SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f1v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_A_IBPA701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		5 / 9 VAL A 321
LEU A 325
ILE A 292
ALA A 270
SER A 274
 None
 0.94A 1eqgA-3f1vA:
undetectable		 1eqgA-3f1vA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQG_B_IBPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		5 / 11 VAL A 321
LEU A 325
ILE A 292
ALA A 270
SER A 274
 None
 0.96A 1eqgB-3f1vA:
undetectable		 1eqgB-3f1vA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		5 / 12 LEU A 331
LEU A 325
VAL A 324
LEU A 256
LEU A 290
 None
 1.00A 1s19A-3f1vA:
undetectable		 1s19A-3f1vA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		4 / 7 LYS A 291
LEU A 290
GLN A 289
PHE A 319
 None
 0.98A 1v55P-3f1vA:
undetectable
1v55W-3f1vA:
undetectable		 1v55P-3f1vA:
21.20
1v55W-3f1vA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		4 / 7 LEU A 306
GLN A 289
LEU A 263
PHE A 267
 None
 1.07A 2eijC-3f1vA:
undetectable
2eijJ-3f1vA:
undetectable		 2eijC-3f1vA:
21.20
2eijJ-3f1vA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		4 / 7 LYS A 291
LEU A 290
GLN A 289
PHE A 319
 None
 0.96A 2eijP-3f1vA:
undetectable
2eijW-3f1vA:
undetectable		 2eijP-3f1vA:
21.20
2eijW-3f1vA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		4 / 8 LEU A 331
ARG A 337
SER A 145
VAL A 347
 None
 0.99A 2qd2A-3f1vA:
undetectable		 2qd2A-3f1vA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		4 / 7 LEU A 306
GLN A 289
LEU A 263
PHE A 267
 None
 0.93A 2zxwC-3f1vA:
undetectable
2zxwJ-3f1vA:
undetectable		 2zxwC-3f1vA:
21.20
2zxwJ-3f1vA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		4 / 6 LEU A 306
GLN A 289
LEU A 263
PHE A 267
 None
 0.88A 3ag1C-3f1vA:
undetectable
3ag1J-3f1vA:
undetectable		 3ag1C-3f1vA:
21.20
3ag1J-3f1vA:
9.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		5 / 12 LEU A 331
LEU A 328
TYR A 359
ILE A 349
PHE A 144
 None
 1.08A 3gwwA-3f1vA:
undetectable		 3gwwA-3f1vA:
19.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MJQ_A_27RA401_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		4 / 5 TYR A 154
THR A 172
PRO A 242
VAL A 247
 None
 1.23A 4mjqA-3f1vA:
49.3		 4mjqA-3f1vA:
98.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MJR_A_0LAA404_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		8 / 9 TYR A 154
THR A 172
GLY A 174
LEU A 177
PRO A 242
VAL A 247
VAL A 360
MET A 362
 None
 0.92A 4mjrA-3f1vA:
50.2		 4mjrA-3f1vA:
98.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_B_QI9B602_0
(CYTOCHROME P450 2D6)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		5 / 9 PHE A  75
LEU A 108
LEU A  82
VAL A   5
VAL A  90
 None
 1.34A 4wnvB-3f1vA:
undetectable		 4wnvB-3f1vA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUK_A_SNPA1236_1
(MROUPO)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		4 / 7 ILE A 317
THR A 293
ILE A 292
PHE A 319
 None
 0.81A 5fukA-3f1vA:
undetectable
5fukB-3f1vA:
undetectable		 5fukA-3f1vA:
20.38
5fukB-3f1vA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 3f1v DNA POLYMERASE III
SUBUNIT BETA
(Escherichia
coli) 		4 / 8 THR A 172
LEU A 177
PRO A 242
MET A 362
 None
 0.62A 5g48A-3f1vA:
37.6		 5g48A-3f1vA:
26.13