SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3exn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.93A 1v55P-3exnA:
undetectable
1v55W-3exnA:
undetectable		 1v55P-3exnA:
23.02
1v55W-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.84A 2dysC-3exnA:
undetectable
2dysJ-3exnA:
undetectable		 2dysC-3exnA:
23.02
2dysJ-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.87A 2dysP-3exnA:
undetectable
2dysW-3exnA:
undetectable		 2dysP-3exnA:
23.02
2dysW-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.91A 2eijP-3exnA:
undetectable
2eijW-3exnA:
undetectable		 2eijP-3exnA:
23.02
2eijW-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.85A 2zxwC-3exnA:
undetectable
2zxwJ-3exnA:
undetectable		 2zxwC-3exnA:
23.02
2zxwJ-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.83A 2zxwP-3exnA:
undetectable
2zxwW-3exnA:
undetectable		 2zxwP-3exnA:
23.02
2zxwW-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.89A 3abkP-3exnA:
undetectable
3abkW-3exnA:
undetectable		 3abkP-3exnA:
23.02
3abkW-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.84A 3ag1C-3exnA:
undetectable
3ag1J-3exnA:
undetectable		 3ag1C-3exnA:
23.02
3ag1J-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 LEU A  92
TYR A  73
LEU A  63
ARG A  94
 ACO  A1001 (-4.3A)
None
None
None
 0.93A 3f33A-3exnA:
undetectable		 3f33A-3exnA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 LEU A  92
TYR A  73
LEU A  63
LEU A  90
 ACO  A1001 (-4.3A)
None
None
ACO  A1001 (-4.7A)
 1.01A 3f33A-3exnA:
undetectable		 3f33A-3exnA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		3 / 3 PHE A  65
TYR A  73
LEU A   7
 None
None
CL  A 159 (-4.4A)
 0.77A 3keeB-3exnA:
undetectable		 3keeB-3exnA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 1.00A 3wg7P-3exnA:
undetectable
3wg7W-3exnA:
undetectable		 3wg7P-3exnA:
23.02
3wg7W-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		5 / 11 ALA A  76
ALA A  86
VAL A 117
LEU A 120
LEU A 107
 None
 0.97A 5eb5A-3exnA:
undetectable		 5eb5A-3exnA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_1
(CDL2.3B)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		5 / 12 PHE A 135
LEU A  74
PHE A 140
ALA A  86
LEU A 114
 ACO  A1001 (-4.3A)
None
None
None
None
 0.97A 5iepA-3exnA:
undetectable		 5iepA-3exnA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.89A 5iy5C-3exnA:
undetectable
5iy5J-3exnA:
undetectable		 5iy5C-3exnA:
23.11
5iy5J-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.86A 5iy5P-3exnA:
undetectable
5iy5W-3exnA:
undetectable		 5iy5P-3exnA:
23.11
5iy5W-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 6 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.80A 5w97C-3exnA:
undetectable
5w97J-3exnA:
undetectable		 5w97C-3exnA:
23.02
5w97J-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.85A 5x1fC-3exnA:
undetectable
5x1fJ-3exnA:
undetectable		 5x1fC-3exnA:
23.02
5x1fJ-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.92A 5xdxC-3exnA:
undetectable
5xdxJ-3exnA:
undetectable		 5xdxC-3exnA:
23.11
5xdxJ-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 5 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.92A 5xdxP-3exnA:
undetectable
5xdxW-3exnA:
undetectable		 5xdxP-3exnA:
23.11
5xdxW-3exnA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3exn PROBABLE
ACETYLTRANSFERASE
(Thermus
thermophilus) 		4 / 7 LEU A  63
PHE A  62
LEU A  22
PHE A  26
 None
 0.91A 5z84C-3exnA:
undetectable
5z84J-3exnA:
undetectable		 5z84C-3exnA:
23.02
5z84J-3exnA:
19.20