SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3exq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_C_ADNC603_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3exq NUDIX FAMILY
HYDROLASE
(Lactobacillus
brevis) 		4 / 5 THR A  64
GLU A  59
THR A  13
LEU A  68
 None
SO4  A 201 ( 4.1A)
None
None
 1.32A 1d4fC-3exqA:
undetectable		 1d4fC-3exqA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3exq NUDIX FAMILY
HYDROLASE
(Lactobacillus
brevis) 		4 / 4 GLN A   7
PRO A   8
VAL A   9
GLU A  10
 None
 0.99A 3huoA-3exqA:
undetectable		 3huoA-3exqA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3exq NUDIX FAMILY
HYDROLASE
(Lactobacillus
brevis) 		3 / 3 THR A 137
HIS A  39
LEU A 127
 None
 0.83A 5axdC-3exqA:
undetectable		 5axdC-3exqA:
14.55