SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eye'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 3eye PTS SYSTEM
N-ACETYLGALACTOSAMIN
E-SPECIFIC IIB
COMPONENT 1
(Escherichia
coli) 		3 / 3 LEU A  15
ASN A  13
ARG A  87
 None
 0.85A 2qhfA-3eyeA:
undetectable		 2qhfA-3eyeA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 3eye PTS SYSTEM
N-ACETYLGALACTOSAMIN
E-SPECIFIC IIB
COMPONENT 1
(Escherichia
coli) 		4 / 7 GLY A 108
ASP A 147
ASP A 151
ILE A 119
 None
 0.76A 3t3cA-3eyeA:
undetectable		 3t3cA-3eyeA:
25.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)		 3eye PTS SYSTEM
N-ACETYLGALACTOSAMIN
E-SPECIFIC IIB
COMPONENT 1
(Escherichia
coli) 		4 / 8 TRP A  24
GLY A 150
PRO A 149
ASP A 151
 None
 1.11A 5kgpA-3eyeA:
undetectable		 5kgpA-3eyeA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBZ_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 3eye PTS SYSTEM
N-ACETYLGALACTOSAMIN
E-SPECIFIC IIB
COMPONENT 1
(Escherichia
coli) 		5 / 11 PHE A  83
LEU A  33
SER A  26
GLY A  29
ILE A  28
 None
 0.87A 6ebzC-3eyeA:
undetectable		 6ebzC-3eyeA:
17.47