SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3eyk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus;
Influenza
A
virus) 		5 / 11 GLU A  89
GLU B  67
ALA A 113
PHE A  87
GLY A 116
 None
 1.35A 1cmaA-3eykA:
undetectable
1cmaB-3eykA:
undetectable		 1cmaA-3eykA:
13.19
1cmaB-3eykA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus;
Influenza
A
virus) 		5 / 10 ALA A 113
PHE A  87
GLY A 116
GLU A  89
GLU B  67
 None
 1.26A 1cmcA-3eykA:
undetectable
1cmcB-3eykA:
undetectable		 1cmcA-3eykA:
13.19
1cmcB-3eykA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_B_SAMB105_0
(MET REPRESSOR)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus;
Influenza
A
virus) 		5 / 10 GLU A  89
GLU B  67
ALA A 113
PHE A  87
GLY A 116
 None
 1.28A 1cmcA-3eykA:
undetectable
1cmcB-3eykA:
undetectable		 1cmcA-3eykA:
13.19
1cmcB-3eykA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 196
THR A 155
LEU A 253
GLY A 251
 None
 0.74A 1gtiB-3eykA:
undetectable		 1gtiB-3eykA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_A_SAMA200_0
(METHIONINE REPRESSOR)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus;
Influenza
A
virus) 		5 / 11 GLU A  89
GLU B  67
ALA A 113
PHE A  87
GLY A 116
 None
 1.28A 1mjqA-3eykA:
undetectable
1mjqB-3eykA:
undetectable		 1mjqA-3eykA:
13.80
1mjqB-3eykA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus;
Influenza
A
virus) 		5 / 10 GLU A  89
GLU B  67
ALA A 113
PHE A  87
GLY A 116
 None
 1.31A 1mjqC-3eykA:
undetectable
1mjqD-3eykA:
undetectable		 1mjqC-3eykA:
13.80
1mjqD-3eykA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_G_SAMG199_0
(METHIONINE REPRESSOR)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus;
Influenza
A
virus) 		5 / 10 GLU A  89
GLU B  67
ALA A 113
PHE A  87
GLY A 116
 None
 1.28A 1mjqG-3eykA:
undetectable
1mjqH-3eykA:
undetectable		 1mjqG-3eykA:
13.80
1mjqH-3eykA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus;
Influenza
A
virus) 		5 / 11 GLU A  89
GLU B  67
ALA A 113
PHE A  87
GLY A 116
 None
 1.32A 1mjqI-3eykA:
undetectable
1mjqJ-3eykA:
undetectable		 1mjqI-3eykA:
13.80
1mjqJ-3eykA:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		3 / 3 ASP A  77
PHE A 120
ASN A  68
 None
 0.66A 1sg9B-3eykA:
undetectable		 1sg9B-3eykA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		3 / 3 ALA A 157
VAL A 132
TRP A 127
 None
 0.92A 1tkqB-3eykA:
undetectable		 1tkqB-3eykA:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.96A 1v55C-3eykA:
undetectable
1v55J-3eykA:
undetectable		 1v55C-3eykA:
21.21
1v55J-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.97A 1v55P-3eykA:
undetectable
1v55W-3eykA:
undetectable		 1v55P-3eykA:
21.21
1v55W-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 1.00A 2dysC-3eykA:
undetectable
2dysJ-3eykA:
undetectable		 2dysC-3eykA:
21.21
2dysJ-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.99A 2dysP-3eykA:
undetectable
2dysW-3eykA:
undetectable		 2dysP-3eykA:
21.21
2dysW-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.96A 2eijC-3eykA:
undetectable
2eijJ-3eykA:
undetectable		 2eijC-3eykA:
21.21
2eijJ-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.99A 2eijP-3eykA:
undetectable
2eijW-3eykA:
undetectable		 2eijP-3eykA:
21.21
2eijW-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 6 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.97A 2einP-3eykA:
undetectable
2einW-3eykA:
undetectable		 2einP-3eykA:
21.21
2einW-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 8 ILE A  88
GLY A  61
LEU A  79
LEU A 118
 None
 0.88A 2vctC-3eykA:
undetectable		 2vctC-3eykA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.96A 2zxwC-3eykA:
undetectable
2zxwJ-3eykA:
undetectable		 2zxwC-3eykA:
21.21
2zxwJ-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 6 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.98A 3ag1C-3eykA:
undetectable
3ag1J-3eykA:
undetectable		 3ag1C-3eykA:
21.21
3ag1J-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 1.01A 3ag2C-3eykA:
undetectable		 3ag2C-3eykA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.98A 3ag2P-3eykA:
undetectable
3ag2W-3eykA:
undetectable		 3ag2P-3eykA:
21.21
3ag2W-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 ASP A  85
SER A 269
SER A 117
GLU A 119
 None
 1.25A 3bc9A-3eykA:
undetectable		 3bc9A-3eykA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus;
Influenza
A
virus) 		5 / 11 GLY A  16
THR B  34
ASP B 112
ALA B   5
ILE B  10
 None
 1.29A 3id5B-3eykA:
undetectable		 3id5B-3eykA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus;
Influenza
A
virus) 		5 / 11 GLY A  16
THR B  34
ASP B 112
ALA B   5
ILE B  10
 None
 1.29A 3id5F-3eykA:
undetectable		 3id5F-3eykA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus) 		6 / 12 ILE A  12
ASN B  28
THR B  34
GLY B  33
THR B  32
GLY B  31
 None
 0.94A 3ny4A-3eykA:
undetectable		 3ny4A-3eykA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus) 		4 / 7 GLY B  13
PRO A 328
GLY A  23
THR A  24
 None
 0.72A 3tajA-3eykB:
undetectable		 3tajA-3eykB:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.87A 3x2qC-3eykA:
undetectable
3x2qJ-3eykA:
undetectable		 3x2qC-3eykA:
21.21
3x2qJ-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.87A 3x2qP-3eykA:
undetectable
3x2qW-3eykA:
undetectable		 3x2qP-3eykA:
21.21
3x2qW-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus) 		3 / 3 LYS A  40
THR A 322
ILE B  45
 None
 0.90A 4e0fB-3eykA:
undetectable		 4e0fB-3eykA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 196
TYR A 197
ILE A 254
GLY A 134
 None
 0.97A 4eq4A-3eykA:
undetectable		 4eq4A-3eykA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus) 		4 / 7 ILE B 108
GLY A  23
ALA A 321
GLN B  15
 None
 0.98A 4g0uB-3eykB:
undetectable		 4g0uB-3eykB:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 6 LEU A 196
TYR A 197
ILE A 254
GLY A 134
 None
 0.96A 4l39A-3eykA:
undetectable		 4l39A-3eykA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 196
TYR A 197
ILE A 254
GLY A 134
 None
 0.95A 4l39B-3eykA:
undetectable		 4l39B-3eykA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		3 / 3 ASP A  65
TRP A 236
SER A  73
 None
 0.91A 4lrhA-3eykA:
undetectable		 4lrhA-3eykA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 6 TYR A 176
GLU A 123
TYR A 180
LEU A 179
 None
 1.21A 4twdB-3eykA:
undetectable
4twdC-3eykA:
undetectable		 4twdB-3eykA:
22.47
4twdC-3eykA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 6 TYR A 176
GLU A 123
TYR A 180
LEU A 179
 None
 1.21A 4twdD-3eykA:
undetectable
4twdE-3eykA:
undetectable		 4twdD-3eykA:
22.47
4twdE-3eykA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.89A 5b1aC-3eykA:
undetectable
5b1aJ-3eykA:
undetectable		 5b1aC-3eykA:
21.21
5b1aJ-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.86A 5b1aP-3eykA:
undetectable
5b1aW-3eykA:
undetectable		 5b1aP-3eykA:
21.21
5b1aW-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.90A 5b3sC-3eykA:
undetectable
5b3sJ-3eykA:
undetectable		 5b3sC-3eykA:
21.21
5b3sJ-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.89A 5b3sP-3eykA:
undetectable		 5b3sP-3eykA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus) 		5 / 11 LEU B  99
ALA B  96
LEU A 318
MET A 319
LEU A 320
 EYK  B 173 (-4.6A)
None
None
None
None
 1.46A 5hyrB-3eykB:
undetectable		 5hyrB-3eykB:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.90A 5iy5C-3eykA:
undetectable
5iy5J-3eykA:
undetectable		 5iy5C-3eykA:
21.21
5iy5J-3eykA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus) 		5 / 12 LEU B  52
LEU A  42
GLY A 323
ALA A 321
SER A  38
 None
 1.05A 5jvzA-3eykB:
undetectable		 5jvzA-3eykB:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ONL_A_010A302_0
(YNDL)		 3eyk HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus) 		4 / 5 GLU B  81
GLU B  67
GLU B  74
PHE B  70
 None
 1.31A 5onlA-3eykB:
undetectable		 5onlA-3eykB:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.88A 5z84C-3eykA:
undetectable
5z84J-3eykA:
undetectable		 5z84C-3eykA:
21.21
5z84J-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.89A 5z85C-3eykA:
undetectable
5z85J-3eykA:
undetectable		 5z85C-3eykA:
21.21
5z85J-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.86A 5zcoC-3eykA:
undetectable
5zcoJ-3eykA:
undetectable		 5zcoC-3eykA:
21.21
5zcoJ-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		4 / 7 LEU A 118
GLN A  80
PHE A 120
LEU A 112
 None
 0.94A 5zcqC-3eykA:
undetectable
5zcqJ-3eykA:
undetectable		 5zcqC-3eykA:
21.21
5zcqJ-3eykA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus) 		6 / 12 ILE A  12
ASN B  28
THR B  34
GLY B  33
THR B  32
GLY B  31
 None
 0.94A 6b6aD-3eykA:
undetectable		 6b6aD-3eykA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CE2_B_SVRB202_2
(-)		 3eyk HEMAGGLUTININ HA1
CHAIN
(Influenza
A
virus) 		5 / 12 LEU A 181
GLY A  72
GLY A  69
ARG A 109
LYS A 261
 None
 1.13A 6ce2B-3eykA:
undetectable		 6ce2B-3eykA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 3eyk HEMAGGLUTININ HA1
CHAIN
HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus;
Influenza
A
virus) 		4 / 5 ASN B  12
TYR B  22
GLY B  20
HIS A  17
 None
 1.24A 6gh9A-3eykB:
undetectable		 6gh9A-3eykB:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HRJ_A_010A302_0
(YNDL)		 3eyk HEMAGGLUTININ HA2
CHAIN
(Influenza
A
virus) 		4 / 5 GLU B  81
GLU B  67
GLU B  74
PHE B  70
 None
 1.32A 6hrjA-3eykB:
undetectable		 6hrjA-3eykB:
22.66