SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f1b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 3f1b TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		4 / 8 ARG A 112
HIS A 103
SER A 106
VAL A  22
 None
SO4  A 204 (-4.2A)
None
None
 1.34A 1u1jA-3f1bA:
undetectable		 1u1jA-3f1bA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 3f1b TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 GLY A 161
LEU A 184
LEU A 187
LEU A 131
LEU A 139
 None
 1.30A 1ya4B-3f1bA:
undetectable		 1ya4B-3f1bA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XNR_A_ACTA1001_0
(NUCLEAR
POLYADENYLATED
RNA-BINDING PROTEIN
3)		 3f1b TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		3 / 3 SER A 126
ARG A 128
GLN A 125
 None
 0.90A 2xnrA-3f1bA:
undetectable		 2xnrA-3f1bA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 3f1b TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		4 / 8 LEU A 187
ILE A 155
PHE A 152
ARG A 190
 None
 0.90A 3b9lA-3f1bA:
3.9		 3b9lA-3f1bA:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DMG_A_SAMA401_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493)		 3f1b TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 12 ARG A 112
ASP A  19
GLU A  43
ALA A  40
ASP A  27
 None
 1.44A 4dmgA-3f1bA:
undetectable		 4dmgA-3f1bA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DMG_B_SAMB401_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA1493)		 3f1b TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		5 / 11 ARG A 112
ASP A  19
GLU A  43
ALA A  40
ASP A  27
 None
 1.41A 4dmgB-3f1bA:
undetectable		 4dmgB-3f1bA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 3f1b TETR-LIKE
TRANSCRIPTIONAL
REGULATOR
(Rhodococcus
jostii) 		3 / 3 SER A  55
TYR A  53
TYR A  50
 None
 0.91A 5lakA-3f1bA:
undetectable
5lakI-3f1bA:
undetectable		 5lakA-3f1bA:
18.07
5lakI-3f1bA:
3.33