SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 11 LEU A 100
VAL A 280
GLY A 279
VAL A 317
VAL A 128
 None
 1.22A 1akdA-3f11A:
undetectable		 1akdA-3f11A:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 11 LEU A 100
VAL A 280
GLY A 279
VAL A 317
VAL A 128
 None
 1.14A 2a1nA-3f11A:
undetectable		 2a1nA-3f11A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 10 LEU A 100
VAL A 280
GLY A 279
VAL A 317
VAL A 128
 None
 1.14A 2cp4A-3f11A:
undetectable		 2cp4A-3f11A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 TYR A 164
LEU A 193
ALA A 196
HIS A 274
 None
None
SO4  A 403 ( 3.7A)
None
 1.09A 2wekA-3f11A:
undetectable		 2wekA-3f11A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X9G_A_LYAA1270_2
(PTERIDINE REDUCTASE)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 MET A 138
VAL A 300
GLU A 125
 None
 0.87A 2x9gA-3f11A:
undetectable		 2x9gA-3f11A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 10 PHE A 295
ASP A  97
ALA A 286
VAL A  73
PHE A  65
 None
 1.39A 3ay0A-3f11A:
undetectable		 3ay0A-3f11A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 ALA A 286
VAL A  98
PHE A 140
ILE A 296
SER A 121
 None
 1.30A 4c49A-3f11A:
undetectable		 4c49A-3f11A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7B_C_ACTC513_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		3 / 3 TYR A  55
HIS A  54
ARG A  53
 FE  A 400 (-4.2A)
SO4  A 402 (-3.3A)
None
 0.85A 4e7bC-3f11A:
undetectable		 4e7bC-3f11A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 8 SER A 180
SER A 181
ASN A 186
GLY A 358
 None
 0.87A 4fo4A-3f11A:
undetectable		 4fo4A-3f11A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		6 / 12 ALA A 110
ILE A 296
GLY A 279
ALA A  96
ILE A 115
VAL A  98
 None
 1.13A 4nkxB-3f11A:
undetectable		 4nkxB-3f11A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		6 / 12 ALA A 110
PHE A 116
ILE A 296
GLY A 279
ALA A  96
ILE A 115
 None
 1.47A 4nkxB-3f11A:
undetectable		 4nkxB-3f11A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL A 280
SER A  52
GLN A 305
LEU A 308
LEU A  61
 None
 1.27A 4qztA-3f11A:
undetectable		 4qztA-3f11A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 9 LEU A 100
VAL A 280
GLY A 279
VAL A 317
VAL A 128
 None
 1.25A 5cp4A-3f11A:
undetectable		 5cp4A-3f11A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDM_A_ADNA904_1
(ATP-CITRATE SYNTHASE)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 4 THR A 101
ASP A 103
ARG A 106
LEU A 107
 None
 1.30A 5tdmA-3f11A:
undetectable		 5tdmA-3f11A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		5 / 12 VAL A 128
ILE A 123
ILE A 296
THR A 143
VAL A 317
 None
 0.97A 5uvmB-3f11A:
undetectable		 5uvmB-3f11A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA7_A_TPFA602_0
(CYTOCHROME P450 3A4)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 SER A 339
THR A 202
ILE A 353
ALA A 350
 None
 0.84A 6ma7A-3f11A:
undetectable		 6ma7A-3f11A:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 3f11 IRON TRANSPORT
PROTEIN
(Synechocystis
sp.
PCC
6803) 		4 / 7 HIS A  54
ARG A 147
HIS A 274
ASP A 221
 SO4  A 402 (-3.3A)
None
None
None
 1.40A 6mn4F-3f11A:
undetectable		 6mn4F-3f11A:
23.50