SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eyb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		6 / 12 TRP A 334
PHE A 342
LEU A 355
ALA A 356
VAL A 371
CYH A 461
 None
 1.08A 1fm6U-3eybA:
27.6		 1fm6U-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		7 / 12 TRP A 334
PHE A 342
LEU A 355
VAL A 371
ILE A 374
CYH A 461
HIS A 464
 None
 1.08A 1fm6U-3eybA:
27.6		 1fm6U-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 LEU A 338
PHE A 342
ALA A 356
VAL A 371
CYH A 461
 None
 0.91A 1fm9A-3eybA:
28.1		 1fm9A-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		6 / 12 ASN A 335
PHE A 342
LEU A 355
ALA A 356
VAL A 371
CYH A 461
 None
 0.90A 1xdkA-3eybA:
28.1		 1xdkA-3eybA:
84.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 PHE A 342
LEU A 355
ALA A 356
VAL A 371
CYH A 461
 None
 0.98A 1xdkE-3eybA:
28.1		 1xdkE-3eybA:
84.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 LEU A 338
PHE A 342
ALA A 356
VAL A 371
CYH A 461
 None
 0.78A 1xiuB-3eybA:
28.6		 1xiuB-3eybA:
84.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 LEU A 338
PHE A 342
VAL A 371
CYH A 461
HIS A 464
 None
 0.72A 1xiuB-3eybA:
28.6		 1xiuB-3eybA:
84.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 ASN A 335
LEU A 338
PHE A 342
ALA A 356
CYH A 461
 None
 0.81A 2aclA-3eybA:
28.0
2aclE-3eybA:
27.8		 2aclA-3eybA:
84.14
2aclE-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 ASN A 335
LEU A 338
PHE A 342
ILE A 374
CYH A 461
 None
 0.89A 2aclA-3eybA:
28.0
2aclE-3eybA:
27.8		 2aclA-3eybA:
84.14
2aclE-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 ASN A 335
PHE A 342
LEU A 355
ALA A 356
CYH A 461
 None
 1.01A 2aclA-3eybA:
28.0
2aclE-3eybA:
27.8		 2aclA-3eybA:
84.14
2aclE-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 11 ASN A 335
LEU A 338
PHE A 342
ALA A 356
CYH A 461
 None
 0.94A 2aclE-3eybA:
27.8		 2aclE-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 ILE A 339
PHE A 342
LEU A 355
ALA A 356
CYH A 461
 None
 0.92A 2aclG-3eybA:
27.1		 2aclG-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 LEU A 338
ILE A 339
PHE A 342
ALA A 356
CYH A 461
 None
 0.82A 2aclG-3eybA:
27.1		 2aclG-3eybA:
84.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		4 / 5 LEU A 329
ASP A 325
ALA A 409
ILE A 328
 None
 1.04A 2aofB-3eybA:
undetectable		 2aofB-3eybA:
19.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 ASN A 335
ILE A 339
PHE A 342
LEU A 355
VAL A 371
 None
 1.04A 3dzuA-3eybA:
27.2		 3dzuA-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		6 / 12 ILE A 339
PHE A 342
LEU A 355
VAL A 371
CYH A 461
HIS A 464
 None
 0.99A 3dzuA-3eybA:
27.2		 3dzuA-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 ASN A 335
PHE A 342
VAL A 371
ILE A 374
CYH A 461
 None
 0.76A 3e00A-3eybA:
28.2		 3e00A-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OAP_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		6 / 12 PHE A 342
LEU A 355
ALA A 356
VAL A 371
ILE A 374
CYH A 461
 None
 1.06A 3oapA-3eybA:
29.3		 3oapA-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 LEU A 338
PHE A 342
VAL A 371
ILE A 374
CYH A 461
 None
 0.63A 3uvvB-3eybA:
28.8		 3uvvB-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 LEU A 338
ILE A 339
PHE A 342
ALA A 356
VAL A 378
 None
 0.61A 4k6iA-3eybA:
29.0		 4k6iA-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NQA_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 11 PHE A 342
LEU A 355
VAL A 371
CYH A 461
HIS A 464
 None
 1.15A 4nqaA-3eybA:
26.8		 4nqaA-3eybA:
84.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 11 LEU A 338
PHE A 342
ALA A 356
VAL A 371
CYH A 461
 None
 0.81A 5ji0A-3eybA:
28.4		 5ji0A-3eybA:
83.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JI0_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 11 PHE A 342
LEU A 355
ALA A 356
VAL A 371
CYH A 461
 None
 1.03A 5ji0A-3eybA:
28.4		 5ji0A-3eybA:
83.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 LEU A 338
PHE A 342
ALA A 356
VAL A 371
CYH A 461
 None
 0.85A 5z12B-3eybA:
28.4		 5z12B-3eybA:
75.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Y_D_9CRD501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		3 / 3 ASN A 335
VAL A 371
HIS A 464
 None
 0.60A 6a5yD-3eybA:
29.0		 6a5yD-3eybA:
75.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3eyb NUCLEAR HORMONE
RECEPTOR RXR
(Branchiostoma
floridae) 		5 / 12 ILE A 339
PHE A 342
LEU A 355
ALA A 356
CYH A 461
 None
 0.79A 6a5zD-3eybA:
29.0		 6a5zD-3eybA:
75.00