SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f0c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 3f0c TRANSCRIPTIONAL
REGULATOR
(Cytophaga
hutchinsonii) 		4 / 6 LEU A  58
SER A 110
PHE A 120
ASP A 111
 None
 1.25A 2vn1B-3f0cA:
undetectable		 2vn1B-3f0cA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3f0c TRANSCRIPTIONAL
REGULATOR
(Cytophaga
hutchinsonii) 		4 / 8 HIS A 101
PHE A  99
SER A 106
LEU A 172
 None
 1.02A 5y2tB-3f0cA:
undetectable		 5y2tB-3f0cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 3f0c TRANSCRIPTIONAL
REGULATOR
(Cytophaga
hutchinsonii) 		3 / 3 GLU A  60
ASP A  54
PRO A  53
 None
 0.64A 6berA-3f0cA:
undetectable		 6berA-3f0cA:
8.14