SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eyf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 3eyf AD-2
(Homo
sapiens) 		4 / 7 LEU B  81
THR B  61
TYR B  60
LYS B  65
 None
 1.00A 1rmtB-3eyfB:
undetectable		 1rmtB-3eyfB:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_D_SAMD301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3eyf AD-2
(Homo
sapiens) 		5 / 12 GLY B 110
SER B 109
ASP B 113
ARG B  98
LEU B 112
 None
 1.32A 3iv6D-3eyfB:
undetectable		 3iv6D-3eyfB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 3eyf AD-2
(Homo
sapiens) 		3 / 3 PRO B 197
SER B 199
SER B 200
 None
 0.48A 6bpyA-3eyfB:
undetectable		 6bpyA-3eyfB:
21.96