SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f2v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A1H_B_GBNB501_1 (BRANCHED CHAIN AMINOTRANSFERASE)	3f2v	GENERAL STRESS PROTEIN 14 (Treponema denticola)	4 / 8	VAL A 49 THR A 86 GLY A 95 ALA A 97	None	0.81A	2a1hA-3f2vA: undetectable 2a1hB-3f2vA: undetectable	2a1hA-3f2vA: 18.18 2a1hB-3f2vA: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JAY_A_SAMA1102_1 (STRUCTURAL PROTEIN VP3)	3f2v	GENERAL STRESS PROTEIN 14 (Treponema denticola)	3 / 3	ARG A 145 ASP A 60 ASP A 143	None	0.74A	3jayA-3f2vA: undetectable	3jayA-3f2vA: 11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_B_PCFB1806_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3f2v	GENERAL STRESS PROTEIN 14 (Treponema denticola)	4 / 6	ILE A 68 ILE A 6 LEU A 8 HIS A 10	FMN A 201 (-4.5A) None None FMN A 201 (-3.7A)	0.79A	5vkqB-3f2vA: undetectable 5vkqC-3f2vA: undetectable	5vkqB-3f2vA: 6.93 5vkqC-3f2vA: 6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VKQ_C_PCFC1807_0 (NO MECHANORECEPTOR POTENTIAL C ISOFORM L)	3f2v	GENERAL STRESS PROTEIN 14 (Treponema denticola)	4 / 6	ILE A 68 ILE A 6 LEU A 8 HIS A 10	FMN A 201 (-4.5A) None None FMN A 201 (-3.7A)	0.76A	5vkqC-3f2vA: undetectable 5vkqD-3f2vA: undetectable	5vkqC-3f2vA: 6.93 5vkqD-3f2vA: 6.93

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2A1H_B_GBNB501_1","BRANCHED CHAIN AMINOTRANSFERASE;BRANCHED CHAIN AMINOTRANSFERASE","3f2v","GENERAL STRESS PROTEIN 14","Treponema denticola",4,"VAL A  49;THR A  86;GLY A  95;ALA A  97","None","0.81A","2a1hA-3f2vA:undetectable;2a1hB-3f2vA:undetectable","2a1hA-3f2vA:18.18;2a1hB-3f2vA:18.18"],["3JAY_A_SAMA1102_1","STRUCTURAL PROTEIN VP3","3f2v","GENERAL STRESS PROTEIN 14","Treponema denticola",3,"ARG A 145;ASP A  60;ASP A 143","None","0.74A","3jayA-3f2vA:undetectable","3jayA-3f2vA:11.24"],["5VKQ_B_PCFB1806_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3f2v","GENERAL STRESS PROTEIN 14","Treponema denticola",4,"ILE A  68;ILE A   6;LEU A   8;HIS A  10","FMN A 201 (-4.5A);None;None;FMN A 201 (-3.7A)","0.79A","5vkqB-3f2vA:undetectable;5vkqC-3f2vA:undetectable","5vkqB-3f2vA:6.93;5vkqC-3f2vA:6.93"],["5VKQ_C_PCFC1807_0","NO MECHANORECEPTOR POTENTIAL C ISOFORM L","3f2v","GENERAL STRESS PROTEIN 14","Treponema denticola",4,"ILE A  68;ILE A   6;LEU A   8;HIS A  10","FMN A 201 (-4.5A);None;None;FMN A 201 (-3.7A)","0.76A","5vkqC-3f2vA:undetectable;5vkqD-3f2vA:undetectable","5vkqC-3f2vA:6.93;5vkqD-3f2vA:6.93"]]