SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f1s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 3f1s VITAMIN K-DEPENDENT
PROTEIN Z
(Homo
sapiens) 		4 / 8 ILE B 168
ASN B 220
VAL B 330
GLY B 329
 None
 0.95A 3em0B-3f1sB:
undetectable		 3em0B-3f1sB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_A_BRLA501_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3f1s VITAMIN K-DEPENDENT
PROTEIN Z
(Homo
sapiens) 		4 / 5 GLY B 164
LEU B 327
LEU B 222
LEU B 227
 None
 0.87A 4o8fA-3f1sB:
undetectable		 4o8fA-3f1sB:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3f1s VITAMIN K-DEPENDENT
PROTEIN Z
(Homo
sapiens) 		3 / 3 TRP B 354
MET B 211
ASN B 220
 None
 1.37A 5uc1B-3f1sB:
undetectable		 5uc1B-3f1sB:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 3f1s VITAMIN K-DEPENDENT
PROTEIN Z
(Homo
sapiens) 		3 / 3 TRP B 354
MET B 211
ASN B 220
 None
 1.39A 5uc1A-3f1sB:
undetectable		 5uc1A-3f1sB:
17.14