SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ezu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 3ezu GGDEF DOMAIN PROTEIN
(Geobacter
sulfurreducens) 		3 / 3 LEU A 134
PRO A 135
ARG A 175
 None
 0.55A 2qd4B-3ezuA:
undetectable		 2qd4B-3ezuA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 3ezu GGDEF DOMAIN PROTEIN
(Geobacter
sulfurreducens) 		4 / 6 THR A 247
GLU A 244
LYS A   0
ILE A  70
 None
 1.38A 2w98B-3ezuA:
undetectable		 2w98B-3ezuA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 3ezu GGDEF DOMAIN PROTEIN
(Geobacter
sulfurreducens) 		4 / 8 PHE A  39
ALA A  28
ALA A  44
THR A  47
 None
None
None
UNL  A 342 ( 4.3A)
 1.11A 3t3sE-3ezuA:
undetectable		 3t3sE-3ezuA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 3ezu GGDEF DOMAIN PROTEIN
(Geobacter
sulfurreducens) 		5 / 10 ASP A 313
ALA A 205
TYR A 204
GLY A 315
SER A 201
 None
 1.35A 4mmdA-3ezuA:
undetectable		 4mmdA-3ezuA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ezu GGDEF DOMAIN PROTEIN
(Geobacter
sulfurreducens) 		4 / 7 ILE A 246
ARG A 284
THR A 298
LEU A 220
 None
 0.94A 5b1aA-3ezuA:
1.8
5b1aJ-3ezuA:
undetectable		 5b1aA-3ezuA:
21.10
5b1aJ-3ezuA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ezu GGDEF DOMAIN PROTEIN
(Geobacter
sulfurreducens) 		4 / 7 ILE A 246
ARG A 284
THR A 298
LEU A 220
 None
 0.93A 5b3sA-3ezuA:
1.5
5b3sJ-3ezuA:
undetectable		 5b3sA-3ezuA:
21.10
5b3sJ-3ezuA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_F_CCSF14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)		 3ezu GGDEF DOMAIN PROTEIN
(Geobacter
sulfurreducens) 		4 / 6 PHE A  27
TRP A  40
SER A 100
GLY A  32
 None
 0.96A 5o4yF-3ezuA:
undetectable		 5o4yF-3ezuA:
3.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ezu GGDEF DOMAIN PROTEIN
(Geobacter
sulfurreducens) 		4 / 5 LEU A 170
ALA A 174
LEU A 177
LEU A 115
 None
 0.84A 5vkqA-3ezuA:
undetectable
5vkqD-3ezuA:
undetectable		 5vkqA-3ezuA:
11.43
5vkqD-3ezuA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3ezu GGDEF DOMAIN PROTEIN
(Geobacter
sulfurreducens) 		4 / 5 LEU A 115
LEU A 170
ALA A 174
LEU A 177
 None
 0.88A 5vkqC-3ezuA:
undetectable
5vkqD-3ezuA:
undetectable		 5vkqC-3ezuA:
11.43
5vkqD-3ezuA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 3ezu GGDEF DOMAIN PROTEIN
(Geobacter
sulfurreducens) 		4 / 8 GLY A 107
LEU A 110
SER A  21
ALA A  44
 None
 0.87A 5xu8A-3ezuA:
undetectable		 5xu8A-3ezuA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ezu GGDEF DOMAIN PROTEIN
(Geobacter
sulfurreducens) 		4 / 7 ILE A 246
ARG A 284
THR A 298
LEU A 220
 None
 0.90A 5zcpA-3ezuA:
undetectable
5zcpJ-3ezuA:
undetectable		 5zcpA-3ezuA:
21.10
5zcpJ-3ezuA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3ezu GGDEF DOMAIN PROTEIN
(Geobacter
sulfurreducens) 		4 / 7 ILE A 246
ARG A 284
THR A 298
LEU A 220
 None
 0.97A 5zcqA-3ezuA:
undetectable
5zcqJ-3ezuA:
undetectable		 5zcqA-3ezuA:
21.10
5zcqJ-3ezuA:
10.53