SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ewo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3ewo NON-STRUCTURAL
PROTEIN 3
(Avian
coronavirus) 		5 / 12 HIS A  47
VAL A  51
PHE A 159
VAL A  92
VAL A 125
 None
 1.12A 3czvA-3ewoA:
undetectable
3czvB-3ewoA:
undetectable		 3czvA-3ewoA:
21.85
3czvB-3ewoA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 3ewo NON-STRUCTURAL
PROTEIN 3
(Avian
coronavirus) 		4 / 7 GLY A  48
GLY A  49
ALA A  52
ILE A 133
 None
 0.64A 4yjiA-3ewoA:
undetectable		 4yjiA-3ewoA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 3ewo NON-STRUCTURAL
PROTEIN 3
(Avian
coronavirus) 		5 / 7 ASN A  93
VAL A 116
SER A 115
ALA A 112
GLY A  97
 None
 1.42A 5fpdB-3ewoA:
undetectable		 5fpdB-3ewoA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3ewo NON-STRUCTURAL
PROTEIN 3
(Avian
coronavirus) 		4 / 7 LEU A 129
PRO A 127
ILE A  55
MET A  45
 None
 0.92A 5fxtA-3ewoA:
undetectable		 5fxtA-3ewoA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 3ewo NON-STRUCTURAL
PROTEIN 3
(Avian
coronavirus) 		4 / 4 ASN A  39
SER A  46
ALA A  41
VAL A  96
 None
 1.36A 5nm5A-3ewoA:
undetectable		 5nm5A-3ewoA:
17.37