SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f1c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 7 LEU A 129
ALA A 128
VAL A 134
VAL A 107
 None
 0.90A 1epbA-3f1cA:
undetectable		 1epbA-3f1cA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1428_0
(FPRA)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 7 PHE A  40
PRO A 168
ALA A   4
PHE A  46
 None
 1.29A 1lquA-3f1cA:
2.7		 1lquA-3f1cA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SKX_A_RFPA1_2
(ORPHAN NUCLEAR
RECEPTOR PXR)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 5 PHE A 171
LEU A 100
MET A  88
LEU A 183
 None
 1.40A 1skxA-3f1cA:
undetectable		 1skxA-3f1cA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 8 GLU A 122
ASN A 124
ASN A  43
ILE A   2
 None
 1.17A 3kp6A-3f1cA:
undetectable
3kp6B-3f1cA:
undetectable		 3kp6A-3f1cA:
22.13
3kp6B-3f1cA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3006_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 6 ASN A  43
ILE A   2
GLU A 122
ASN A 124
 None
 1.02A 3kp6A-3f1cA:
undetectable
3kp6B-3f1cA:
undetectable		 3kp6A-3f1cA:
22.13
3kp6B-3f1cA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 5 ASP A 135
VAL A 137
GLY A 165
ASP A 193
 None
 1.21A 3w9tA-3f1cA:
undetectable		 3w9tA-3f1cA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 5 ASP A 135
VAL A 137
GLY A 165
ASP A 193
 None
 1.20A 3w9tB-3f1cA:
undetectable		 3w9tB-3f1cA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 5 ASP A 135
VAL A 137
GLY A 165
ASP A 193
 None
 1.21A 3w9tC-3f1cA:
undetectable		 3w9tC-3f1cA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 5 ASP A 135
VAL A 137
GLY A 165
ASP A 193
 None
 1.21A 3w9tD-3f1cA:
undetectable		 3w9tD-3f1cA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 5 ASP A 135
VAL A 137
GLY A 165
ASP A 193
 None
 1.21A 3w9tE-3f1cA:
undetectable		 3w9tE-3f1cA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 5 ASP A 135
VAL A 137
GLY A 165
ASP A 193
 None
 1.20A 3w9tF-3f1cA:
undetectable		 3w9tF-3f1cA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 5 ASP A 135
VAL A 137
GLY A 165
ASP A 193
 None
 1.21A 3w9tG-3f1cA:
undetectable		 3w9tG-3f1cA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MF6_A_BEZA303_0
(GLUTATHIONE
S-TRANSFERASE DOMAIN)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 5 THR A 167
PRO A 168
PHE A 171
ASN A 124
 None
 1.25A 4mf6A-3f1cA:
undetectable		 4mf6A-3f1cA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SVL_A_ACTA411_0
(P2X PURINOCEPTOR 3)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		4 / 5 GLN A 169
VAL A 208
ASP A 135
ASN A 124
 None
 1.46A 5svlA-3f1cA:
0.0		 5svlA-3f1cA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 3f1c PUTATIVE
2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
2
(Listeria
monocytogenes) 		5 / 12 ILE A 215
GLN A 166
THR A 136
VAL A 208
VAL A 134
 None
 1.39A 6bzoC-3f1cA:
undetectable		 6bzoC-3f1cA:
13.46