SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3f2z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QU2_A_MRCA1993_2 (ISOLEUCYL-TRNA SYNTHETASE)	3f2z	UNCHARACTERIZED PROTEIN BF3579 (Bacteroides fragilis)	3 / 3	GLU A 312 TRP A 335 LYS A 293	None	1.29A	1qu2A-3f2zA: undetectable	1qu2A-3f2zA: 10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_A_DIFA1373_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	3f2z	UNCHARACTERIZED PROTEIN BF3579 (Bacteroides fragilis)	4 / 8	ASN A 369 SER A 368 VAL A 426 PHE A 330	None	0.66A	2wekA-3f2zA: undetectable	2wekA-3f2zA: 18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_B_DIFB1373_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	3f2z	UNCHARACTERIZED PROTEIN BF3579 (Bacteroides fragilis)	4 / 8	ASN A 369 SER A 368 VAL A 426 PHE A 330	None	0.72A	2wekB-3f2zA: undetectable	2wekB-3f2zA: 18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OEX_A_CUA602_0 (THIOCYANATE DEHYDROGENASE)	3f2z	UNCHARACTERIZED PROTEIN BF3579 (Bacteroides fragilis)	3 / 3	LYS A 320 HIS A 318 HIS A 321	None	1.17A	5oexA-3f2zA: undetectable	5oexA-3f2zA: 17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OEX_B_CUB602_0 (THIOCYANATE DEHYDROGENASE)	3f2z	UNCHARACTERIZED PROTEIN BF3579 (Bacteroides fragilis)	3 / 3	LYS A 320 HIS A 318 HIS A 321	None	1.22A	5oexB-3f2zA: undetectable	5oexB-3f2zA: 17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OEX_C_CUC603_0 (THIOCYANATE DEHYDROGENASE)	3f2z	UNCHARACTERIZED PROTEIN BF3579 (Bacteroides fragilis)	3 / 3	LYS A 320 HIS A 318 HIS A 321	None	1.20A	5oexC-3f2zA: undetectable	5oexC-3f2zA: 17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OEX_D_CUD603_0 (THIOCYANATE DEHYDROGENASE)	3f2z	UNCHARACTERIZED PROTEIN BF3579 (Bacteroides fragilis)	3 / 3	LYS A 320 HIS A 318 HIS A 321	None	1.14A	5oexD-3f2zA: undetectable	5oexD-3f2zA: 17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6JOG_A_ASCA201_0 (PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE)	3f2z	UNCHARACTERIZED PROTEIN BF3579 (Bacteroides fragilis)	4 / 6	GLY A 424 THR A 425 ARG A 364 SER A 333	None	1.05A	6jogA-3f2zA: undetectable	6jogA-3f2zA: 21.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1QU2_A_MRCA1993_2","ISOLEUCYL-TRNA SYNTHETASE","3f2z","UNCHARACTERIZED PROTEIN BF3579","Bacteroides fragilis",3,"GLU A 312;TRP A 335;LYS A 293","None","1.29A","1qu2A-3f2zA:undetectable","1qu2A-3f2zA:10.83"],["2WEK_A_DIFA1373_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","3f2z","UNCHARACTERIZED PROTEIN BF3579","Bacteroides fragilis",4,"ASN A 369;SER A 368;VAL A 426;PHE A 330","None","0.66A","2wekA-3f2zA:undetectable","2wekA-3f2zA:18.39"],["2WEK_B_DIFB1373_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","3f2z","UNCHARACTERIZED PROTEIN BF3579","Bacteroides fragilis",4,"ASN A 369;SER A 368;VAL A 426;PHE A 330","None","0.72A","2wekB-3f2zA:undetectable","2wekB-3f2zA:18.39"],["5OEX_A_CUA602_0","THIOCYANATE DEHYDROGENASE","3f2z","UNCHARACTERIZED PROTEIN BF3579","Bacteroides fragilis",3,"LYS A 320;HIS A 318;HIS A 321","None","1.17A","5oexA-3f2zA:undetectable","5oexA-3f2zA:17.45"],["5OEX_B_CUB602_0","THIOCYANATE DEHYDROGENASE","3f2z","UNCHARACTERIZED PROTEIN BF3579","Bacteroides fragilis",3,"LYS A 320;HIS A 318;HIS A 321","None","1.22A","5oexB-3f2zA:undetectable","5oexB-3f2zA:17.45"],["5OEX_C_CUC603_0","THIOCYANATE DEHYDROGENASE","3f2z","UNCHARACTERIZED PROTEIN BF3579","Bacteroides fragilis",3,"LYS A 320;HIS A 318;HIS A 321","None","1.20A","5oexC-3f2zA:undetectable","5oexC-3f2zA:17.45"],["5OEX_D_CUD603_0","THIOCYANATE DEHYDROGENASE","3f2z","UNCHARACTERIZED PROTEIN BF3579","Bacteroides fragilis",3,"LYS A 320;HIS A 318;HIS A 321","None","1.14A","5oexD-3f2zA:undetectable","5oexD-3f2zA:17.45"],["6JOG_A_ASCA201_0","PHOSPHOPANTETHEINE ADENYLYLTRANSFERASE","3f2z","UNCHARACTERIZED PROTEIN BF3579","Bacteroides fragilis",4,"GLY A 424;THR A 425;ARG A 364;SER A 333","None","1.05A","6jogA-3f2zA:undetectable","6jogA-3f2zA:21.88"]]