SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f2i'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A  40
TRP A 156
ILE A   6
GLY A 136
ALA A 135
 None
 1.05A 2aylB-3f2iA:
undetectable		 2aylB-3f2iA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 PHE A  47
ILE A  50
THR A  52
LEU A  74
LEU A  40
 None
 1.15A 2jn3A-3f2iA:
undetectable		 2jn3A-3f2iA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A  65
THR A  33
THR A  52
LEU A  25
HIS A   8
 None
None
None
None
PO4  A 201 (-3.9A)
 1.10A 3g1uB-3f2iA:
undetectable		 3g1uB-3f2iA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A  65
THR A  33
THR A  52
LEU A  25
HIS A   8
 None
None
None
None
PO4  A 201 (-3.9A)
 1.13A 3g1uD-3f2iA:
undetectable		 3g1uD-3f2iA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Y_A_DIFA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 11 LEU A  40
TRP A 156
ILE A   6
GLY A 136
ALA A 135
 None
 1.12A 3n8yA-3f2iA:
undetectable		 3n8yA-3f2iA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A  40
TRP A 156
ILE A   6
GLY A 136
ALA A 135
 None
 1.06A 3n8zB-3f2iA:
undetectable		 3n8zB-3f2iA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_A_1N1A1000_2
(P38A)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		3 / 3 GLU A  75
LEU A  49
LEU A   5
 None
 0.64A 3ohtA-3f2iA:
undetectable		 3ohtA-3f2iA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OHT_B_1N1B1000_2
(P38A)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		3 / 3 GLU A  75
LEU A  49
LEU A   5
 None
 0.64A 3ohtB-3f2iA:
undetectable		 3ohtB-3f2iA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		3 / 3 ASP A  91
LEU A  90
PHE A  87
 None
 0.72A 4pthA-3f2iA:
undetectable		 4pthA-3f2iA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DB5_A_CYSA503_0
(CYSTEINE DESULFURASE)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 8 ALA A  11
HIS A 110
ARG A  23
THR A  61
 None
PO4  A 201 (-3.9A)
None
None
 1.30A 5db5A-3f2iA:
undetectable
5db5B-3f2iA:
undetectable		 5db5A-3f2iA:
20.30
5db5B-3f2iA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 6 ILE A  10
ILE A 138
LEU A 114
HIS A 110
 None
None
None
PO4  A 201 (-3.9A)
 0.90A 5vkqB-3f2iA:
undetectable
5vkqC-3f2iA:
undetectable		 5vkqB-3f2iA:
7.08
5vkqC-3f2iA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		4 / 6 ILE A  10
ILE A 138
LEU A 114
HIS A 110
 None
None
None
PO4  A 201 (-3.9A)
 0.89A 5vkqC-3f2iA:
undetectable
5vkqD-3f2iA:
undetectable		 5vkqC-3f2iA:
7.08
5vkqD-3f2iA:
7.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 ARG A   7
GLY A 109
LEU A 142
SER A 115
ILE A 138
 PO4  A 201 (-3.9A)
None
None
None
None
 1.10A 5vooA-3f2iA:
undetectable		 5vooA-3f2iA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)		 3f2i ALR0221 PROTEIN
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A 157
ILE A 107
GLY A 109
LEU A   3
ILE A 138
 None
 1.03A 6dh6B-3f2iA:
undetectable		 6dh6B-3f2iA:
22.64