SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f1x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 12 LEU A 254
VAL A 278
ILE A 282
VAL A 270
LEU A 267
 None
 1.02A 1s19A-3f1xA:
2.2		 1s19A-3f1xA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 VAL A 174
ILE A  87
LEU A 123
LEU A  83
ALA A  49
 None
 1.28A 2xf3A-3f1xA:
0.5		 2xf3A-3f1xA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 LEU A 231
ALA A 264
VAL A 284
ILE A 259
ILE A 266
 None
 1.00A 3ekpC-3f1xA:
undetectable		 3ekpC-3f1xA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		6 / 10 LEU A 231
ALA A 264
VAL A 284
ILE A 294
ILE A 259
ILE A 266
 None
 1.23A 3ekpD-3f1xA:
undetectable		 3ekpD-3f1xA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		4 / 4 ILE A 160
PHE A 203
ILE A 205
THR A 132
 None
 0.95A 3ia4A-3f1xA:
undetectable		 3ia4A-3f1xA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		6 / 12 LEU A 231
ALA A 264
VAL A 284
ILE A 294
ILE A 259
ILE A 266
 None
 1.27A 3jw2B-3f1xA:
undetectable		 3jw2B-3f1xA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 11 PHE A 203
ILE A 213
ALA A 156
THR A 189
ALA A 185
 None
 0.99A 3mdtB-3f1xA:
undetectable		 3mdtB-3f1xA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		6 / 12 LEU A 231
ALA A 264
VAL A 284
ILE A 294
ILE A 259
ILE A 266
 None
 1.21A 3tl9B-3f1xA:
undetectable		 3tl9B-3f1xA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA802_1
(CATALASE-PEROXIDASE)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		4 / 8 LEU A 126
ILE A 129
GLY A 200
ILE A 199
 None
 0.91A 3wxoA-3f1xA:
undetectable		 3wxoA-3f1xA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 12 ILE A 160
ASP A 133
GLY A 200
ASN A 221
ILE A 199
 None
 1.40A 4djfA-3f1xA:
undetectable		 4djfA-3f1xA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 LEU A 231
ALA A 264
VAL A 284
ILE A 259
ILE A 266
 None
 1.08A 4njuB-3f1xA:
undetectable		 4njuB-3f1xA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 10 LEU A 231
ALA A 264
VAL A 284
ILE A 259
ILE A 266
 None
 1.09A 4njuD-3f1xA:
undetectable		 4njuD-3f1xA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_A_C2FA3000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 12 ILE A 272
ILE A 160
ASP A 133
GLY A 200
ILE A 199
 None
 1.16A 4o1eA-3f1xA:
undetectable		 4o1eA-3f1xA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		5 / 12 LEU A 130
ASN A 162
THR A 189
ALA A 156
ILE A 205
 None
 1.08A 4x1yB-3f1xA:
undetectable		 4x1yB-3f1xA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3f1x SERINE
ACETYLTRANSFERASE
(Bacteroides
vulgatus) 		6 / 12 LEU A 231
ALA A 264
VAL A 284
ILE A 294
ILE A 259
ILE A 266
 None
 1.27A 6dilB-3f1xA:
undetectable		 6dilB-3f1xA:
19.44