
30.3		 3uq6B-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ALA A  35
ASN A  38
VAL A  90
 None
 0.57A 3uq6B-3ewmA:
30.3		 3uq6B-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  34
ALA A  35
ASN A  38
LEU A 103
ASP A 247
 None
 0.88A 3uq6B-3ewmA:
30.3		 3uq6B-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_1
(ADENOSINE KINASE,
PUTATIVE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 LEU A 167
ALA A  35
LEU A 103
GLY A 246
ASP A 247
 None
 1.10A 3uq6B-3ewmA:
30.3		 3uq6B-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		4 / 5 LEU A  11
GLY A  34
PHE A 110
ASN A 162
 None
 1.23A 3uq6B-3ewmA:
30.3		 3uq6B-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ALA A   5
LEU A 254
MET A 250
ILE A 157
ILE A 188
 None
 1.11A 3ut5B-3ewmA:
6.1		 3ut5B-3ewmA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.45A 3vaqA-3ewmA:
30.9		 3vaqA-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
VAL A  90
 None
 0.47A 3vaqA-3ewmA:
30.9		 3vaqA-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
GLY A 244
ASP A 247
 None
 0.91A 3vaqA-3ewmA:
30.9		 3vaqA-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ALA A  35
ASN A  38
ASP A 247
 None
 0.39A 3vaqB-3ewmA:
29.9		 3vaqB-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ALA A  35
ASN A  38
VAL A  90
 None
 0.54A 3vaqB-3ewmA:
29.9		 3vaqB-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  34
ALA A  35
ASN A  38
LEU A 103
ASP A 247
 None
 0.92A 3vaqB-3ewmA:
29.9		 3vaqB-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  34
ALA A  35
ASN A  38
LEU A 103
GLY A 244
 None
 1.07A 3vaqB-3ewmA:
29.9		 3vaqB-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 LEU A 167
ALA A  35
LEU A 103
GLY A 246
ASP A 247
 None
 1.11A 3vaqB-3ewmA:
29.9		 3vaqB-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.37A 3vasA-3ewmA:
31.1		 3vasA-3ewmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
VAL A  90
 None
 0.45A 3vasA-3ewmA:
31.1		 3vasA-3ewmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
GLY A 244
ASP A 247
 None
 0.90A 3vasA-3ewmA:
31.1		 3vasA-3ewmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 LEU A 167
GLY A  33
GLY A  34
ASN A  38
VAL A  90
 None
 0.97A 3vasA-3ewmA:
31.1		 3vasA-3ewmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.31A 3vasB-3ewmA:
22.5		 3vasB-3ewmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
VAL A  90
 None
 0.42A 3vasB-3ewmA:
22.5		 3vasB-3ewmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
GLY A 244
ASP A 247
 None
 0.89A 3vasB-3ewmA:
22.5		 3vasB-3ewmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 LEU A 167
GLY A  33
GLY A  34
ASN A  38
VAL A  90
 None
 0.93A 3vasB-3ewmA:
22.5		 3vasB-3ewmA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 ASP A  13
ALA A  35
ASN A  38
LEU A 167
GLY A 244
ASP A 247
 None
 1.12A 4dc3A-3ewmA:
30.0		 4dc3A-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		7 / 12 ASP A  13
LEU A 167
GLY A  33
ALA A  35
ASN A  38
GLY A 244
ASP A 247
 None
 1.07A 4dc3A-3ewmA:
30.0		 4dc3A-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		7 / 12 ASP A  13
LEU A 167
GLY A  33
ALA A  35
ASN A  38
VAL A  90
ASP A 247
 None
 0.89A 4dc3A-3ewmA:
30.0		 4dc3A-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 LEU A 167
ALA A  35
ASN A  38
LEU A 103
GLY A 246
ASP A 247
 None
 1.43A 4dc3A-3ewmA:
30.0		 4dc3A-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		7 / 12 ASP A  13
LEU A 167
GLY A  33
GLY A  34
ASN A  38
GLY A 244
ASP A 247
 None
 1.03A 4dc3B-3ewmA:
31.0		 4dc3B-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		7 / 12 ASP A  13
LEU A 167
GLY A  33
GLY A  34
ASN A  38
VAL A  90
ASP A 247
 None
 0.93A 4dc3B-3ewmA:
31.0		 4dc3B-3ewmA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.36A 4e3aA-3ewmA:
33.4		 4e3aA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.10A 4e3aA-3ewmA:
33.4		 4e3aA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
ASP A 247
 None
 1.02A 4e3aA-3ewmA:
33.4		 4e3aA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.39A 4e3aB-3ewmA:
33.3		 4e3aB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
GLY A 244
ASP A 247
 None
 1.13A 4e3aB-3ewmA:
33.3		 4e3aB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  34
ASN A  38
LEU A 103
THR A 243
GLY A 244
ASP A 247
 None
 1.15A 4e3aB-3ewmA:
33.3		 4e3aB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  34
ASN A  38
LEU A 167
THR A 243
GLY A 244
ASP A 247
 None
 1.20A 4e3aB-3ewmA:
33.3		 4e3aB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.36A 4jksA-3ewmA:
33.5		 4jksA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.73A 4jksA-3ewmA:
33.5		 4jksA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.35A 4jksB-3ewmA:
33.5		 4jksB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.73A 4jksB-3ewmA:
33.5		 4jksB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.34A 4jkuA-3ewmA:
33.5		 4jkuA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.71A 4jkuA-3ewmA:
33.5		 4jkuA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.07A 4jkuB-3ewmA:
33.4		 4jkuB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 167
THR A 243
ASP A 247
 None
 1.20A 4jkuB-3ewmA:
33.4		 4jkuB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.35A 4k8cA-3ewmA:
33.4		 4k8cA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.73A 4k8cA-3ewmA:
33.4		 4k8cA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.35A 4k8cB-3ewmA:
33.4		 4k8cB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.72A 4k8cB-3ewmA:
33.4		 4k8cB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.37A 4k8kA-3ewmA:
33.4		 4k8kA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.73A 4k8kA-3ewmA:
33.4		 4k8kA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.35A 4k8kB-3ewmA:
33.4		 4k8kB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.73A 4k8kB-3ewmA:
33.4		 4k8kB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.36A 4k8pA-3ewmA:
33.4		 4k8pA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
ASP A 247
 None
 1.03A 4k8pA-3ewmA:
33.4		 4k8pA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.72A 4k8pA-3ewmA:
33.4		 4k8pA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.35A 4k8pB-3ewmA:
33.4		 4k8pB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.09A 4k8pB-3ewmA:
33.4		 4k8pB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
ASP A 247
 None
 1.01A 4k8pB-3ewmA:
33.4		 4k8pB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.70A 4k8pB-3ewmA:
33.4		 4k8pB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.39A 4k8tA-3ewmA:
33.3		 4k8tA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.09A 4k8tA-3ewmA:
33.3		 4k8tA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
THR A 243
ASP A 247
 None
 1.11A 4k8tA-3ewmA:
33.3		 4k8tA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.38A 4k8tB-3ewmA:
33.4		 4k8tB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
THR A 243
ASP A 247
 None
 1.10A 4k8tB-3ewmA:
33.4		 4k8tB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.36A 4k93A-3ewmA:
33.5		 4k93A-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.10A 4k93A-3ewmA:
33.5		 4k93A-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
THR A 243
ASP A 247
 None
 1.11A 4k93A-3ewmA:
33.5		 4k93A-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.36A 4k93B-3ewmA:
33.5		 4k93B-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.09A 4k93B-3ewmA:
33.5		 4k93B-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
THR A 243
ASP A 247
 None
 1.10A 4k93B-3ewmA:
33.5		 4k93B-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.08A 4k9cA-3ewmA:
33.5		 4k9cA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 167
THR A 243
ASP A 247
 None
 1.21A 4k9cA-3ewmA:
33.5		 4k9cA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.07A 4k9cB-3ewmA:
33.5		 4k9cB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 167
THR A 243
ASP A 247
 None
 1.20A 4k9cB-3ewmA:
33.5		 4k9cB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.37A 4k9iA-3ewmA:
33.5		 4k9iA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.10A 4k9iA-3ewmA:
33.5		 4k9iA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
THR A 243
ASP A 247
 None
 1.10A 4k9iA-3ewmA:
33.5		 4k9iA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.37A 4k9iB-3ewmA:
33.5		 4k9iB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
THR A 243
ASP A 247
 None
 1.11A 4k9iB-3ewmA:
33.5		 4k9iB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.08A 4kadA-3ewmA:
33.5		 4kadA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 167
THR A 243
ASP A 247
 None
 1.20A 4kadA-3ewmA:
33.5		 4kadA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.35A 4kadB-3ewmA:
33.4		 4kadB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.09A 4kadB-3ewmA:
33.4		 4kadB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
THR A 243
ASP A 247
 None
 1.10A 4kadB-3ewmA:
33.4		 4kadB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.36A 4kahA-3ewmA:
33.5		 4kahA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.72A 4kahA-3ewmA:
33.5		 4kahA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.35A 4kahB-3ewmA:
33.5		 4kahB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.72A 4kahB-3ewmA:
33.5		 4kahB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.36A 4kalA-3ewmA:
33.5		 4kalA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.71A 4kalA-3ewmA:
33.5		 4kalA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.37A 4kalB-3ewmA:
33.4		 4kalB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.71A 4kalB-3ewmA:
33.4		 4kalB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.35A 4kanA-3ewmA:
33.4		 4kanA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.73A 4kanA-3ewmA:
33.4		 4kanA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.35A 4kanB-3ewmA:
33.5		 4kanB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.73A 4kanB-3ewmA:
33.5		 4kanB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.36A 4kbeA-3ewmA:
33.5		 4kbeA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.68A 4kbeA-3ewmA:
33.5		 4kbeA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.36A 4kbeB-3ewmA:
33.5		 4kbeB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.73A 4kbeB-3ewmA:
33.5		 4kbeB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.36A 4lbgA-3ewmA:
33.3		 4lbgA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.73A 4lbgA-3ewmA:
33.3		 4lbgA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.36A 4lbgB-3ewmA:
33.4		 4lbgB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.75A 4lbgB-3ewmA:
33.4		 4lbgB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.38A 4lbxA-3ewmA:
33.4		 4lbxA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
THR A 243
ASP A 247
 None
 1.10A 4lbxA-3ewmA:
33.4		 4lbxA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.38A 4lbxB-3ewmA:
33.5		 4lbxB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
THR A 243
ASP A 247
 None
 1.11A 4lbxB-3ewmA:
33.5		 4lbxB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.37A 4lc4A-3ewmA:
33.4		 4lc4A-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  34
ASN A  38
LEU A 167
ASP A 247
 None
 1.10A 4lc4A-3ewmA:
33.4		 4lc4A-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
THR A 243
ASP A 247
 None
 1.13A 4lc4A-3ewmA:
33.4		 4lc4A-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.38A 4lc4B-3ewmA:
33.3		 4lc4B-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
THR A 243
ASP A 247
 None
 1.12A 4lc4B-3ewmA:
33.3		 4lc4B-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.35A 4lcaA-3ewmA:
33.4		 4lcaA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.75A 4lcaA-3ewmA:
33.4		 4lcaA-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.35A 4lcaB-3ewmA:
33.5		 4lcaB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
THR A 243
ASP A 247
 None
 0.73A 4lcaB-3ewmA:
33.5		 4lcaB-3ewmA:
25.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		6 / 12 ASP A  13
LEU A 167
GLY A  34
ASN A  38
GLY A 244
ASP A 247
 None
 1.08A 4n09A-3ewmA:
29.8		 4n09A-3ewmA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		7 / 12 ASP A  13
LEU A 167
GLY A  33
GLY A  34
ASN A  38
GLY A 244
ASP A 247
 None
 1.02A 4n09B-3ewmA:
29.8		 4n09B-3ewmA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		7 / 12 ASP A  13
LEU A 167
GLY A  33
GLY A  34
ASN A  38
GLY A 244
ASP A 247
 None
 1.05A 4n09C-3ewmA:
29.8		 4n09C-3ewmA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		7 / 12 ASP A  13
LEU A 167
GLY A  33
GLY A  34
ASN A  38
GLY A 244
ASP A 247
 None
 1.05A 4n09D-3ewmA:
29.7		 4n09D-3ewmA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.30A 4ubeA-3ewmA:
29.2		 4ubeA-3ewmA:
26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		4 / 5 GLY A  20
SER A 100
GLU A  19
ASP A  21
 None
 0.96A 4xueA-3ewmA:
2.5		 4xueA-3ewmA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 ASP A  13
GLY A  33
GLY A  34
ASN A  38
ASP A 247
 None
 0.45A 5kb5A-3ewmA:
29.8		 5kb5A-3ewmA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLY A  33
GLY A  34
ASN A  38
LEU A 103
ASP A 247
 None
 0.89A 5kb5A-3ewmA:
29.8		 5kb5A-3ewmA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 THR A 215
GLY A 217
ALA A 245
GLY A 246
ALA A 276
 None
 0.56A 5kb6A-3ewmA:
28.3		 5kb6A-3ewmA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 THR A 215
GLY A 217
ALA A 245
GLY A 246
ALA A 276
 None
 0.57A 5kb6B-3ewmA:
28.4		 5kb6B-3ewmA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		5 / 12 GLU A  29
ASP A 241
GLY A 284
ALA A  37
ASN A  38
 None
 1.40A 5kbwB-3ewmA:
undetectable		 5kbwB-3ewmA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 3ewm UNCHARACTERIZED
SUGAR KINASE PH1459
(Pyrococcus
horikoshii) 		4 / 7 GLY A  20
SER A 100
GLU A  19
ASP A  21
 None
 0.89A 5n5dB-3ewmA:
3.1		 5n5dB-3ewmA:
21.78